Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Salih Sanlioglu"'
Autor:
Yunus Emre, Eksi, Atil, Bisgin, Ahter D, Sanlioglu, Reha Onur, Azizoglu, Mustafa Kemal, Balci, Thomas S, Griffith, Salih, Sanlioglu
Publikováno v:
Advances in experimental medicine and biology.
Since insulin deficiency results from pancreatic beta-cell destruction, all type 1 and most type 2 diabetes patients eventually require life-long insulin injections. Insulin gene synthesis could also be impaired due to insulin gene mutations as obser
Publikováno v:
Human Gene Therapy. 32:541-562
Severe acute respiratory syndrome (SARS) is a newly emerging infectious disease (COVID-19) caused by the novel coronavirus SARS-coronavirus 2 (CoV-2). To combat the devastating spread of SARS-CoV-2, extraordinary efforts from numerous laboratories ha
Autor:
Yunus Emre Eksi, Atil Bisgin, Ahter D. Sanlioglu, Reha Onur Azizoglu, Mustafa Kemal Balci, Thomas S. Griffith, Salih Sanlioglu
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783031284236
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08d92c7eecd7e8374cb857af6181b0e3
https://doi.org/10.1007/5584_2022_746
https://doi.org/10.1007/5584_2022_746
Autor:
Irem Hicran Ozbudak, Salih Sanlioglu, Cigdem Aydin, Elif Pestereli, Gulgun Erdogan, Ahter Dilsad Sanlioglu, Atil Bisgin, Tayup Simsek
Publikováno v:
Eastern Journal Of Medicine. 24:361-370
Endometrial cancer is the sixth most common neoplasm in women worldwide, with a rising incidence largely attributed to the ongoing obesity epidemic. TNF-Related Apoptosis-Inducing Ligand (TRAIL) and TRAIL receptors have been tested for their predicti
Publikováno v:
World Journal of Stem Cells
Targeted genome editing is a continually evolving technology employing programmable nucleases to specifically change, insert, or remove a genomic sequence of interest. These advanced molecular tools include meganucleases, zinc finger nucleases, trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69e541e45fd8431d81c5ca2ad429914
https://aperta.ulakbim.gov.tr/record/233134
https://aperta.ulakbim.gov.tr/record/233134
Autor:
Fulya Erendor, Ahter Dilsad Sanlioglu, Elif Ozgecan Sahin, Mustafa Kemal Balci, Thomas S. Griffith, Salih Sanlioglu
Publikováno v:
Gene therapy. 28(3-4)
Type 1 diabetes (T1DM) is an autoimmune condition in which the immune system attacks and destroys insulin-producing beta cells in the pancreas leading to hyperglycemia. Vasoactive intestinal peptide (VIP) manifests insulinotropic and anti-inflammator
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1879
Lentiviral vectors (LVs) have been increasingly used in clinical gene therapy applications particularly due to their efficient gene transfer ability, lack of interference from preexisting viral immunity, and long-term gene expression they provide. Pu
Generation of a Novel Gene Therapy Vector Encoding Beta-Cell–Specific Insulin for Diabetes Treatment
Publikováno v:
Diabetes. 67
Insulin injection is the main treatment modality especially for patients with type 1 diabetes. Despite the development of several insulin analogs, recent meta-analysis indicated that rapid and long acting insulin analogs provide little benefit compar
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1879
Lentiviral vectors are becoming preferred vectors of choice for clinical gene therapy trials due to their safety, efficacy, and the long-term gene expression they provide. Although the efficacy of lentiviral vectors is mainly predetermined by the the
Publikováno v:
Human gene therapy. 29(7)
Postprandial glucose-induced insulin secretion from the islets of Langerhans is facilitated by glucagon-like peptide-1 (GLP-1)-a metabolic hormone with insulinotropic properties. Among the variety of effects it mediates, GLP-1 induces delta cell secr