Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Salim, Ansari"'
Autor:
Sabrina Lehmann, Bibi Atika, Daniela Grossmann, Christian Schmitt-Engel, Nadi Strohlein, Upalparna Majumdar, Tobias Richter, Matthias Weißkopf, Salim Ansari, Matthias Teuscher, Muhammad Salim Hakeemi, Jianwei Li, Bernhard Weißbecker, Martin Klingler, Gregor Bucher, Ernst A. Wimmer
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Functional genomics uses unbiased systematic genome-wide gene disruption or analyzes natural variations such as gene expression profiles of different tissues from multicellular organisms to link gene functions to particular phenot
Externí odkaz:
https://doaj.org/article/88d6064f752a45169acda44d9d050845
Autor:
Muhammad Salim Hakeemi, Salim Ansari, Matthias Teuscher, Matthias Weißkopf, Daniela Großmann, Tobias Kessel, Jürgen Dönitz, Janna Siemanowski, Xuebin Wan, Dorothea Schultheis, Manfred Frasch, Siegfried Roth, Michael Schoppmeier, Martin Klingler, Gregor Bucher
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background Most of the known genes required for developmental processes have been identified by genetic screens in a few well-studied model organisms, which have been considered representative of related species, and informative—to some de
Externí odkaz:
https://doaj.org/article/f958f28f3e5f489d8ea8a8d99b722eb3
Autor:
Dorothea Schultheis, Matthias Weißkopf, Christoph Schaub, Salim Ansari, Van Anh Dao, Daniela Grossmann, Upalparna Majumdar, Muhammad Salim Hakeemi, Nicole Troelenberg, Tobias Richter, Christian Schmitt-Engel, Jonas Schwirz, Nadi Ströhlein, Matthias Teuscher, Gregor Bucher, Manfred Frasch
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 4, Pp 1009-1026 (2019)
Although muscle development has been widely studied in Drosophila melanogaster there are still many gaps in our knowledge, and it is not known to which extent this knowledge can be transferred to other insects. To help in closing these gaps we partic
Externí odkaz:
https://doaj.org/article/9f7f4913a9bf4d50a1f1e58f788f25e0
Autor:
David A. Doetsch, Salim Ansari, Ole Jensen, Lukas Gebauer, Christof Dücker, Jürgen Brockmöller, Alexandra Sachkova
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8430 (2022)
Many organic cations (OCs) may be transported through membranes by a genetically still uncharacterized proton-organic cation (H + OC) antiporter. Here, we characterized an extended substrate spectrum of this antiporter. We studied the uptake of 72 dr
Externí odkaz:
https://doaj.org/article/44d03a538c3348d984624174864b051f
College students' diverse outcomes are said to be influenced by their motivation for their studies. Academic motivation is the desire or interest students have in participating in their education and college experience. Research has repeatedly shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a77d11972574dbb5a168f13d41d65f
Autor:
Sabrina, Lehmann, Bibi, Atika, Daniela, Grossmann, Christian, Schmitt-Engel, Nadi, Strohlein, Upalparna, Majumdar, Tobias, Richter, Matthias, Weißkopf, Salim, Ansari, Matthias, Teuscher, Muhammad Salim, Hakeemi, Jianwei, Li, Bernhard, Weißbecker, Martin, Klingler, Gregor, Bucher, Ernst A, Wimmer
Background Functional genomics uses unbiased systematic genome-wide gene disruption or analyzes natural variations such as gene expression profiles of different tissues from multicellular organisms to link gene functions to particular phenotypes. Fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf42b01b633517770e017d0513f7a697
https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/21416
https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/21416
Publikováno v:
Pharmacology & Therapeutics. 239:108283
About 30% of all small molecular drugs are organic cations (OCs). If these are more or less hydrophilic, they require membrane transporters to pass through biological membranes. Here, the proton-organic cation (Hsup+/supOC) antiporter may play a phys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27fb86db1de252ae98cdc391b42833c
https://doi.org/10.1016/j.pharmthera.2022.108283
https://doi.org/10.1016/j.pharmthera.2022.108283
Publikováno v:
Biochemical pharmacology. 192
Background Although psychostimulants apparently do cross the BBB, it is poorly understood how these hydrophilic and positively charged molecules can pass the blood-brain barrier (BBB). That may be mediated by a genetically still uncharacterized H+/OC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4323df6b3226ae1053352700788bb317
https://pubmed.ncbi.nlm.nih.gov/34464621
https://pubmed.ncbi.nlm.nih.gov/34464621
Autor:
Muhammad Salim Hakeemi, Salim Ansari, Matthias Teuscher, Matthias Weißkopf, Daniela Großmann, Tobias Kessel, Jürgen Dönitz, Janna Siemanowski, Xuebin Wan, Dorothea Schultheis, Manfred Frasch, Siegfried Roth, Michael Schoppmeier, Martin Klingler, Gregor Bucher
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-13 (2022)
Background Most of the known genes required for developmental processes have been identified by genetic screens in a few well-studied model organisms, which have been considered representative of related species, and informative—to some degree—fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f6a139c6c802abe1f1ce1457b343e0
https://pubmed.ncbi.nlm.nih.gov/35135533
https://pubmed.ncbi.nlm.nih.gov/35135533
Autor:
Muhammad Salim Hakeemi, Matthias Teuscher, Janna Siemanowski, Dorothea Schultheis, Siegfried Roth, Michael Schoppmeier, Manfred Frasch, Gregor Bucher, Salim Ansari, Wan X, Jürgen Dönitz, Kessel T, Martin Klingler, Großmann D, Matthias Weißkopf
Most gene functions were detected by screens in very few model organisms but it has remained unclear how comprehensive these data are. Here, we expanded our RNAi screen in the red flour beetleTribolium castaneumto cover more than half of the protein-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::959fd027d05a36f03c7be86bcc6531b8
https://doi.org/10.1101/2021.02.03.429118
https://doi.org/10.1101/2021.02.03.429118