Synthesis and Inhibitory Effect of Some Indole‐Pyrimidine Based Hybrid Heterocycles on α‐Glucosidase and α‐Amylase as Potential Hypoglycemic Agents

Autor: Prof. Dr. Farid A. Badria, Saleh Atef, Prof. Dr. Abdullah Mohammed Al‐Majid, M. Ali, Dr. Yaseen A. M. M. Elshaier, Dr. Hazem A. Ghabbour, Mohammad Shahidul Islam, Dr. Assem Barakat

Publikováno v: ChemistryOpen, Vol 8, Iss 10, Pp 1288-1297 (2019)

Abstract The Michael addition reaction of barbituric acid with chalcones incorporating the indole scaffold was achieved by using a highly efficient bimetallic Iron–palladium catalyst in the presence of acetylacetone (acac). This catalytic approach

Externí odkaz: https://doaj.org/article/4f67e17a3df0406eafb6b6b9b269de25

Synthesis of Pyridine-Dicarboxamide-Cyclohexanone Derivatives: Anticancer and α-Glucosidase Inhibitory Activities and In Silico Study

Autor: Abdullah Mohammed Al-Majid, Mohammad Shahidul Islam, Saleh Atef, Fardous F. El-Senduny, Farid A. Badria, Yaseen A. M. M. Elshaier, M. Ali, Assem Barakat, A. F. M. Motiur Rahman

Publikováno v: Molecules, Vol 24, Iss 7, p 1332 (2019)

An efficient and practical method for the synthesis of 2,6-diaryl-4-oxo-N,N′-di(pyridin-2-yl)cyclohexane-1,1-dicarboxamide is described in this present study, which occurs through a double Michael addition reaction between diamide and various diben

Externí odkaz: https://doaj.org/article/bf4d86985a7d4562b735350dc9839f26

The restoration and erection of the world's first elevated obelisk.

Autor: Saleh, Atef M.¹ (AUTHOR), Mourad, Sherif A.² (AUTHOR) smourad@eng.cu.edu.eg, Elanwar, Hazem H.² (AUTHOR), Metwally, Omar K.² (AUTHOR), Zeidan, Eissa³ (AUTHOR), Adam, Mahmoud A.^2,4 (AUTHOR), Ameen, Mostafa F.² (AUTHOR), Helal, Khalid R.² (AUTHOR), Sholqamy, Mohamed S.² (AUTHOR), Allam, Hussien E.² (AUTHOR), Ismael, Mohamed A.² (AUTHOR), Mostafa, Khaled A.² (AUTHOR), Helal, Hany M.² (AUTHOR), Elbanhawy, Amr Y.⁵ (AUTHOR), Grosse, Christian U.⁶ (AUTHOR), Bakhoum, Mourad M.^2,6 (AUTHOR), Farag, Mousa M.^2,7 (AUTHOR), Matar, Hani B.⁷ (AUTHOR), Eltobgy, Hanan H.^7,8 (AUTHOR), Moharram, Moustafa I.^2,7 (AUTHOR)

Publikováno v: Scientific Reports. 2/4/2023, Vol. 13 Issue 1, p1-19. 19p.

Synthesis and Inhibitory Effect of Some Indole‐Pyrimidine Based Hybrid Heterocycles on α‐Glucosidase and α‐Amylase as Potential Hypoglycemic Agents

Autor: Assem Barakat, Saleh Atef, Abdullah Mohammed Al-Majid, Hazem A. Ghabbour, M. Ali, Mohammad Shahidul Islam, Yaseen A.M.M. Elshaier, Farid A. Badria

Publikováno v: ChemistryOpen
ChemistryOpen, Vol 8, Iss 10, Pp 1288-1297 (2019)

The Michael addition reaction of barbituric acid with chalcones incorporating the indole scaffold was achieved by using a highly efficient bimetallic Iron–palladium catalyst in the presence of acetylacetone (acac). This catalytic approach produced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8795b44cf0f58a3bb6e72b5dc9ca3d37
http://europepmc.org/articles/PMC6804419

Synthesis of Pyridine-Dicarboxamide-Cyclohexanone Derivatives: Anticancer and α-Glucosidase Inhibitory Activities and In Silico Study

Autor: Mohammad Shahidul Islam, Assem Barakat, Saleh Atef, Fardous F. El-Senduny, Yaseen A.M.M. Elshaier, M. Ali, Farid A. Badria, A. F. M. Motiur Rahman, Abdullah Mohammed Al-Majid

Publikováno v: Molecules, Vol 24, Iss 7, p 1332 (2019)
Molecules
Volume 24
Issue 7

An efficient and practical method for the synthesis of 2,6-diaryl-4-oxo-N,N&prime
di(pyridin-2-yl)cyclohexane-1,1-dicarboxamide is described in this present study, which occurs through a double Michael addition reaction between diamide and vario

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c8b8630ffd698aaa7a1860c8aff1b4
https://www.mdpi.com/1420-3049/24/7/1332