IRAG2 Interacts with IP3-Receptor Types 1, 2, and 3 and Regulates Intracellular Ca2+ in Murine Pancreatic Acinar Cells

Autor: Rainer Schreiber, Jens Schlossmann, Sally Prüschenk, Michael Majer

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 13409, p 13409 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13409

The inositol 1,4,5-triphosphate receptor-associated 2 (IRAG2) is also known as Jaw1 or lymphoid-restricted membrane protein (LRMP) and shares homology with the inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate 1 (IRAG1). IRAG1 int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a3337ce4282087705facb083fa2630
https://epub.uni-regensburg.de/52039/

Activation of soluble guanylyl cyclase signalling with cinaciguat improves impaired kidney function in diabetic mice

Autor: Sally Prüschenk, Manuela Harloff, Roland Seifert, Jens Schlossmann

Diabetic nephropathy is the leading cause for end-stage renal disease worldwide. Until now, there is no specific therapy available. Standard treatment with inhibitors of the renin-angiotensin system just slows down progression. However, targeting the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c0074d9b3328db23fc2e43875cac47
https://epub.uni-regensburg.de/47906/