Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sally Clode"'
Autor:
Monica Longo, Jon Rhodes, Thomas Rückle, Joseph Kinney, Robert L. Clark, Don K. Walker, Anna Christine Huber, Tammye L. Edwards, Timothy N. C. Wells, Nicole Andenmatten, Sally Clode
Publikováno v:
Birth Defects Research. 110:553-578
Background Combination medicines including an artemisinin are the mainstay of antimalarial therapy. Artemisinins are potent embryotoxicants in animal species due to their trioxane moiety. Methods As part of its development, the new synthetic trioxola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a30e1a21f41734b8e019448431cd69
https://doi.org/10.1002/bdr2.1170
https://doi.org/10.1002/bdr2.1170
Autor:
David R. Bell, Ming Qi Fan, Martin Rose, Tao Jiang, Alan D. MacNicoll, Sally Clode, Brian G Miller, Lang Tran, Alwyn Fernandes, Shaun White, Paul M. D. Foster, George Loizou
Publikováno v:
Food and Chemical Toxicology. 48:1439-1447
There have been several studies on the maternal administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and effects in the reproductive tract of male offspring, subsequent to risk assessments undertaken in 2001. This review compares the methodol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c9df34d7c4ed5b4cc42af1621dd9a6
https://doi.org/10.1016/j.fct.2010.04.005
https://doi.org/10.1016/j.fct.2010.04.005
Publikováno v:
Birth Defects Research Part B: Developmental and Reproductive Toxicology. 71:380-394
The artemisinins are playing an increasingly important role in treating multidrug-resistant malaria. The artemisinin, artesunate, is currently in use in Southeast Asia and is advocated for use in Africa. In these areas, more than one million people d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588e0ddcb8f259e44ec1f03dd3895da8
https://doi.org/10.1002/bdrb.20027
https://doi.org/10.1002/bdrb.20027
Autor:
David R. Bell, Tao Jiang, Shaun White, Paul M. D. Foster, Ming Qi Fan, Martin Rose, Sally Clode, Brian G Miller, George Loizou, Lang Tran, Alan D. MacNicoll, Alwyn Fernandes
The aryl hydrocarbon receptor (AhR) is required for the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), and so the AhR of CRL:WI and CRL:WI(Han) rats was characterized. Western blot showed AhR proteins of approximately 110 and approximately 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f622f3d4ac1ca63b9461ac5762173b
http://eprints.nottingham.ac.uk/1066/
http://eprints.nottingham.ac.uk/1066/
Autor:
Shaun White, David R. Bell, Brian G Miller, Alwyn Fernandes, Paul M. D. Foster, Lang Tran, Osama A. Shaikh-Omar, Alan D. MacNicoll, George Loizou, Ming Qi Fan, Alex Bell, Martin Rose, Jeffrey R. Fry, Tao Jiang, Sally Clode
Publikováno v:
University of Manchester-PURE
Recombinant expression of the Aryl Hydrocarbon Receptor (AhR) yields small amounts of ligand- binding competent AhR. Therefore, Spodoptera frugiperda (Sf9) cells and baculovirus have been evaluated for high level and functional expression of AhR. Rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f18f61031455d4cad10da258a690ac1
http://eprints.nottingham.ac.uk/1067/
http://eprints.nottingham.ac.uk/1067/
Autor:
Alwyn Fernandes, Tao Jiang, Lang Tran, George Loizou, David R. Bell, Sally Clode, MingQi Fan, Martin Rose, Brian G Miller, Shaun White, Paul M. D. Foster, Alan D. MacNicoll
Publikováno v:
University of Manchester-PURE
We compared the effects of a single acute dose, or chronic fetal exposure, to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the male reproductive system of the Wistar(Han) rat. Tissue samples were taken from dams on gestation day (GD)16 and GD21, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604275261dc145e73b6534ba5d7eb320
http://eprints.nottingham.ac.uk/726/
http://eprints.nottingham.ac.uk/726/
Autor:
Brian G Miller, David R. Bell, Lang Tran, Shaun White, Sally Clode, Alwyn Fernandes, Tao Jiang, Paul M. D. Foster, Martin Rose, George Loizou, MingQi Fan, Alan D. MacNicoll
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 99(1)
We have investigated whether fetal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes defects in the male reproductive system of the rat using chronically exposed rats to ensure continuous exposure of the fetus. Five- to six-week-old rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01feb080239a77eb8e1d5e34451929aa
https://pubmed.ncbi.nlm.nih.gov/17545211
https://pubmed.ncbi.nlm.nih.gov/17545211
Autor:
David R. Bell, Alwyn R. Fernandes, Brian G Miller, Lang Tran, Martin Rose, Sally Clode, Shaun White, Paul M. D. Foster, George Loizou, Alan D. MacNicoll
Publikováno v:
University of Manchester-PURE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f36429ee2791775b7e83047702b002
https://doi.org/10.1016/j.toxlet.2006.07.019
https://doi.org/10.1016/j.toxlet.2006.07.019
Autor:
Martin Rose, Paul M. D. Foster, Brian G Miller, Alan D. MacNicoll, Shaun White, David R. Bell, Sally Clode, George Loizou, Tao Jiang, Alwyn Fernandes, Lang Tran, MingQi Fan
Publikováno v:
University of Manchester-PURE
It has been reported that fetal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes defects in the male reproductive system of the rat. We set out to replicate and extend these effects using a robust experimental design. Groups of 75 (contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::822282732efa0296f44664c85e49fdb9
https://research.manchester.ac.uk/en/publications/8278200e-c405-41fd-8f37-42f9bbd90cf4
https://research.manchester.ac.uk/en/publications/8278200e-c405-41fd-8f37-42f9bbd90cf4
Autor:
Tao Jiang, David R. Bell, Sally Clode, Ming Qi Fan, Alwyn Fernandes, Paul M. D. Foster, George Loizou, Alan MacNicoll, Brian G. Miller, Martin Rose, Lang Tran, Shaun White
Publikováno v:
Toxicological Sciences; Feb2009, Vol. 107 Issue 2, p512-512, 1p