Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Salima Hacein‐Bey‐Abina"'
Autor:
Alain E. Andrea, Andrada Chiron, Guillaume Sarrabayrouse, Stéphanie Bessoles, Salima Hacein-Bey-Abina
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
In recent years, following the groundbreaking achievements of chimeric antigen receptor (CAR) T cell therapy in hematological cancers, and advancements in cell engineering technologies, the exploration of other immune cells has garnered significant a
Externí odkaz:
https://doaj.org/article/aa1b8a2a8ddf4e649776d6b5e057e544
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/d80ba68194f845f7813e0b6aeb46fb6d
Autor:
Hai Doan Do, Corinne Marie, Stéphanie Bessoles, Hélène Dhotel, Johanne Seguin, Benoit Larrat, Bich-Thuy Doan, Daniel Scherman, Virginie Escriou, Salima Hacein-Bey-Abina, Nathalie Mignet
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 3, Iss 3, Pp 398-413 (2022)
Aim: Gene-based immunotherapy against cancer is limited by low gene transfer efficiency. In the literature, interleukin-12 (IL-12) encoding plasmid associated with sonoporation has been shown to enhance antitumoral activity. Moreover, non-viral carr
Externí odkaz:
https://doaj.org/article/755a37e131c8442190d977af4f4c1990
Autor:
Julianne Duhazé, Miguel Caubet, Signe Hässler, Delphine Bachelet, Matthieu Allez, Florian Deisenhammer, Anna Fogdell-Hahn, Aude Gleizes, Salima Hacein-Bey-Abina, Xavier Mariette, Marc Pallardy, Philippe Broët, on behalf of the ABIRISK Consortium
Publikováno v:
BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background With the growth in use of biotherapic drugs in various medical fields, the occurrence of anti-drug antibodies represents nowadays a serious issue. This immune response against a drug can be due either to pre-existing antibodies or
Externí odkaz:
https://doaj.org/article/e376e3073012448d8b8de8a68028e116
Autor:
Alain E. Andrea, Andrada Chiron, Sarah Mallah, Stéphanie Bessoles, Guillaume Sarrabayrouse, Salima Hacein-Bey-Abina
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
During this last decade, adoptive transfer of T lymphocytes genetically modified to express chimeric antigen receptors (CARs) emerged as a valuable therapeutic strategy in hematological cancers. However, this immunotherapy has demonstrated limited ef
Externí odkaz:
https://doaj.org/article/bc0b3529ba29475f88a47269a5c030e7
Autor:
Michael Collins, Xavier Mariette, Raphaele Seror, Gaetane Nocturne, Franck Carbonnel, Aude Gleizes, Salima Hacein-Bey-Abina, Laurie Cachen, Antoine Meyer
Publikováno v:
RMD Open, Vol 8, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/e1c19d360a8c4ed7a1b7e426f578302f
Autor:
Sabine Charrier, Chantal Lagresle-Peyrou, Valentina Poletti, Michael Rothe, Grégory Cédrone, Bernard Gjata, Fulvio Mavilio, Alain Fischer, Axel Schambach, Jean-Pierre de Villartay, Marina Cavazzana, Salima Hacein-Bey-Abina, Anne Galy
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 15, Iss , Pp 232-245 (2019)
Genetic deficiency of the nuclease DCLRE1C/Artemis causes radiosensitive severe combined immunodeficiency (RS-SCID) with lack of peripheral T and B cells and increased sensitivity to ionizing radiations. Gene therapy based on transplanting autologous
Externí odkaz:
https://doaj.org/article/3824403f1c8443e1b57c5921ed3b19ae
Autor:
Philippe Horellou, Aliénor de Chalus, Laetitia Giorgi, Carole Leroy, Pascale Chrétien, Salima Hacein-Bey-Abina, Christine Bourgeois, Xavier Mariette, Ché Serguera, Roger Le Grand, Kumaran Deiva
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundMyelin oligodendrocytes glycoprotein (MOG) antibody-associated disease (MOGAD) represent 25% of pediatric acquired demyelinating syndrome (ADS); 40% of them may relapse, mimicking multiple sclerosis (MS), a recurrent and neurodegenerative A
Externí odkaz:
https://doaj.org/article/ad8652ab093d42bda4c0be6345f30bc4
Autor:
Julianne Duhazé, Signe Hässler, Delphine Bachelet, Aude Gleizes, Salima Hacein-Bey-Abina, Matthieu Allez, Florian Deisenhammer, Anna Fogdell-Hahn, Xavier Mariette, Marc Pallardy, Philippe Broët
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Predicting immunogenicity for biotherapies using patient and drug-related factors represents nowadays a challenging issue. With the growing ability to collect massive amount of data, machine learning algorithms can provide efficient predictive tools.
Externí odkaz:
https://doaj.org/article/46f1c812769c448fa17c62ce8e70ea24
Autor:
Erik L. Clarke, A. Jesse Connell, Emmanuelle Six, Nadia A. Kadry, Arwa A. Abbas, Young Hwang, John K. Everett, Casey E. Hofstaedter, Rebecca Marsh, Myriam Armant, Judith Kelsen, Luigi D. Notarangelo, Ronald G. Collman, Salima Hacein-Bey-Abina, Donald B. Kohn, Marina Cavazzana, Alain Fischer, David A. Williams, Sung-Yun Pai, Frederic D. Bushman
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-14 (2018)
Abstract Background Mutation of the IL2RG gene results in a form of severe combined immune deficiency (SCID-X1), which has been treated successfully with hematopoietic stem cell gene therapy. SCID-X1 gene therapy results in reconstitution of the prev
Externí odkaz:
https://doaj.org/article/3e61033ef32c4bfb98b5c61714518c31