Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Salix, Boulet"'
Publikováno v:
Current Research in Immunology, Vol 3, Iss , Pp 23-36 (2022)
The myeloid cellular compartment comprises monocytes, dendritic cells (DCs), macrophages and granulocytes. As diverse as this group of cells may be, they are all an important part of the innate immune system and are therefore linked by the necessity
Externí odkaz:
https://doaj.org/article/439f823f70ca46ce8a110d805abb2789
Autor:
Valérie Janelle, Mathieu Neault, Marie-Ève Lebel, Dave Maurice De Sousa, Salix Boulet, Ludovic Durrieu, Cédric Carli, Chloé Muzac, Sébastien Lemieux, Nathalie Labrecque, Heather J. Melichar, Frédérick A. Mallette, Jean-Sébastien Delisle
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
T-cell dysfunction arising upon repeated antigen exposure prevents effective immunity and immunotherapy. Using various clinically and physiologically relevant systems, we show that a prominent feature of PD-1-expressing exhausted T cells is the devel
Externí odkaz:
https://doaj.org/article/1007f9fb6e534841863c22c013ae6191
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2021)
The nuclear orphan receptors NR4A1, NR4A2, and NR4A3 are immediate early genes that are induced by various signals. They act as transcription factors and their activity is not regulated by ligand binding and are thus regulated via their expression le
Externí odkaz:
https://doaj.org/article/03949a52b63b471bba0a3bf6b203e4cf
Autor:
Valérie Janelle, Mathieu Neault, Marie-Eve Lebel, Dave De Sousa, Salix Boulet, Ludovic Durrieu, Cedric Carli, Sebastien Lemieux, Nathalie Labrecque, Heather Melichar, Frederick Mallette, Jean-Sebastien Delisle
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/52c78fe87ac64d1399810f892f4f2e4e
Autor:
Dave Maurice De Sousa, Frédéric Duval, Jean-François Daudelin, Salix Boulet, Nathalie Labrecque
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215012 (2019)
During CD8+ T cell response, Notch signaling controls short-lived-effector-cell (SLEC) generation, but the exact mechanisms by which it does so remains unclear. The Notch signaling pathway can act as a key regulator of Akt signaling via direct transc
Externí odkaz:
https://doaj.org/article/af6e3de0e682405f879d19bc9990e57f
Autor:
Miriam Marquis, Salix Boulet, Simon Mathien, Justine Rousseau, Paméla Thébault, Jean-François Daudelin, Julie Rooney, Benjamin Turgeon, Claudine Beauchamp, Sylvain Meloche, Nathalie Labrecque
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86681 (2014)
The classical mitogen-activated protein kinases (MAPKs) ERK1 and ERK2 are activated upon stimulation of cells with a broad range of extracellular signals (including antigens) allowing cellular responses to occur. ERK3 is an atypical member of the MAP
Externí odkaz:
https://doaj.org/article/bf49f1204adc4e9a90c201b2691e7067
Autor:
Nathalie Labrecque, Mathieu Neault, Dave Maurice De Sousa, Ludovic Durrieu, Salix Boulet, Frédérick A. Mallette, Jean-Sébastien Delisle, Sébastien Lemieux, Cedric Carli, Heather J. Melichar, Valérie Janelle, Marie-Ève Lebel
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background The development of immunotherapies holds great promise for the treatment of refractory infections and cancer. Current approaches, although effective in many settings, have limitations that prevent their widespread use. Hence, several aspec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c064826ebeb9fed72070d31620a73b83
https://doaj.org/article/52c78fe87ac64d1399810f892f4f2e4e
https://doaj.org/article/52c78fe87ac64d1399810f892f4f2e4e
Autor:
Sandrine Nicolas, Dave Maurice De Sousa, Salix Boulet, Nathalie Labrecque, Livia Odagiu, Jean François Daudelin
Publikováno v:
Proc Natl Acad Sci U S A
Enhancing long-term persistence while simultaneously potentiating the effector response of CD8(+) T cells has been a long-standing goal in immunology to produce better vaccines and adoptive cell therapy products. NR4A3 is a transcription factor of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a342ce51ff0876442a4906123b10042a
https://europepmc.org/articles/PMC7533658/
https://europepmc.org/articles/PMC7533658/
Autor:
Mélissa Mathieu, Natacha Cotta-Grand, Jean-François Daudelin, Salix Boulet, Réjean Lapointe, Nathalie Labrecque
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30139 (2012)
The identification of the signals that should be provided by antigen-presenting cells (APCs) to induce a CD8(+) T cell response in vivo is essential to improve vaccination strategies using antigen-loaded APCs. Although dendritic cells have been exten
Externí odkaz:
https://doaj.org/article/91e852c2b4a5496db91c145bf8a29c82
Autor:
Heather J. Melichar, Mengqi Dong, Marie-Ève Lebel, Salix Boulet, Nathalie Labrecque, Jean-François Daudelin, Livia Odagiu
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 207(4)
Central tolerance aims to limit the production of T lymphocytes bearing TCR with high affinity for self-peptide presented by MHC molecules. The accumulation of thymocytes with such receptors is limited by negative selection or by diversion into alter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80864cc54bde0642744db3e3fbcc4322
https://pubmed.ncbi.nlm.nih.gov/34373284
https://pubmed.ncbi.nlm.nih.gov/34373284