Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Saleh A. Naser"'
Autor:
Noah Greenman, Latifa S. Abdelli, Sayf Al-Deen Hassouneh, Sobur Ali, Catherine Johnston, Saleh A. Naser, Taj Azarian
Publikováno v:
Frontiers in Microbiomes, Vol 3 (2024)
Propionic acid (PPA), an anti-fungal agent and common food additive, has been shown to induce atypical neurodevelopment in mice, accompanied by gastrointestinal dysfunction potentially resulting from gut dysbiosis. A putative association between diet
Externí odkaz:
https://doaj.org/article/40e75a591aa94937bb8c6e6344c80efa
Autor:
Ala’ Alhendi, Saleh A. Naser
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Like TNFα, IL-6 is upregulated in Crohn’s disease (CD) especially in patients associated with Mycobacterium avium paratuberculosis (MAP) infection, and both cytokines have been targeted as a therapeutic option for the treatment of the disease desp
Externí odkaz:
https://doaj.org/article/199a268ed1d941b198d129c0b1dcbe58
Autor:
David Y. Graham, Saleh A. Naser, Thomas Borody, Zbigniew Hebzda, Harry Sarles, Scott Levenson, Robert Hardi, Tomasz Arłukowicz, Petar Svorcan, Reza Fathi, Aida Bibliowicz, Patricia Anderson, Patrick McLean, Clara Fehrmann, M. Scott Harris, Shuhong Zhao, Ira N. Kalfus
Publikováno v:
Antibiotics, Vol 13, Iss 8, p 694 (2024)
This study, conducted between 4 October 2013, and 30 November 2018, tested the hypothesis that triple antimicrobial therapy, targeting Mycobacterium avium subspecies paratuberculosis (MAP), long considered a putative cause, would favorably affect Cro
Externí odkaz:
https://doaj.org/article/e2493f4da86e452f9ac5eb4e6ef7ff2d
Autor:
J. Todd Kuenstner, Qiang Xu, Tim J. Bull, Antonio C. G. Foddai, Irene R. Grant, Saleh A. Naser, Raghava Potula, Peilin Zhang, Ira Shafran, Serhat Emre Akhanli, Svetlana Khaiboullina, Russell Kruzelock
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Objectives1) Culture Mycobacterium avium ssp. paratuberculosis (MAP)from blood, 2) assess infection persistence, 3) determine Crohn’s disease (CD) cytokine expression, 4) compare CD cytokine expression to tuberculosis, and 5) perform a meta-analysi
Externí odkaz:
https://doaj.org/article/ca62cd70a0e0441c8d776c8eaaa54a26
Autor:
Ala’ Alhendi, Saleh A. Naser
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Interleukin-6 (IL-6) is a key mediator cytokine of the immune response as well as a regulator of many physiological and pathological processes. In Crohn’s disease (CD), cytokine imbalance rules the intestinal microenvironment and leads to chronic i
Externí odkaz:
https://doaj.org/article/b2bcac04059c40dbb4d82b6434460976
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Serotonin (5-hydroxytryptamine [5-HT]) is an intestinal neuromodulator that regulates several essential enteric physiological functions such as absorption or secretion of fluids, and peristaltic reflexes. Availability of the intestinal 5-HT
Externí odkaz:
https://doaj.org/article/2b581d68cdc2408e8698a517bf9bfa00
Publikováno v:
Current Issues in Molecular Biology, Vol 43, Iss 2, Pp 728-748 (2021)
The ongoing coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a severe threat to human health and the global economy and has resulted in overwhelming stress on health care systems wor
Externí odkaz:
https://doaj.org/article/de74b14b52324fefa20049117b0df655
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
TNFα converting enzyme (TACE) is a transmembrane metalloprotease that sheds an assortment of signaling receptors, cytokines, growth factors, and pro-inflammatory mediators. In Crohn’s disease (CD), TACE activity is upregulated, resulting in a mark
Externí odkaz:
https://doaj.org/article/64b067a8c8d84adabe734e331480e852
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Vitamin D is a key regulator in calcium and phosphorus metabolism which are essential for maintaining bone health. Recent reports also showed a role for vitamin D in immune regulation which may be linked to vitamin D deficiency in autoimmune disorder
Externí odkaz:
https://doaj.org/article/4b7f55b0b43d48fca09181732e5a7166
Autor:
Esra’a Keewan, Saleh A. Naser
Publikováno v:
Gut Pathogens, Vol 12, Iss 1, Pp 1-10 (2020)
Abstract Background MiR-146a, an effector mediator, targets Notch-1 and regulates the innate and adaptive immune systems response. Recently, we reported that Notch-1 signaling plays a key role in macrophage polarization and response during infection.
Externí odkaz:
https://doaj.org/article/056b021d9e4b4f459d93120c5d98c846