Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Sally A. Lorimore"'
In addition to the directly mutagenic effects of energy deposition in DNA, ionizing radiation is associated with a variety of untargeted and delayed effects that result in ongoing bone marrow damage. Delayed effects are genotype dependent with CBA/Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cae8a21e81edb8201139b085986abfa
https://doi.org/10.1158/0008-5472.c.6497747.v1
https://doi.org/10.1158/0008-5472.c.6497747.v1
Supplementary Table 1 from Indirect Macrophage Responses to Ionizing Radiation: Implications for Genotype-Dependent Bystander Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d475ca46db25a9312f8520e8bf2e73a
https://doi.org/10.1158/0008-5472.22375238.v1
https://doi.org/10.1158/0008-5472.22375238.v1
Supplementary Table 2 from Indirect Macrophage Responses to Ionizing Radiation: Implications for Genotype-Dependent Bystander Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3399a718580a6dedcb0fab8ab0d5cf1c
https://doi.org/10.1158/0008-5472.22375235
https://doi.org/10.1158/0008-5472.22375235
Supplementary Table 3 from Indirect Macrophage Responses to Ionizing Radiation: Implications for Genotype-Dependent Bystander Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bada2e4d84e737d1b97567b78fac9cd
https://doi.org/10.1158/0008-5472.22375232.v1
https://doi.org/10.1158/0008-5472.22375232.v1
Publikováno v:
The Journal of Pathology. 232:289-299
Since the early years of the twentieth century, the biological consequences of exposure to ionizing radiation have been attributed solely to mutational DNA damage or cell death induced in irradiated cells at the time of exposure. However, numerous ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dfdcd0af5c3d68a1d971e4cd36070ed
https://doi.org/10.1002/path.4299
https://doi.org/10.1002/path.4299
Publikováno v:
International Journal of Radiation Biology. 89:139-146
A study of irradiated (0.25-2 Gy) murine bone marrow has investigated the relationships between apoptotic responses of cells exposed in vivo and in vitro and between in vivo apoptosis and tissue cytotoxicity.The time course of reduction in bone marro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1fa9e29f987bafa59ffe6def0a95dcd
https://doi.org/10.3109/09553002.2013.741280
https://doi.org/10.3109/09553002.2013.741280
Autor:
Susan E. Bray, H. Derek Black, David W. Meek, Sally A. Lorimore, David P. Lane, Frances V. Fuller-Pace, Samantha M. Nicol, Eric G. Wright, Philip J. Coates
Publikováno v:
Oncogene
The RNA helicase p68 (DDX5) is an established co-activator of the p53 tumour suppressor that itself has a pivotal role in orchestrating the cellular response to DNA damage. Although several factors influence the biological outcome of p53 activation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9395dfdf875d95832fd2651af4efc2d
http://europepmc.org/articles/PMC3556166
http://europepmc.org/articles/PMC3556166
Publikováno v:
Radiation Research. 177:584-593
Exposure to ionizing radiation or a variety of chemical agents is known to increase the risk of developing malignancy and many tumors have been linked to inflammatory processes. In most studies, the potentially harmful effects of ionizing radiation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3b85614e3e56c1a8b1e5facf056785
https://doi.org/10.1667/rr2690.1
https://doi.org/10.1667/rr2690.1
Publikováno v:
Radiation Research. 177:244-250
Radiation-induced bystander and abscopal effects, in which DNA damage is produced in nonirradiated cells as a consequence of communication with irradiated cells, indicate mechanisms of inducing damage and cell death additional to the conventional mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bca156b2f028f519841690bba3c5b82
https://doi.org/10.1667/rr2805.1
https://doi.org/10.1667/rr2805.1
Publikováno v:
Radiation Research. 177:18-24
Ionizing radiation is unequivocally leukemogenic and carcinogenic, and this is generally attributed to DNA damage arising as a consequence of deposition of energy in the cell nucleus at the time of exposure. However, nontargeted effects, in which DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fa4a98119bfc34ee411e2bc3a28242
https://doi.org/10.1667/rr2793.1
https://doi.org/10.1667/rr2793.1