Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Salim Abdool, Karim"'
Autor:
Nicaise Ndembi, Tadesse T. Mekonen, Morenike Oluwatoyin Folayan, Nebiyu Dereje, Adriaan Kruger, Joseph Fokam, Elvis Temfack, Tajudeen Raji, Jean Nachega, Yap Boum, Trevor A. Crowell, Alain Ngashi Ngongo, Souleymane Mboup, Francine Ntoumi, Glaudina Loots, Michael Makanga, Samba Sow, Salim Abdool Karim, John Nkengasong
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-6 (2024)
Enhancing the clinical trial capabilities within Africa is essential to augment the continent’s pandemic prevention, preparedness and response efforts. Here, we describe the critical challenges of clinical trials in Africa and draw upon the lessons
Externí odkaz:
https://doaj.org/article/f901b011571e44ce8aaf29e66b9abf00
Autor:
Natasha Samsunder, Aida Sivro, Razia Hassan-Moosa, Lara Lewis, Zahra Kara, Cheryl Baxter, Quarraisha Abdool Karim, Salim Abdool Karim, Ayesha B. M. Kharsany, Kogieleum Naidoo, Sinaye Ngcapu
Publikováno v:
Diagnostic and Prognostic Research, Vol 8, Iss 1, Pp 1-5 (2024)
Abstract Background and objective Saliva has been proposed as a potential more convenient, cost-effective, and easier sample for diagnosing SARS-CoV-2 infections, but there is limited knowledge of the impact of saliva volumes and stages of infection
Externí odkaz:
https://doaj.org/article/17205c6b0b3e41e38e9d6a534eae2c71
Autor:
Sarah B Joseph, Melissa-Rose Abrahams, Matthew Moeser, Lynn Tyers, Nancie M Archin, Olivia D Council, Amy Sondgeroth, Ean Spielvogel, Ann Emery, Shuntai Zhou, Deelan Doolabh, Sherazaan D Ismail, Salim Abdool Karim, David M Margolis, Sergei Kosakovsky Pond, Nigel Garrett, Ronald Swanstrom, Carolyn Williamson
Publikováno v:
PLoS Pathogens, Vol 20, Iss 2, p e1011974 (2024)
People with HIV-1 (PWH) on antiretroviral therapy (ART) can maintain undetectable virus levels, but a small pool of infected cells persists. This pool is largely comprised of defective proviruses that may produce HIV-1 proteins but are incapable of m
Externí odkaz:
https://doaj.org/article/7fa9d4a490f64aa4ab74aa4822d66bd9
Autor:
Natasha Samsunder, Gila Lustig, Slindile Ngubane, Thando Glory Maseko, Santhuri Rambaran, Sinaye Ngcapu, Stanley Nzuzo Magini, Lara Lewis, Cherie Cawood, Ayesha B. M. Kharsany, Quarraisha Abdool Karim, Salim Abdool Karim, Kogieleum Naidoo, Aida Sivro
Publikováno v:
Diagnostic and Prognostic Research, Vol 7, Iss 1, Pp 1-6 (2023)
Abstract Background Rapid antigen tests detecting SARS-CoV-2 were shown to be a useful tool in managing the COVID-19 pandemic. Here, we report on the results of a prospective diagnostic accuracy study of four SARS-CoV-2 rapid antigen tests in a South
Externí odkaz:
https://doaj.org/article/505b48ee824d48f691d115c05059f399
Autor:
Nigel Garrett, Farzana Osman, Sharana Mahomed, Edmund Capparelli, Nonhlanhla Yende Zuma, Derseree Archary, Penny Moore, Natasha Samsunder, Lynn Morris, Salim Abdool Karim, Catherine Hankins, Carolyn Williamson, Bruno Pozzetto, Kevin Carlton, Richard A Koup, Quarraisha Abdool Karim, Leila Mansoor, Tanuja Narayansamy Gengiah, Ishana Harkoo, Precious Radebe, Izukanji T Sikazwe, Disebo Potloane, Nqobile Myeni, Nicole Doria Rose, Lucio Gama, Sandeep Narpala, Leonid Serebryannyy
Publikováno v:
BMJ Open, Vol 13, Iss 8 (2023)
Introduction Women-controlled HIV prevention technologies that overcome adherence challenges of available daily oral pre-exposure prophylaxis and give women a choice of options are urgently needed. Broadly neutralising monoclonal antibodies (bnAbs) a
Externí odkaz:
https://doaj.org/article/88fe366c8a104a4da061d0ee7548e10d
Autor:
Peter J Hotez, Lois Privor-Dumm, Melanie Saville, Jerome H Kim, Sarah Gilbert, Salim Abdool-Karim, Didi Thompson, Jean-Louis Excler
Publikováno v:
BMJ Global Health, Vol 8, Iss 6 (2023)
The COVID-19 pandemic triggered a sense of vulnerability and urgency that led to concerted actions by governments, funders, regulators and industry to overcome traditional challenges for the development of vaccine candidates and to reach authorisatio
Externí odkaz:
https://doaj.org/article/c60cd7d6c7bb46068a2dfbdc2736279f
Autor:
Peter J Hotez, Lois Privor-Dumm, Melanie Saville, Jerome H Kim, Sarah Gilbert, Salim Abdool-Karim, Didi Thompson, Jean-Louis Excler
Publikováno v:
BMJ Global Health, Vol 8, Iss 6 (2023)
Through the experiences gained by accelerating new vaccines for both Ebola virus infection and COVID-19 in a public health emergency, vaccine development has benefited from a ‘multiple shots on goal’ approach to new vaccine targets. This approach
Externí odkaz:
https://doaj.org/article/92d6ee737c1d4e9cb905d47e32dd3d83
Autor:
Nokukhanya Msomi, Kogieleum Naidoo, Nonhlanhla Yende-Zuma, Nesri Padayatchi, Kerusha Govender, Jerome Amir Singh, Salim Abdool-Karim, Quarraisha Abdool-Karim, Koleka Mlisana
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Hepatitis B virus (HBV), Human Immunodeficiency virus (HIV) and Tuberculosis (TB) are common infections in South Africa. We utilized the opportunity of care provision for HIV-TB co-infected patients to better understand the relati
Externí odkaz:
https://doaj.org/article/a75ea06cc11547e1bd4f21bc2f96172e
Autor:
Cheryl Baxter, Nonhlanhla Yende Zuma, Natasha Samsunder, Salim Abdool Karim, Catherine Hankins, Quarraisha Abdool Karim, Bruno Pozzetto, Leila Mansoor, Tanuja Narayansamy Gengiah, Ishana Harkoo, Precious Radebe, B Maharaj, Marc M Baum, John A Moss
Publikováno v:
BMJ Open, Vol 12, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/27539166663e4cdd94f4ddd64dbb99c3
Autor:
Dieter Mielke, Gama Bandawe, Jie Zheng, Jennifer Jones, Melissa-Rose Abrahams, Valerie Bekker, Christina Ochsenbauer, Nigel Garrett, Salim Abdool Karim, Penny L. Moore, Lynn Morris, David Montefiori, Colin Anthony, Guido Ferrari, Carolyn Williamson
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11 (2021)
Despite antibody-dependent cellular cytotoxicity (ADCC) responses being implicated in protection from HIV-1 infection, there is limited evidence that they control virus replication. The high mutability of HIV-1 enables the virus to rapidly adapt, and
Externí odkaz:
https://doaj.org/article/fd1a9e56d1df41cf85ae7238ccf3f401