Microfluidic qPCR for detection of 21 common respiratory viruses in children with influenza-like illness.

Autor: Saville TJ; Division of Clinical Medicine, School of Medicine and Population Health, The University of Sheffield, Sheffield, UK. t.j.saville@sheffield.ac.uk.; NIHR Sheffield Biomedical Research Centre (BRC) and The Florey Institute of Infection, The University of Sheffield, Sheffield, UK. t.j.saville@sheffield.ac.uk., Colton H; Division of Clinical Medicine, School of Medicine and Population Health, The University of Sheffield, Sheffield, UK. h.colton@sheffield.ac.uk.; NIHR Sheffield Biomedical Research Centre (BRC) and The Florey Institute of Infection, The University of Sheffield, Sheffield, UK. h.colton@sheffield.ac.uk.; Department of Virology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK. h.colton@sheffield.ac.uk., Jarju S; Vaccines and Immunity Theme, Medical Research Council Unit The Gambia at the London, School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia., Armitage EP; Vaccines and Immunity Theme, Medical Research Council Unit The Gambia at the London, School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia.; Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK., Drammeh S; Vaccines and Immunity Theme, Medical Research Council Unit The Gambia at the London, School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia., Tazzyman S; Department of Virology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Jagne YJ; Vaccines and Immunity Theme, Medical Research Council Unit The Gambia at the London, School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia., Sallah HJ; Vaccines and Immunity Theme, Medical Research Council Unit The Gambia at the London, School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia., Senghore E; Vaccines and Immunity Theme, Medical Research Council Unit The Gambia at the London, School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia., Evans CM; Division of Clinical Medicine, School of Medicine and Population Health, The University of Sheffield, Sheffield, UK.; NIHR Sheffield Biomedical Research Centre (BRC) and The Florey Institute of Infection, The University of Sheffield, Sheffield, UK.; Department of Virology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK., Darton TC; Division of Clinical Medicine, School of Medicine and Population Health, The University of Sheffield, Sheffield, UK.; NIHR Sheffield Biomedical Research Centre (BRC) and The Florey Institute of Infection, The University of Sheffield, Sheffield, UK., de Silva TI; Division of Clinical Medicine, School of Medicine and Population Health, The University of Sheffield, Sheffield, UK.; NIHR Sheffield Biomedical Research Centre (BRC) and The Florey Institute of Infection, The University of Sheffield, Sheffield, UK.; Vaccines and Immunity Theme, Medical Research Council Unit The Gambia at the London, School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia.; Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.

Publikováno v: Scientific reports [Sci Rep] 2024 Nov 16; Vol. 14 (1), pp. 28292. Date of Electronic Publication: 2024 Nov 16.

Systemic prime mucosal boost significantly increases protective efficacy of bivalent RSV influenza viral vectored vaccine.

Autor: Bissett C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK. cameron.bissett@linacre.ox.ac.uk., Belij-Rammerstorfer S; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Ulaszewska M; Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Smith H; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Kailath R; Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Morris S; Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Powers C; Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Sebastian S; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Sharpe HR; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Allen ER; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Wang Z; Department of Infectious Disease, Imperial College London, London, UK., Cunliffe RF; Department of Infectious Disease, Imperial College London, London, UK., Sallah HJ; Department of Infectious Disease, Imperial College London, London, UK., Spencer AJ; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia., Gilbert S; Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Tregoning JS; Department of Infectious Disease, Imperial College London, London, UK., Lambe T; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.

Publikováno v: NPJ vaccines [NPJ Vaccines] 2024 Jun 26; Vol. 9 (1), pp. 118. Date of Electronic Publication: 2024 Jun 26.

Streptococcus pyogenes Colonization in Children Aged 24-59 Months in the Gambia: Impact of Live Attenuated Influenza Vaccine and Associated Serological Responses.

