Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Salla M Kangas"'
Autor:
Viivi Järvelä, Mira Hamze, Jonna Komulainen-Ebrahim, Elisa Rahikkala, Johanna Piispala, Mika Kallio, Salla M. Kangas, Tereza Nickl, Marko Huttula, Reetta Hinttala, Johanna Uusimaa, Igor Medina, Esa-Ville Immonen
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
The potassium-chloride co-transporter 2, KCC2, is a neuron-specific ion transporter that plays a multifunctional role in neuronal development. In mature neurons, KCC2 maintains a low enough intracellular chloride concentration essential for inhibitor
Externí odkaz:
https://doaj.org/article/c924fe7976664232b84b934d595bc41c
Autor:
Flavia Scoyni, Valeriia Sitnikova, Luca Giudice, Paula Korhonen, Davide M. Trevisan, Ana Hernandez de Sande, Mireia Gomez-Budia, Raisa Giniatullina, Irene F. Ugidos, Hiramani Dhungana, Cristiana Pistono, Nea Korvenlaita, Nelli-Noora Välimäki, Salla M. Kangas, Anniina E. Hiltunen, Emma Gribchenko, Minna U. Kaikkonen-Määttä, Jari Koistinaho, Seppo Ylä-Herttuala, Reetta Hinttala, Morten T. Venø, Junyi Su, Markus Stoffel, Anne Schaefer, Nikolaus Rajewsky, Jørgen Kjems, Mary P. LaPierre, Monika Piwecka, Jukka Jolkkonen, Rashid Giniatullin, Thomas B. Hansen, Tarja Malm
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113862- (2024)
Summary: Brain functionality relies on finely tuned regulation of gene expression by networks of non-coding RNAs (ncRNAs) such as the one composed by the circular RNA ciRS-7 (also known as CDR1as), the microRNA miR-7, and the long ncRNA Cyrano. We de
Externí odkaz:
https://doaj.org/article/3f5181ebf602423b89fa5aca16a2796d
Autor:
Paula L. Keskitalo, Salla M. Kangas, Sirja Sard, Tytti Pokka, Virpi Glumoff, Petri Kulmala, Paula Vähäsalo
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 20, Iss 1, Pp 1-9 (2022)
Abstract Objective The aim of this study was to analyze the usefulness of myeloid-related protein 8/14 (MRP8/14) in the prediction of disease course in a real-world setting for patients with new-onset juvenile idiopathic arthritis (JIA), to identify
Externí odkaz:
https://doaj.org/article/99232d67ab124ccd88c0dee157169d67
Autor:
Salla M. Kangas, Jaakko Teppo, Maija J. Lahtinen, Anu Suoranta, Bishwa Ghimire, Pirkko Mattila, Johanna Uusimaa, Markku Varjosalo, Jani Katisko, Reetta Hinttala
Publikováno v:
Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-16 (2022)
Abstract Background Transcriptomic and proteomic profiling of human brain tissue is hindered by the availability of fresh samples from living patients. Postmortem samples usually represent the advanced disease stage of the patient. Furthermore, the p
Externí odkaz:
https://doaj.org/article/01bcf4d50e8f47fa87519123d6cba3ff
Autor:
Anniina E. Hiltunen, Salla M. Kangas, Steffen Ohlmeier, Ilkka Pietilä, Jori Hiltunen, Heikki Tanila, Colin McKerlie, Subashika Govindan, Hannu Tuominen, Riitta Kaarteenaho, Mikko Hallman, Johanna Uusimaa, Reetta Hinttala
Publikováno v:
Molecular Medicine, Vol 26, Iss 1, Pp 1-16 (2020)
Abstract Background FINCA disease is a pediatric cerebropulmonary disease caused by variants in the NHL repeat-containing 2 (NHLRC2) gene. Neurological symptoms are among the first manifestations of FINCA disease, but the consequences of NHLRC2 defic
Externí odkaz:
https://doaj.org/article/49cbc6b319124640b45364e90fbbfc8c
Autor:
