Výsledky vyhledávání - "Salentijn Elma"

Akademický článek

Expansion of the gamma-gliadin gene family in Aegilops and Triticum

Autor: Goryunova Svetlana V, Salentijn Elma MJ, Chikida Nadejda N, Kochieva Elena Z, van der Meer Ingrid M, Gilissen Luud JWJ, Smulders Marinus JM

Publikováno v: BMC Evolutionary Biology, Vol 12, Iss 1, p 215 (2012)

Abstract Background The gamma-gliadins are considered to be the oldest of the gliadin family of storage proteins in Aegilops/Triticum. However, the expansion of this multigene family has not been studied in an evolutionary perspective. Results We hav

Externí odkaz: https://doaj.org/article/ab4838d90b0047cea8a6412d65040b4b

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Akademický článek

Celiac disease T-cell epitopes from gamma-gliadins: immunoreactivity depends on the genome of origin, transcript frequency, and flanking protein variation

Autor: Salentijn Elma MJ, Mitea D, Goryunova Svetlana V, van der Meer Ingrid M, Padioleau Ismael, Gilissen Luud JWJ, Koning Frits, Smulders Marinus JM

Publikováno v: BMC Genomics, Vol 13, Iss 1, p 277 (2012)

Abstract Background Celiac disease (CD) is caused by an uncontrolled immune response to gluten, a heterogeneous mixture of wheat storage proteins. The CD-toxicity of these proteins and their derived peptides is depending on the presence of specific T

Externí odkaz: https://doaj.org/article/1c7ef484b2b74b9d87dcc960ac63e3cd

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Akademický článek

Removing celiac disease-related gluten proteins from bread wheat while retaining technological properties: a study with Chinese Spring deletion lines

Autor: Bosch Dirk, Dekking Liesbeth, Salentijn Elma MJ, Schuit Cees, van Herpen Teun WJM, van den Broeck Hetty C, Hamer Rob J, Smulders Marinus JM, Gilissen Ludovicus JWJ, van der Meer Ingrid M

Publikováno v: BMC Plant Biology, Vol 9, Iss 1, p 41 (2009)

Abstract Background Gluten proteins can induce celiac disease (CD) in genetically susceptible individuals. In CD patients gluten-derived peptides are presented to the immune system, which leads to a CD4+ T-cell mediated immune response and inflammati

Externí odkaz: https://doaj.org/article/4b50408d7cb4447eb7906c1c1778a272

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Akademický článek

Tetraploid and hexaploid wheat varieties reveal large differences in expression of alpha-gliadins from homoeologous Gli-2 loci

Autor: Bastien Thomas, van den Broeck Hetty C, van der Meer Ingrid M, Bas Noor, Goryunova Svetlana V, Salentijn Elma MJ, Gilissen Luud JWJ, Smulders Marinus JM

Publikováno v: BMC Genomics, Vol 10, Iss 1, p 48 (2009)

Abstract Background Α-gliadins form a multigene protein family encoded by multiple α-gliadin (Gli-2) genes at three genomic loci, Gli-A2, Gli-B2 and Gli-D2, respectively located on the homoeologous wheat chromosomes 6AS, 6BS, and 6DS. These protein

Externí odkaz: https://doaj.org/article/c1d03ecf88f34536be4435675308f1fe

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Akademický článek

Alpha-gliadin genes from the A, B, and D genomes of wheat contain different sets of celiac disease epitopes

Autor: van Veelen Peter A, Schenk Martijn F, Vorst Oscar, Salentijn Elma, Mitreva Makedonka, van der Schoot Johanna, Goryunova Svetlana V, van Herpen Teun WJM, Koning Frits, van Soest Loek JM, Vosman Ben, Bosch Dirk, Hamer Rob J, Gilissen Luud JWJ, Smulders Marinus JM

Publikováno v: BMC Genomics, Vol 7, Iss 1, p 1 (2006)

Abstract Background Bread wheat (Triticum aestivum) is an important staple food. However, wheat gluten proteins cause celiac disease (CD) in 0.5 to 1% of the general population. Among these proteins, the α-gliadins contain several peptides that are

Externí odkaz: https://doaj.org/article/9ea1f2a53e544adfb3ebce9467957b37

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