Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Sally A. Little"'
Publikováno v:
Journal of Public Health Dentistry. 67:224-233
Objectives: To compare dental treatment experiences and costs in members of a health maintenance organization (HMO) in areas with and without community water fluoridation. Methods: HMO members with continuous dental eligibility (January 1, 1990 to De
Publikováno v:
Toxicological Sciences. 95:257-269
Hyperthermia (HS) and 4-hydroperoxycyclophosphamide (4CP) activate the mitochondrial apoptotic pathway in day 9 mouse embryos. Previous microarray analyses Microarray analyses revealed that several p53 target genes are upregulated after exposure to H
Publikováno v:
Birth Defects Research Part A: Clinical and Molecular Teratology. 67:98-107
BACKGROUND Using vital dyes, we have previously shown that while hyperthermia (HS), 4-hydroperoxycyclophosphamide (4CP), and staurosporine (ST) induce cell death within specific tissues (e.g., neuroepithelium) of day 9 mouse embryos, cells of the hea
Autor:
Philip E. Mirkes, Sally A. Little
Publikováno v:
Toxicology and Applied Pharmacology. 181:142-151
Previously we showed that teratogen-induced cell death in mouse embryos is apoptotic in nature, i.e., involves the release of cytochrome c from mitochondria and the subsequent activation of caspase-3, cleavage of poly (ADP-ribose) polymerase (PARP),
Autor:
Sally A. Little, Philip E. Mirkes
Publikováno v:
Toxicology and Applied Pharmacology. 162:197-206
Cell death is an early and common event in the pathogenesis associated with the abnormal development induced by a variety of teratogens. Previously, we showed that the cell death induced in day 9 mouse embryos by three teratogens, hyperthermia (HS),
Autor:
Sally A. Little, Philip E. Mirkes
Publikováno v:
Cell Death & Differentiation. 5:592-600
Teratogen-induced cell death is a common event in the pathogenesis associated with tissues destined to be malformed. Although the importance of this cell death is recognized, little information is available concerning the biochemistry of teratogen-in
Autor:
Philip E. Mirkes, Frances H. Wright, Michael J. Welsh, Sally A. Little, Thu Na Ngo Laney, Leanne Cornel
Publikováno v:
Molecular Reproduction and Development. 45:276-284
Previously we reported that eight proteins were reproducibly induced in postimplantation rat embryos exposed to a brief heat shock (43 degrees C, 15 min). The major heat-inducible rat embryo protein has now been identified as heat shock protein 72 (H
Autor:
Sally A. Little, Linda J. McGuffee
Publikováno v:
The Anatomical Record. 246:279-292
Background The tunica media of the vascular wall is a composite material comprised of smooth muscle cells and fibrous and non-fibrous matrix proteins. Methods Using morphometric techniques, this study quantifies the cell and matrix composition of nor
Publikováno v:
Cell and Tissue Research. 281:187-196
Vascular smooth muscle cells are surrounded by a basal lamina containing an array of macromolecules: included among these are the laminins, a family of oligomeric glycoproteins composed of subunits encoded by different genes. In this study, we have u