Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Salim S. Sabri"'
Autor:
Ayman M. Saleh, Ahmad Aljada, Mustafa M. El-Abadelah, Mutasem O. Taha, Salim S. Sabri, Jalal A. Zahra, Mohammad Azhar Aziz
Publikováno v:
Cellular Physiology and Biochemistry, Vol 35, Iss 5, Pp 1943-1957 (2015)
Background/Aims: The antileukemic potential of isoindigos make them desired candidates for understanding their mechanism of action. We have recently synthesized a novel group of pyridone-annelated isoindigos and identified the derivative 5'-Cl that i
Externí odkaz:
https://doaj.org/article/828e6706d5b9498d8c97266bc4b9de08
Autor:
Ayman M. Saleh, Ahmad Aljada, Mustafa M. El-Abadelah, Salim S. Sabri, Jalal A. Zahra, Amre Nasr, Mohammad A. Aziz
Publikováno v:
Cellular Physiology and Biochemistry, Vol 35, Iss 5, Pp 1958-1974 (2015)
Background/Aims: In our quest to develop an isoindigo with improved efficacy and bioavailability, we recently synthesized a series of novel substituted pyridone-annelated isoindigo and evaluated their antiproliferative effects. We identified the comp
Externí odkaz:
https://doaj.org/article/b7ceffb93eb04401982e8506f8cc56be
Autor:
Ayman M. Saleh, Randa M. Al-As'ad, Mustafa M. El-Abadelah, Salim S. Sabri, Jalal A. Zahra, Ahmed S. Alaskar, Ahmad Aljada
Publikováno v:
Molecules, Vol 19, Iss 9, Pp 13076-13092 (2014)
A selected set of substituted pyridone-annelated isoindigos 3a–f has been synthesized via interaction of 5- and 6-substituted oxindoles 2a–f with 6-ethyl-1,2,9-trioxopyrrolo[3,2-f]quinoline-8-carboxylic acid (1) in acetic acid at reflux. Among th
Externí odkaz:
https://doaj.org/article/f70c9af71b1343bc9bb01d619b6be224
Publikováno v:
Molecules, Vol 12, Iss 8, Pp 1558-1568 (2007)
Substituted [1,4]thiazepino[2,3-h]quinolinecarboxylic acid 3 is prepared by PPA-catalyzed thermal lactamization of the respective 8-amino-7-[(2-carboxyethyl)thio]- 1,4-dihydroquinoline-3-carboxylic acid 9. The latter synthon is obtained by reduction
Externí odkaz:
https://doaj.org/article/4df16e5695f1490a99c3c416ea950fdd
Publikováno v:
Zeitschrift für Naturforschung C. 78:141-148
A series of novel 2-(quinolin-2-yl)-spiro[oxindole-3,3′-pyrrolines] were synthesized by one-pot three-component reaction involving dimethyl acetylenedicarboxylate, 1-phenylimidazo[1,5-a]quinoline and N-alkylisatins in chloroform at ∼60 °C for 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::546fa4310060a6f7dfab14d7a8c22db1
https://doi.org/10.1515/znc-2022-0085
https://doi.org/10.1515/znc-2022-0085
Autor:
Jalal A. Zahra, Mustafa M. El-Abadelah, Abdullah K. Jarrar, Salim S. Sabri, Mohammad S. Hamdan
Publikováno v:
Letters in Organic Chemistry. 19:976-982
Abstract: The preparation of 6-chloro-5-nitrothieno[3,2-e][1,3]thiazin-4-one incorporating 2-(Nmorpholinyl) moiety is achieved via a conventional route. Interaction of the latter substrate with a set of N'-(aryl) benzothiohydrazides 1a-f, in the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21c16b033441bd5c1278ff1c1a4fc96e
https://doi.org/10.2174/1570178619666220314151114
https://doi.org/10.2174/1570178619666220314151114
Autor:
Ahmad H, Abdullah, Jalal A, Zahra, Salim S, Sabri, Firas F, Awwadi, Ahmad Q, Hussein, Mustafa M, El-Abadelah
Publikováno v:
Zeitschrift für Naturforschung C. 78:133-140
Model α-chloro-β-nitrothieno[2,3-c]pyridazines incorporating N1-(aryl) entity appended with ortho-methoxycarbonyl or trifluoromethyl group were prepared via intramolecular cyclization of their respective N-arylhydrazone precursors. Interaction of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a527440436a0758f39b6e5a764bb3471
https://doi.org/10.1515/znc-2022-0080
https://doi.org/10.1515/znc-2022-0080
Autor:
Mustafa M. El-Abadelah, Ahmad H. Abdullah, Jalal A. Zahra, Salim S. Sabri, Mohammed M. Abadleh, Firas F. Awwadi
Publikováno v:
Letters in Organic Chemistry. 19:504-510
A set of triethylammonium 4-oxo-6-pyridinethiolate–1,3,4-thiadiazoline hybrids (3a-e) were prepared via the reaction of ethyl 2-chloro-6-cyclopropyl-3- nitro-4-oxothieno[2,3-b]pyridine- 5-carboxylate (2) with the appropriate thiobenzoyl- hydrazide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a86caa39d5d65c5a6a5767b1bb1972a6
https://doi.org/10.2174/1570178618666211110141423
https://doi.org/10.2174/1570178618666211110141423
Autor:
Areej M. Jaber, Jalal A. Zahra, Salim S. Sabri, Monther A. Khanfar, Firas F. Awwadi, Mustafa M. El-Abadelah
Publikováno v:
Current Organic Chemistry. 26:542-549
Background: A direct synthesis of functionalized spiro[oxindole-3,3'-pyrrolines] is achieved via thermodynamic control (~60 oC), three-component 1,4-dipolar cycloaddition reaction involving 3-phenylimidazo[5,1-a]isoquinoline, dimethyl acetylenedicarb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6d52db29d0a543d7a95ea313f6d9ba5
https://doi.org/10.2174/1385272826666220221141306
https://doi.org/10.2174/1385272826666220221141306
Autor:
Mustafa M. El-Abadelah, Jalal A. Zahra, Mohammed M. Abadleh, Salim S. Sabri, Firas F. Awwadi, Ahmad Ahmad Abdullah, Qasem Abdallah
Publikováno v:
Current Organic Synthesis. 19:279-290
Introduction: The preparation of model 6-chloro-5-nitrothieno[2,3-c]pyridazines incorporating (2'-halo-5'-nitrophenyl) entity is described. Interaction of these substrates with N'-(aryl)benzothiohydrazides, in the presence of triethylamine, followed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1176c47608587c0242e43a82bc51a62
https://doi.org/10.2174/1570179418666211109112148
https://doi.org/10.2174/1570179418666211109112148