Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Salil Srivastava"'
Autor:
Gabriela Warpsinski, Matthew J. Smith, Salil Srivastava, Thomas P. Keeley, Richard C.M. Siow, Paul A. Fraser, Giovanni E. Mann
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101708- (2020)
Ischemic stroke is associated with a surge in reactive oxygen species generation during reperfusion. The narrow therapeutic window for the delivery of intravenous thrombolysis and endovascular thrombectomy limits therapeutic options for patients. Thu
Externí odkaz:
https://doaj.org/article/047eb14f816f4bad9543c59bb2faf295
Autor:
Salil Srivastava, Philip J. Blower, Aisah A. Aubdool, Robert C. Hider, Giovanni E. Mann, Richard C. Siow
Publikováno v:
Scientific Reports, Vol 6, Iss 1, Pp 1-13 (2016)
Abstract Cu(II)ATSM was developed as a hypoxia sensitive positron emission tomography agent. Recent reports have highlighted the neuroprotective properties of Cu(II)ATSM, yet there are no reports that it confers cardioprotection. We demonstrate that
Externí odkaz:
https://doaj.org/article/539979e057014d39ad5ec5aeb895f034
Publikováno v:
Journal of Oral Biology and Craniofacial Research, Vol 4, Iss 2, Pp 114-119 (2014)
Problem considered: The objective was to evaluate and compare the clinical and radiographic efficacy of two different combinations of antibacterial drugs when used in non-instrumental endodontic treatment of necrosed primary teeth. Materials and meth
Externí odkaz:
https://doaj.org/article/780ad95888d94a01b6eacfd7a5ac1a71
Publikováno v:
Scholars Journal of Applied Medical Sciences. 8:1823-1827
Autor:
Giovanni E. Mann, Richard C.M. Siow, Matthew J. Smith, Paul A. Fraser, Salil Srivastava, Thomas P. Keeley, Gabriela Warpsinski
Publikováno v:
Redox Biology, Vol 37, Iss, Pp 101708-(2020)
Redox Biology
Redox Biology
Ischemic stroke is associated with a surge in reactive oxygen species generation during reperfusion. The narrow therapeutic window for the delivery of intravenous thrombolysis and endovascular thrombectomy limits therapeutic options for patients. Thu
Autor:
R Choo-Wing, O Bonneau, K Choy, D Rowlands, Salil Srivastava, A Martinez Ledo, M Morris, K Subramanian, T Shavlakadze
Publikováno v:
03.02 - Airway cell biology and immunopathology.
Mitochondrial dysfunction contributes to the pathogenesis of lung aging and chronic obstructive pulmonary disease (COPD), however the underlying mechanisms remain poorly understood. In a rat model of lung aging, RNA sequencing of lung tissue revealed
Publikováno v:
Poster abstracts.
Introduction Ischaemic stroke is a major contributor to adult disability in developed countries. However, the only clinically approved acute treatment is delivery of the thrombolytic agent, alteplase, that has a narrow window of 6 hour post-stroke. T
Autor:
Diana Cash, Paul A. Fraser, Michel Modo, Michael R. Duchen, Giovanni E. Mann, Alessio Alfieri, Richard C.M. Siow, Steven Williams, Salil Srivastava
Publikováno v:
Free Radical Biology and Medicine. 65:1012-1022
Disruption of the blood-brain barrier (BBB) and cerebral edema are the major pathogenic mechanisms leading to neurological dysfunction and death after ischemic stroke. The brain protects itself against infarction via activation of endogenous antioxid
Publikováno v:
The Journal of Physiology. 591:3525-3538
Activation of the redox-sensitive transcription factor NF-E2 related factor 2 (Nrf2) affords protection against cerebral ischaemia-reperfusion injury via the upregulation of antioxidant defence genes. We have quantified for the first time Nrf2 conten
Autor:
Giuseppe, Maltese, Paraskevi-Maria, Psefteli, Benedetta, Rizzo, Salil, Srivastava, Luigi, Gnudi, Giovanni E, Mann, Richard C M, Siow
Publikováno v:
Journal of Cellular and Molecular Medicine
Vascular ageing in conditions such as atherosclerosis, diabetes and chronic kidney disease, is associated with the activation of the renin angiotensin system (RAS) and diminished expression of antioxidant defences mediated by the transcription factor