Genome-wide association study identifies nox3 as a critical gene for susceptibility to noise-induced hearing loss

Autor: Lavinsky, Joel, Crow, Amanda L, Pan, Calvin, Wang, Juemei, Aaron, Ksenia A, Ho, Maria K, Li, Qingzhong, Salehide, Pehzman, Myint, Anthony, Monges-Hernadez, Maya, Eskin, Eleazar, Allayee, Hooman, Lusis, Aldons J, Friedman, Rick A

Publikováno v: PLoS genetics, vol 11, iss 4

In the United States, roughly 10% of the population is exposed daily to hazardous levels of noise in the workplace. Twin studies estimate heritability for noise-induced hearing loss (NIHL) of approximately 36%, and strain specific variation in sensit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::8bc4157ffb8aa5778ef3dd6f4654d01e
https://escholarship.org/uc/item/6759h8h0

Genome-wide association study identifies nox3 as a critical gene for susceptibility to noise-induced hearing loss.

Autor: Lavinsky J; Graduate Program in Surgical Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America., Crow AL; Department of Preventive Medicine and Institute for Genetic Medicine, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America., Pan C; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California, United States of America., Wang J; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America., Aaron KA; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America., Ho MK; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America., Li Q; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America., Salehide P; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America., Myint A; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America., Monges-Hernadez M; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America., Eskin E; Department of Computer Science, University of California, Los Angeles, Los Angeles, California, United States of America., Allayee H; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California, United States of America., Lusis AJ; Department of Preventive Medicine and Institute for Genetic Medicine, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States of America., Friedman RA; Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.

Publikováno v: PLoS genetics [PLoS Genet] 2015 Apr 16; Vol. 11 (4), pp. e1005094. Date of Electronic Publication: 2015 Apr 16 (Print Publication: 2015).