Tomáš Zárybnický, Anne Heikkinen, Salla M. Kangas, Marika Karikoski, Guillermo Antonio Martínez-Nieto, Miia H. Salo, Johanna Uusimaa, Reetta Vuolteenaho, Reetta Hinttala, Petra Sipilä, Satu Kuure
Publikováno v:
Cells, Vol 10, Iss 11, p 3158 (2021)
The modification of genes in animal models has evidently and comprehensively improved our knowledge on proteins and signaling pathways in human physiology and pathology. In this review, we discuss almost 40 monogenic rare diseases that are enriched i
Externí odkaz:
https://doaj.org/article/51145108edac43eaa2eb4993dd172c41
Autor:
Flavia Scoyni, Valeriia Sitnikova, Luca Giudice, Paula Korhonen, Davide M Trevisan, Ana Hernandez de Sande, Mireia Gomez-Budia, Raisa Giniatullina, Irene F Ugidos, Hiramani Dhungana, Cristiana Pistono, Nea Korvenlaita, Nelli-Noora Välimäki, Salla M Kangas, Anniina E Hiltunen, Minna U Kaikkonen-Määttä, Jari Koistinaho, Seppo Ylä-Herttuala, Reetta Hinttala, Morten T Venø, Junyi Su, Markus Stoffel, Anne Schaefer, Nikolaus Rajewsky, Jørgen Kjems, Mary P LaPierre, Monika Piwecka, Jukka Jolkkonen, Rashid Giniatullin, Thomas B Hansen, Malm Tarja
Brain functionality resides on finely tuned regulation of gene expression by networks of non-coding RNAs (ncRNAs) such as the one composed by the circular RNA ciRS-7, the microRNA miR-7 and the long non-coding RNA Cyrano. However, very little is know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3e1bb4b25620fb6dfa176ceecb3a6d4
https://doi.org/10.1101/2023.01.24.525136
https://doi.org/10.1101/2023.01.24.525136
Autor:
Maria Suo-Palosaari, Päivi Vieira, Elisa Rahikkala, Oula Knuutinen, Reetta Hinttala, Johanna Uusimaa, Salla M. Kangas, Jukka S. Moilanen, Jaakko H Oikarainen, Tytti Pokka
Publikováno v:
Developmental Medicine & Child Neurology. 63:1066-1074
AIM To examine the epidemiological, clinical, and genetic characteristics of paediatric patients with genetic white matter disorders (GWMDs) in Northern Finland. METHOD A longitudinal population-based cohort study was conducted in the tertiary catchm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2166b514d2ef530b97d0d5e656058203
https://doi.org/10.1111/dmcn.14884
https://doi.org/10.1111/dmcn.14884
Autor:
Paula L Keskitalo, Salla M Kangas, Sirja Sard, Tytti Pokka, Virpi Glumoff, Petri Kulmala, Paula Vähäsalo
Objective: The aim of this study was to analyze the usefulness of myeloid-related protein 8/14 (MRP8/14) in the prediction of disease course in a real-life setting for patients with new-onset juvenile idiopathic arthritis (JIA), to identify the relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02d15195dd7e441a358a90aacb480aed
https://doi.org/10.21203/rs.3.rs-1246533/v1
https://doi.org/10.21203/rs.3.rs-1246533/v1
Autor:
Salla M, Kangas, Jaakko, Teppo, Maija J, Lahtinen, Anu, Suoranta, Bishwa, Ghimire, Pirkko, Mattila, Johanna, Uusimaa, Markku, Varjosalo, Jani, Katisko, Reetta, Hinttala
Publikováno v:
Translational neurodegeneration. 11(1)
Transcriptomic and proteomic profiling of human brain tissue is hindered by the availability of fresh samples from living patients. Postmortem samples usually represent the advanced disease stage of the patient. Furthermore, the postmortem interval c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4dff067fdac6a399eaf7835d4fedab7c
https://pubmed.ncbi.nlm.nih.gov/35418104
https://pubmed.ncbi.nlm.nih.gov/35418104