Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Salla I. Virtanen"'
Autor:
Hannes M. Beyer, Salla I. Virtanen, A. Sesilja Aranko, Kornelia M. Mikula, George T. Lountos, Alexander Wlodawer, O. H. Samuli Ollila, Hideo Iwaï
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8367 (2020)
Protein splicing catalyzed by inteins utilizes many different combinations of amino-acid types at active sites. Inteins have been classified into three classes based on their characteristic sequences. We investigated the structural basis of the prote
Externí odkaz:
https://doaj.org/article/8e51ad775d27471584c9fd0e0da0bc18
Autor:
Matti Javanainen, Salla I. Virtanen, Fernando Favela-Rosales, Chris Papadopoulos, Antonio Peón, Amélie Bacle, Anne M. Kiirikki, Patrick F.J. Fuchs, O. H. Samuli Ollila, Pavel Buslaev, Ángel Piñeiro, Rebeca García-Fandiño, Paula Milán Rodríguez, Tiago Mendes Ferreira, Markus S. Miettinen, Jesper J. Madsen, Josef Melcr, Ivan Gushchin, Thomas J. Piggot
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, 2021, 143 (34), pp.13701-13709. ⟨10.1021/jacs.1c05549⟩
Journal of the American Chemical Society, 143(34), 13701-13709. AMER CHEMICAL SOC
Journal of the American Chemical Society, American Chemical Society, 2021, 143 (34), pp.13701-13709. ⟨10.1021/jacs.1c05549⟩
Journal of the American Chemical Society, 2021, 143 (34), pp.13701-13709. ⟨10.1021/jacs.1c05549⟩
Journal of the American Chemical Society, 143(34), 13701-13709. AMER CHEMICAL SOC
Journal of the American Chemical Society, American Chemical Society, 2021, 143 (34), pp.13701-13709. ⟨10.1021/jacs.1c05549⟩
International audience; Interest in lipid interactions with proteins and other biomolecules is emerging not only in fundamental biochemistry but also in the field of nanobiotechnology where lipids are commonly used, for example, in carriers of mRNA v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d9345531ed2d3d157ba5bfda9d2f8b
https://hal.sorbonne-universite.fr/hal-03355166/file/jacs.1c05549.pdf
https://hal.sorbonne-universite.fr/hal-03355166/file/jacs.1c05549.pdf
Autor:
George T. Lountos, Hideo Iwaï, Hannes M. Beyer, Kornelia M. Mikula, O. H. Samuli Ollila, Alexander Wlodawer, Salla I. Virtanen, A. Sesilja Aranko
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8367, p 8367 (2020)
'International Journal of Molecular Sciences ', vol: 21, pages: 8367-1-8367-20 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 21
'International Journal of Molecular Sciences ', vol: 21, pages: 8367-1-8367-20 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 21
Protein splicing catalyzed by inteins utilizes many different combinations of amino-acid types at active sites. Inteins have been classified into three classes based on their characteristic sequences. We investigated the structural basis of the prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2481d429fcb60ec905457461052700ee
https://www.mdpi.com/1422-0067/21/21/8367
https://www.mdpi.com/1422-0067/21/21/8367
Publikováno v:
Physical chemistry chemical physics : PCCP. 22(37)
Importance of disordered protein regions is increasingly recognized in biology, but their characterization remains challenging due to the lack of suitable experimental and theoretical methods. NMR experiments can detect multiple timescale dynamics an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f954b7dc8f00f1ac1ef52f3fd02106d1
https://pubmed.ncbi.nlm.nih.gov/32929427
https://pubmed.ncbi.nlm.nih.gov/32929427
Autor:
George T. Lountos, Hideo Iwaï, Hannes M. Beyer, O. H. S. Ollila, Salla I. Virtanen, A.S. Aranko, Alexander Wlodawer, Kornelia M. Mikula
The widely used molecular evolutionary clock assumes the divergent evolution of proteins. Convergent evolution has been proposed only for small protein elements but not for an entire protein fold. We investigated the structural basis of the protein s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f41fe63841d00cddcccbf95b67dd6b0d