Autor: Keeley AJ; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.; Department of Infection, Immunity, and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, United Kingdom.; Vaccines and Immunity Theme, Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia., Groves D; Department of Infection, Immunity, and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, United Kingdom., Armitage EP; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.; Vaccines and Immunity Theme, Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia., Senghore E; Vaccines and Immunity Theme, Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia., Jagne YJ; Vaccines and Immunity Theme, Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia., Sallah HJ; Vaccines and Immunity Theme, Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia., Drammeh S; Vaccines and Immunity Theme, Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia., Angyal A; Department of Infection, Immunity, and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, United Kingdom., Hornsby H; Department of Infection, Immunity, and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, United Kingdom., de Crombrugghe G; Molecular Bacteriology Laboratory, Université Libre de Bruxelles, Brussels, Belgium.; Department of Pediatrics, Hôpital Universitaire des Enfants Reine Fabiola, Université Libre de Bruxelles Brussels, Belgium., Smeesters PR; Molecular Bacteriology Laboratory, Université Libre de Bruxelles, Brussels, Belgium.; Department of Pediatrics, Hôpital Universitaire des Enfants Reine Fabiola, Université Libre de Bruxelles Brussels, Belgium., Rossi O; GSK Vaccines Institute for Global Health, Siena, Italy., Carducci M; GSK Vaccines Institute for Global Health, Siena, Italy., Peno C; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom., Bogaert D; Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom., Kampmann B; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.; Vaccines and Immunity Theme, Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.; Charité Centre for Global Health and Institut für Internationale Gesundheit, Charité - Universitätsmedizin Berlin, Berlin, Germany., Marks M; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.; Hospital for Tropical Diseases, University College London Hospital, London, United Kingdom.; Division of Infection and Immunity, University College London, London, United Kingdom., Shaw HA; Vaccines Division, Scientific Research and Innovation Group, Medicines and Healthcare Products Regulatory Agency, Potters Bar, United Kingdom., Turner CR; School of Biosciences, University of Sheffield, Sheffield, United Kingdom., de Silva TI; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.; Department of Infection, Immunity, and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, United Kingdom.; Vaccines and Immunity Theme, Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.

Publikováno v: The Journal of infectious diseases [J Infect Dis] 2023 Oct 03; Vol. 228 (7), pp. 957-965.

Prior upregulation of interferon pathways in the nasopharynx impacts viral shedding following live attenuated influenza vaccine challenge in children.

Autor: Costa-Martins AG; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.; Scientific Platform Pasteur, University of São Paulo, São Paulo, Brazil., Mane K; Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, P.O. Box 273, Fajara, The Gambia., Lindsey BB; The Florey Institute for Host-Pathogen Interactions and Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield S10 2RX, UK., Ogava RLT; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil., Castro Í; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil., Jagne YJ; Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, P.O. Box 273, Fajara, The Gambia., Sallah HJ; Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, P.O. Box 273, Fajara, The Gambia., Armitage EP; Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, P.O. Box 273, Fajara, The Gambia., Jarju S; Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, P.O. Box 273, Fajara, The Gambia., Ahadzie B; Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, P.O. Box 273, Fajara, The Gambia., Ellis-Watson R; The University of Edinburgh/MRC Centre for Inflammation Research, The Queen's Medical Research Institute, Edinburgh EH16 4TJ, UK., Tregoning JS; Department of Infectious Disease, Imperial College London, London W2 1NY, UK., Bingle CD; The Florey Institute for Host-Pathogen Interactions and Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield S10 2RX, UK., Bogaert D; The University of Edinburgh/MRC Centre for Inflammation Research, The Queen's Medical Research Institute, Edinburgh EH16 4TJ, UK., Clarke E; Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, P.O. Box 273, Fajara, The Gambia., Ordovas-Montanes J; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA 02115, USA.; Program in Immunology, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Harvard Stem Cell Institute, Cambridge, MA 02138, USA., Jeffries D; Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, P.O. Box 273, Fajara, The Gambia., Kampmann B; Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, P.O. Box 273, Fajara, The Gambia.; The Vaccine Centre, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK., Nakaya HI; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.; Scientific Platform Pasteur, University of São Paulo, São Paulo, Brazil., de Silva TI; Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, P.O. Box 273, Fajara, The Gambia.; The Florey Institute for Host-Pathogen Interactions and Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield S10 2RX, UK.

Publikováno v: Cell reports. Medicine [Cell Rep Med] 2021 Dec 09; Vol. 2 (12), pp. 100465. Date of Electronic Publication: 2021 Dec 09 (Print Publication: 2021).