Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Salem Chouchane"'
Publikováno v:
Protein Science. 11:58-64
A single amino acid mutation (W321F) in Mycobacterium tuberculosis catalase-peroxidase (KatG) was constructed by site-directed mutagenesis. The purified mutant enzyme was characterized using optical and electron paramagnetic resonance spectroscopy, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8b66d9019179fbbfafa1fe44b855d3
https://doi.org/10.1110/ps.09902
https://doi.org/10.1110/ps.09902
Autor:
Franz J. Tewes, Boris P. Müller, Joerg Diekmann, Arno Wittig, Detlef J. Veltel, Jan B. Wooten, Salem Chouchane
Publikováno v:
Chemical Research in Toxicology. 19:1602-1610
Free radicals in cigarette smoke have attracted a great deal of attention because they are hypothesized to be responsible in part for several of the pathologies related to smoking. Hydroquinone, catechol, and their methyl-substituted derivatives are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0ad6461831657704115cb54ac9d2b5
https://doi.org/10.1021/tx060162u
https://doi.org/10.1021/tx060162u
Autor:
Xiangbo Zhao, Salem Chouchane, Shengwei Yu, Richard S. Magliozzo, Johannes P. M. Schelvis, Sofia M. Kapetanaki
Publikováno v:
Biochemistry. 44:243-252
Mycobacterium tuberculosis (Mtb) KatG is a catalase-peroxidase that is thought to activate the antituberculosis drug isoniazid (INH). The local environment of Mtb KatG and its most prevalent INH-resistant mutant, KatG(S315T), is investigated with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f359754af188a8276017f36e4bd90d4
https://doi.org/10.1021/bi048097f
https://doi.org/10.1021/bi048097f
Autor:
Shengwei Yu, Johannes P. M. Schelvis, Richard S. Magliozzo, Sofia M. Kapetanaki, Salem Chouchane, Stefania Girotto
Publikováno v:
Biochemistry. 42:3835-3845
KatG from Mycobacterium tuberculosis is a heme-containing catalase-peroxidase, which belongs to the class I peroxidases and is important for activation of the prodrug isoniazid (INH), a front-line antituberculosis drug. In many clinical isolates, res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815ab314b1695b45262e7ed80488ce62
https://doi.org/10.1021/bi026992y
https://doi.org/10.1021/bi026992y
Publikováno v:
Analytical Chemistry. 74:163-170
Stable films of dimyristoylphosphatidylcholine and M. tuberculosis catalase-peroxidase (KatG), several peroxidases, myoglobin, and catalase showed reversible FeIII/FeII voltammetry on pyrolytic graphite electrodes and catalytic current for hydrogen p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c354f8dd98f78d846570c483d41d1e
https://doi.org/10.1021/ac010701u
https://doi.org/10.1021/ac010701u
Publikováno v:
Toxicological & Environmental Chemistry. 75:43-57
Exposure to iron oxides dusts may lead to lung cancers among exposed population. To evaluate the involvement of iron‐containing particles in lipid peroxidation by production of reactive oxygen species, hematite, magnetite (iron oxides), and crocido
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::347c3cc57494cbd22c02064e82857e39
https://doi.org/10.1080/02772240009358891
https://doi.org/10.1080/02772240009358891
Publikováno v:
Cigarette Smoke and Oxidative Stress ISBN: 9783540314103
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb29c2d23aae104357a6ccb0bb6888f7
https://doi.org/10.1007/3-540-32232-9_2
https://doi.org/10.1007/3-540-32232-9_2
Autor:
Richard S. Magliozzo, Sofia M. Kapetanaki, Johannes P. M. Schelvis, Salem Chouchane, Shengwei Yu
Publikováno v:
Journal of inorganic biochemistry. 99(6)
The reaction of Mycobacterium tuberculosis KatG and the mutant KatG(S315T) with two different organic peroxides is studied using resonance Raman spectroscopy. For the first time, an intermediate is observed in a catalase-peroxidase with vibrations th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d46856e318a28b642a608e0919c43bc
https://pubmed.ncbi.nlm.nih.gov/15917090
https://pubmed.ncbi.nlm.nih.gov/15917090
Autor:
Salem Chouchane, Stefania Girotto, Richard S. Magliozzo, Shengwei Yu, Sofia M. Kapetanaki, Johannes P. M. Schelvis
Publikováno v:
The Journal of biological chemistry. 278(10)
Mycobacterium tuberculosiscatalase-peroxidase (KatG) is a heme enzyme considered important for virulence, which is also responsible for activation of the anti-tuberculosis pro-drug isoniazid. Here, we present an analysis of heterogeneity in KatG heme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa2667124b9e80e643d736090607a72
https://pubmed.ncbi.nlm.nih.gov/12506108
https://pubmed.ncbi.nlm.nih.gov/12506108
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 70(2)
Inorganic arsenic (iAs), a known human carcinogen, acts as a tumor promoter in part by inducing a rapid burst of reactive oxygen species (ROS) in mammalian cells. This causes oxidative stress and a subsequent increase in the level of cellular glutath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6253a2a7351126d0559f27c6bfe729f
https://pubmed.ncbi.nlm.nih.gov/12441363
https://pubmed.ncbi.nlm.nih.gov/12441363