Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Salim, Abdisalaam"'
Autor:
Salim Abdisalaam, Shibani Mukherjee, Souparno Bhattacharya, Sharda Kumari, Debapriya Sinha, Janice Ortega, Guo-Min Li, Hesham A Sadek, Sunil Krishnan, Aroumougame Asaithamby
Publikováno v:
Nucleic Acids Research. 50:2681-2699
Cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS) is activated in cells with defective DNA damage repair and signaling (DDR) factors, but a direct role for DDR factors in regulating cGAS activation in response to micronuclear D
Autor:
Sharda Kumari, Shibani Mukherjee, Debapriya Sinha, Salim Abdisalaam, Sunil Krishnan, Aroumougame Asaithamby
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8151 (2020)
Radiation therapy (RT), an integral component of curative treatment for many malignancies, can be administered via an increasing array of techniques. In this review, we summarize the properties and application of different types of RT, specifically,
Externí odkaz:
https://doaj.org/article/e92d53d4b40d40c9ae7cea100d9c96bc
Autor:
Shibani Mukherjee, Debapriya Sinha, Souparno Bhattacharya, Kalayarasan Srinivasan, Salim Abdisalaam, Aroumougame Asaithamby
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3442 (2018)
Werner Syndrome (WS) is an autosomal recessive disorder characterized by the premature development of aging features. Individuals with WS also have a greater predisposition to rare cancers that are mesenchymal in origin. Werner Syndrome Protein (WRN)
Externí odkaz:
https://doaj.org/article/dfc64d4e172a4cc9984e59075c53ef54
Autor:
Souparno Bhattacharya, Jerry W. Shay, Aroumougame Asaithamby, Esra A. Akbay, Shibani Mukherjee, Hesham A. Sadek, Debapriya Sinha, Mingrui Zhu, Kalayarasan Srinivasan, Salim Abdisalaam
Publikováno v:
J Biol Chem
Defective DNA damage response (DDR) signaling is a common mechanism that initiates and maintains the cellular senescence phenotype. Dysfunctional telomeres activate DDR signaling, genomic instability, and cellular senescence, but the links among thes
Autor:
Chukwuemeka George Anene-Nzelu, Michael Kinter, Hesham A. Sadek, Jainy J. Savla, Salim Abdisalaam, Luke I. Szweda, Abdallah Elnwasany, Roger Foo, Ursa Bezan Petric, Ana Helena Macedo Pereira, Ivan Menendez-Montes, Mohammed Kanchwala, Chalermchai Khemtong, Yuji Nakada, Wilson Lek Wen Tan, Shujuan Li, Craig R. Malloy, Mahmoud S. Ahmed, Kaitlyn M. Eckert, Ngoc Uyen Nhi Nguyen, A. Dean Sherry, Emily L Ensley, Aroumougame Asaithamby, Gaurav Sharma, Gonçalo Vale, Chao Xing, Linzhang Huang, Matthew A. Mitsche, Nicholas T. Lam, Philip W. Shaul, Alisson C. Cardoso, Joseph A. Hill, Waleed M. Elhelaly, Jeffrey G. McDonald
Publikováno v:
Nature Metabolism. 2:167-178
The neonatal mammalian heart is capable of regeneration for a brief window of time after birth. However, this regenerative capacity is lost within the first week of life, which coincides with a postnatal shift from anaerobic glycolysis to mitochondri
Autor:
Nicholas T. Lam, Hesham A. Sadek, Salim Abdisalaam, Shibani Mukherjee, Aroumougame Asaithamby, Ivan Menendez-Montes, Feng Xiao, Luke I. Szweda
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
The inability of adult mammalian cardiomyocytes to proliferate underpins the development of heart failure following myocardial injury. Although the newborn mammalian heart can spontaneously regenerate for a short period of time after birth, this abil
Autor:
Janice Ortega Rodriguez, Souparno Bhattacharya, Asaithamby Aroumougame, Guo-Min Li, Hesham A. Sadek, Salim Abdisalaam, Shibani Mukherjee, Debapriya Sinha, Sharda Kumari
Cyclic GMP-AMP synthase (cGAS), an important component of immune signaling, is hyperactivated in cells defective for DNA damage response (DDR) signaling. However, a direct role for DDR factors in the regulation of cGAS functions is mostly unknown. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b24aba9650f36fe17cef10e6a085c64
https://doi.org/10.1101/2020.07.27.222380
https://doi.org/10.1101/2020.07.27.222380
Autor:
Alisson C, Cardoso, Nicholas T, Lam, Jainy J, Savla, Yuji, Nakada, Ana Helena M, Pereira, Abdallah, Elnwasany, Ivan, Menendez-Montes, Emily L, Ensley, Ursa Bezan, Petric, Gaurav, Sharma, A Dean, Sherry, Craig R, Malloy, Chalermchai, Khemtong, Michael T, Kinter, Wilson Lek Wen, Tan, Chukwuemeka George, Anene-Nzelu, Roger Sik-Yin, Foo, Ngoc Uyen Nhi, Nguyen, Shujuan, Li, Mahmoud Salama, Ahmed, Waleed M, Elhelaly, Salim, Abdisalaam, Aroumougame, Asaithamby, Chao, Xing, Mohammed, Kanchwala, Goncalo, Vale, Kaitlyn M, Eckert, Matthew A, Mitsche, Jeffrey G, McDonald, Joseph A, Hill, Linzhang, Huang, Philip W, Shaul, Luke I, Szweda, Hesham A, Sadek
Publikováno v:
Nature metabolism
The neonatal mammalian heart is capable of regeneration for a brief window of time after birth. However, this regenerative capacity is lost within the first week of life, which coincides with a postnatal shift from anaerobic glycolysis to mitochondri
Autor:
Zeping Hu, James E. Faber, Joseph A. Hill, Hua Zhang, Gabriele G. Schiattarella, Ajay M. Shah, Salim Abdisalaam, Suwannee Thet, Zhigang Lu, Chao Xing, Michael Kinter, Hesham A. Sadek, Diana C. Canseco, Ralph J. DeBerardinis, Luke I. Szweda, Cheng Cheng Zhang, Orhan K. Öz, Wataru Kimura, Celio X.C. Santos, Aroumougame Asaithamby, Yuji Nakada
Publikováno v:
Nature. 541:222-227
The adult mammalian heart is incapable of regeneration following cardiomyocyte loss, which underpins the lasting and severe effects of cardiomyopathy. Recently, it has become clear that the mammalian heart is not a post-mitotic organ. For example, th
Autor:
Debapriya Sinha, Souparno Bhattacharya, Aroumougame Asaithamby, Shibani Mukherjee, Kalayarasan Srinivasan, Salim Abdisalaam
Previously, DNA damage sensing, repairing and signaling machineries were thought to mainly suppress genomic instability in response to genotoxic stress. Emerging evidence indicates a crosstalk between DNA repair machinery and the immune system. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d35af74edc50c2d9dafeb06c725b303
https://doi.org/10.1016/bs.apcsb.2018.11.004
https://doi.org/10.1016/bs.apcsb.2018.11.004