Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Sally A Sharpe"'
Autor:
Isabel Nogueira, Martí Català, Andrew D. White, Sally A Sharpe, Jordi Bechini, Clara Prats, Cristina Vilaplana, Pere-Joan Cardona
Publikováno v:
Pathogens, Vol 12, Iss 2, p 236 (2023)
Tuberculosis (TB) is still a major worldwide health problem and models using non-human primates (NHP) provide the most relevant approach for vaccine testing. In this study, we analysed CT images collected from cynomolgus and rhesus macaques following
Externí odkaz:
https://doaj.org/article/69aaf39cd93a4d8c87eaa017f48fbc4e
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88149 (2014)
Tuberculosis (TB) remains a major global public health problem. The only vaccine, BCG, gives variable protection, especially in adults, so several new vaccines are in clinical trials. There are no correlates of protective immunity to TB; therefore va
Externí odkaz:
https://doaj.org/article/28a50452a964413ca13a01becd5b6ace
Autor:
Rachel Tanner, Andrew D. White, Charelle Boot, Claudia C. Sombroek, Matthew K. O’Shea, Daniel Wright, Emily Hoogkamer, Julia Bitencourt, Stephanie A. Harris, Charlotte Sarfas, Rachel Wittenberg, Iman Satti, Helen A. Fletcher, Frank A. W. Verreck, Sally A. Sharpe, Helen McShane
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-11 (2021)
Abstract We present a non-human primate mycobacterial growth inhibition assay (MGIA) using in vitro blood or cell co-culture with the aim of refining and expediting early tuberculosis vaccine testing. We have taken steps to optimise the assay using c
Externí odkaz:
https://doaj.org/article/68af0e0e83b24984a10595f180e34dba
Autor:
Julia Bitencourt, Marco Polo Peralta-Álvarez, Morven Wilkie, Ashley Jacobs, Daniel Wright, Salem Salman Almujri, Shuailin Li, Stephanie A. Harris, Steven G. Smith, Sean C. Elias, Andrew D. White, Iman Satti, Sally S. Sharpe, Matthew K. O’Shea, Helen McShane, Rachel Tanner
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Tuberculosis (TB) is a major global health problem and the only currently-licensed vaccine, BCG, is inadequate. Many TB vaccine candidates are designed to be given as a boost to BCG; an understanding of the BCG-induced immune response is therefore cr
Externí odkaz:
https://doaj.org/article/048b6deb508042c9b23e2a2b29903bc3
Autor:
Laura Hunter, Suzie Hingley-Wilson, Graham R. Stewart, Sally A. Sharpe, Francisco Javier Salguero
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Non-human primate models of Tuberculosis (TB) are one of the most commonly used within the experimental TB field because they closely mimic the whole spectrum of disease progression of human TB. However, the early cellular interactions of the pulmona
Externí odkaz:
https://doaj.org/article/458ae1b2dfd74ac595bda6395ebe66fe
Autor:
Charlotte Sarfas, Andrew D. White, Laura Sibley, Alexandra L. Morrison, Jennie Gullick, Steve Lawrence, Mike J. Dennis, Philip D. Marsh, Helen A. Fletcher, Sally A. Sharpe
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In many countries where tuberculosis (TB) is endemic, the Bacillus Calmette–Guérin (BCG) vaccine is given as close to birth as possible to protect infants and children from severe forms of TB. However, BCG has variable efficacy and is not as effec
Externí odkaz:
https://doaj.org/article/23a524431d8548a983dc1bcc98994a67
Autor:
Rachel Tanner, Emily Hoogkamer, Julia Bitencourt, Andrew White, Charelle Boot, Claudia C. Sombroek, Stephanie A. Harris, Matthew K. O'Shea, Daniel Wright, Rachel Wittenberg, Charlotte Sarfas, Iman Satti, Frank A.W. Verreck, Sally A. Sharpe, Helen A. Fletcher, Helen McShane
Publikováno v:
F1000Research, Vol 10 (2021)
The only currently available approach to early efficacy testing of tuberculosis (TB) vaccine candidates is in vivo preclinical challenge models. These typically include mice, guinea pigs and non-human primates (NHPs), which must be exposed to virulen
Externí odkaz:
https://doaj.org/article/f4d160f312314877839761de896f12a2
Autor:
Rachel Tanner, Emily Hoogkamer, Julia Bitencourt, Andrew White, Charelle Boot, Claudia C. Sombroek, Stephanie A. Harris, Matthew K. O'Shea, Daniel Wright, Rachel Wittenberg, Charlotte Sarfas, Iman Satti, Frank A.W. Verreck, Sally A. Sharpe, Helen A. Fletcher, Helen McShane
Publikováno v:
F1000Research, Vol 10 (2021)
The only currently available approach to early efficacy testing of tuberculosis (TB) vaccine candidates is in vivo preclinical challenge models. These typically include mice, guinea pigs and non-human primates (NHPs), which must be exposed to virulen
Externí odkaz:
https://doaj.org/article/8d457b8383a642419000e0f51934d0e4
Autor:
Paula Ruibal, Kees L. M. C. Franken, Krista E. van Meijgaarden, Marjolein van Wolfswinkel, Ian Derksen, Ferenc A. Scheeren, George M. C. Janssen, Peter A. van Veelen, Charlotte Sarfas, Andrew D. White, Sally A. Sharpe, Fabrizio Palmieri, Linda Petrone, Delia Goletti, Thomas Abeel, Tom H. M. Ottenhoff, Simone A. Joosten
Publikováno v:
Journal of Immunology, 209(8)
The Journal of Immunology, 209(8), 1555-1565. AMER ASSOC IMMUNOLOGISTS
The Journal of Immunology, 209(8), 1555-1565. AMER ASSOC IMMUNOLOGISTS
Tuberculosis (TB) remains one of the deadliest infectious diseases worldwide, posing great social and economic burden to affected countries. Novel vaccine approaches are needed to increase protective immunity against the causative agent Mycobacterium
Autor:
Laura, Hunter, Suzie, Hingley-Wilson, Graham R, Stewart, Sally A, Sharpe, Francisco Javier, Salguero
Publikováno v:
Frontiers in Immunology
Non-human primate models of Tuberculosis (TB) are one of the most commonly used within the experimental TB field because they closely mimic the whole spectrum of disease progression of human TB. However, the early cellular interactions of the pulmona