Autor:
Christopher P. Landowski, Wolfgang J. Fischer, Merja Penttilä, Quan Zhou, Markus Linder, Laura Lemetti, Pezhman Mohammadi, Salla I. Virtanen, A. Sesilja Aranko, Zoran Cenev, Wolfgang Wagermaier
Publikováno v:
Communications Biology
Mohammadi, P, Aranko, A S, Lemetti, L, Cenev, Z, Zhou, Q, Virtanen, S, Landowski, C P, Penttilä, M, Fischer, W J, Wagermaier, W & Linder, M B 2018, ' Phase transitions as intermediate steps in the formation of molecularly engineered protein fibers ', Communications biology, vol. 1, 86, pp. 86 . https://doi.org/10.1038/s42003-018-0090-y
Communications Biology, Vol 1, Iss 1, Pp 1-12 (2018)
Mohammadi, P, Aranko, A S, Lemetti, L, Cenev, Z, Zhou, Q, Virtanen, S, Landowski, C P, Penttilä, M, Fischer, W J, Wagermaier, W & Linder, M B 2018, ' Phase transitions as intermediate steps in the formation of molecularly engineered protein fibers ', Communications biology, vol. 1, 86, pp. 86 . https://doi.org/10.1038/s42003-018-0090-y
Communications Biology, Vol 1, Iss 1, Pp 1-12 (2018)
A central concept in molecular bioscience is how structure formation at different length scales is achieved. Here we use spider silk protein as a model to design new recombinant proteins that assemble into fibers. We made proteins with a three-block
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1ed364564415649cfaebf07ab7ad844
https://hdl.handle.net/21.11116/0000-0001-AA81-D21.11116/0000-0001-AA83-B
https://hdl.handle.net/21.11116/0000-0001-AA81-D21.11116/0000-0001-AA83-B
Autor:
Claude P. Muller, Jens Desloovere, Dmitrii Bychkov, Xavier Saelens, Linda L. Theisen, Oxana V. Denisova, Vladislav V. Verkhusha, Sampsa Matikainen, Elena Vashchinkina, Olli Kallioniemi, Sandra Söderholm, Ilkka Julkunen, Tuula A. Nyman, Janne Tynell, Denis E. Kainov, Carina von Schantz, Niina Ikonen, Salla I. Virtanen
Publikováno v:
Antimicrobial agents and chemotherapy. 58(7)
The influenza pH1N1 virus caused a global flu pandemic in 2009 and continues manifestation as a seasonal virus. Better understanding of the virus-host cell interaction could result in development of better prevention and treatment options. Here we sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870ae4197aeaa400e38053905d28ff40
https://pubmed.ncbi.nlm.nih.gov/24752266
https://pubmed.ncbi.nlm.nih.gov/24752266
Publikováno v:
De novo Molecular Design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::723091c5be73f56bfc5a407724a4838f
https://doi.org/10.1002/9783527677016.ch13
https://doi.org/10.1002/9783527677016.ch13
Autor:
Olli T. Pentikäinen, Sanna Niinivehmas, Jukka V. Lehtonen, Pekka A. Postila, Salla I. Virtanen
Publikováno v:
Journal of chemical information and modeling. 51(6)
Reliable and effective virtual high-throughput screening (vHTS) methods are desperately needed to minimize the expenses involved in drug discovery projects. Here, we present an improvement to the negative image-based (NIB) screening: the shape, the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a444e3ef120e2042209b289ee0f4fda4
https://pubmed.ncbi.nlm.nih.gov/21591817
https://pubmed.ncbi.nlm.nih.gov/21591817
Autor:
Olli T. Pentikäinen, Salla I. Virtanen
Publikováno v:
Journal of chemical information and modeling. 50(6)
The protein structure-based virtual screening is typically accomplished using a molecular docking procedure. However, docking is a fairly slow process that is limited by the available scoring functions that cannot reliably distinguish between active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050ab471c42900e5dd4f58a9ba2a98b0
https://pubmed.ncbi.nlm.nih.gov/20504004
https://pubmed.ncbi.nlm.nih.gov/20504004