Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Salim, Sharopov"'
Publikováno v:
eLife, Vol 6 (2017)
Programmed cell death widely but heterogeneously affects the developing brain, causing the loss of up to 50% of neurons in rodents. However, whether this heterogeneity originates from neuronal identity and/or network-dependent processes is unknown. H
Externí odkaz:
https://doaj.org/article/bc08d7aedd0e4d3484a7178db1e8cddf
Autor:
Paula Winkler, Akihito Okabe, Werner Kilb, Rie Uehara, Aniello Lombardi, Lisa Halbhuber, Salim Sharopov, Heiko J. Luhmann
Publikováno v:
Epilepsy research. 157
In the immature brain the neurotransmitter γ-amino butyric acid (GABA) mediates a membrane depolarization and can contribute to both, inhibition and excitation. Therefore the consequences of a positive modulation of GABA(A) receptors by neurosteroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d75244fda1f81419a077d9c79beb4349
https://pubmed.ncbi.nlm.nih.gov/31499340
https://pubmed.ncbi.nlm.nih.gov/31499340
Gadd45α modulates aversive learning through post‐transcriptional regulation of memory‐related mRNA s
Autor:
Beat Lutz, Christof Niehrs, Heiko J. Luhmann, Emil Karaulanov, Andrea Conrad, Wolfram H. Gruhn, Mathias S. Gierl, Salim Sharopov, Werner Kilb, Andrea I. Schäfer, Alejandro Aparisi Rey, Stephan Guggenhuber, Ruth Jelinek, Luigi Pennella, Khelifa Arab, Christina Maul, Caroline Brandes
Publikováno v:
EMBO Reports
Learning is essential for survival and is controlled by complex molecular mechanisms including regulation of newly synthesized mRNAs that are required to modify synaptic functions. Despite the well‐known role of RNA‐binding proteins (RBPs) in mRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8167d7915e6b644445da309d242c6659
https://doi.org/10.15252/embr.201846022
https://doi.org/10.15252/embr.201846022
Autor:
Klaus Ballanyi, Chase Kantor, Werner Kilb, E. Mildenberger, Araya Ruangkittisakul, Heiko J. Luhmann, Salim Sharopov, Junya Kuribayashi
Publikováno v:
Neuroscience. 301:106-120
Treatment of apnea of prematurity with methylxanthines like caffeine, aminophylline or theophylline can evoke hippocampal seizures. However, it is unknown at which interstitial brain concentrations methylxanthines promote such neonatal seizures or in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c7902b6362d44127ca38eaf44b7367
https://doi.org/10.1016/j.neuroscience.2015.05.069
https://doi.org/10.1016/j.neuroscience.2015.05.069
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
Programmed cell death widely but heterogeneously affects the developing brain, causing the loss of up to 50% of neurons in rodents. However, whether this heterogeneity originates from neuronal identity and/or network-dependent processes is unknown. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61dc4754377e9eb5edbee3631adb4b99
http://europepmc.org/articles/PMC5582867
http://europepmc.org/articles/PMC5582867
Autor:
Sergei Kirischuk, Sergei N. Kolbaev, Salim Sharopov, Werner Kilb, Heiko J. Luhmann, Rongqing Chen, Haiyan Sun
Publikováno v:
Epilepsy Research. 108:182-189
GABA transporters (GATs) are an essential element of the GABAergic system, which regulate excitability in the central nervous system and are thus used as targets for anticonvulsive therapy. However, in the immature nervous system the functions of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af516f673a9e8d8783584c5dbeaeae9c
https://doi.org/10.1016/j.eplepsyres.2013.11.019
https://doi.org/10.1016/j.eplepsyres.2013.11.019
Autor:
Alejandro J. Pernia-Andrade, Ako Kato, Rita Nyilas, István Katona, Salim Sharopov, Hanns Ulrich Zeilhofer, Carolin von Schoultz, Pradeep Punnakkal
Publikováno v:
The Journal of Physiology. 590:4717-4733
Key points • Synaptic plasticity between primary nociceptors and second order dorsal horn neurons serves key roles in pain and analgesia • A contribution of NMDA receptors to long-term potentiation and long-term depression at these synapses has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8613f081bcbfb02acdd69d3960edaec7
https://doi.org/10.1113/jphysiol.2012.234229
https://doi.org/10.1113/jphysiol.2012.234229
Autor:
Viviane Bernedo, Sergey N. Kolbaev, Konrad J. Werhahn, Werner Kilb, Jochen Moser, Salim Sharopov, Heiko J. Luhmann, Rongqing Chen
Publikováno v:
Journal of Neuroscience Research. 90:2020-2033
To investigate whether epileptiform activity in the immature brain is modulated by dopamine, we examined the effects of dopaminergic agonists and antagonists in an intact in vitro preparation of the isolated corticohippocampal formation of immature (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4afb18d1965600a17d8865f0698681b
https://doi.org/10.1002/jnr.23084
https://doi.org/10.1002/jnr.23084
Publikováno v:
Epilepsia. 53:888-896
Summary Purpose: Despite the consistent observation that γ-aminobutyric acid A (GABAA) receptors mediate excitatory responses at perinatal stages, the role of the GABAergic system in the generation of neonatal epileptiform activity remains controver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12393b45751e10a92a0a8a5773b98794
https://doi.org/10.1111/j.1528-1167.2012.03442.x
https://doi.org/10.1111/j.1528-1167.2012.03442.x