FANCD2-FANCI surveys DNA and recognizes double- to single-stranded junctions.

Autor: Alcón P; MRC Laboratory of Molecular Biology, Cambridge, UK., Kaczmarczyk AP; Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK., Ray KK; Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK., Liolios T; Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, The Netherlands., Guilbaud G; MRC Laboratory of Molecular Biology, Cambridge, UK., Sijacki T; MRC Laboratory of Molecular Biology, Cambridge, UK., Shen Y; MRC Laboratory of Molecular Biology, Cambridge, UK., McLaughlin SH; MRC Laboratory of Molecular Biology, Cambridge, UK., Sale JE; MRC Laboratory of Molecular Biology, Cambridge, UK., Knipscheer P; Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, The Netherlands., Rueda DS; Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK. david.rueda@imperial.ac.uk.; MRC Laboratory of Medical Sciences, London, UK. david.rueda@imperial.ac.uk., Passmore LA; MRC Laboratory of Molecular Biology, Cambridge, UK. passmore@mrc-lmb.cam.ac.uk.

Publikováno v: Nature [Nature] 2024 Aug; Vol. 632 (8027), pp. 1165-1173. Date of Electronic Publication: 2024 Jul 31.

Fifty years of Nucleic Acids Research.

Autor: Sale JE; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK., Stoddard BL; Division of Basic Sciences, Fred Hutchinson Cancer Center, 1100 Fairview Ave. N., Seattle WA 98109, USA.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 Jan 11; Vol. 52 (1), pp. 1-3.

Continuous synthesis of E. coli genome sections and Mb-scale human DNA assembly.

Autor: Zürcher JF; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK., Kleefeldt AA; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK., Funke LFH; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.; Department of Biomedical Engineering, National University of Singapore, Singapore, Singapore., Birnbaum J; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK., Fredens J; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.; Synthetic Biology for Clinical and Technological Innovation, Department of Biochemistry, National University of Singapore, Singapore, Singapore., Grazioli S; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK., Liu KC; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK., Spinck M; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK., Petris G; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.; Wellcome Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Murat P; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK., Rehm FBH; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK., Sale JE; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK., Chin JW; Medical Research Council Laboratory of Molecular Biology, Cambridge, UK. chin@mrc-lmb.cam.ac.uk.

Publikováno v: Nature [Nature] 2023 Jul; Vol. 619 (7970), pp. 555-562. Date of Electronic Publication: 2023 Jun 28.

DNA replication initiation shapes the mutational landscape and expression of the human genome.

Autor: Murat P; Division of Protein & Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK., Perez C; Division of Protein & Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK., Crisp A; Division of Protein & Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK., van Eijk P; Broken String Biosciences Ltd., BioData Innovation Centre, Unit AB3-03, Level 3, Wellcome Genome Campus, Hinxton, Cambridge CB10 1DR, UK.; Division of Cancer & Genetics School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK., Reed SH; Broken String Biosciences Ltd., BioData Innovation Centre, Unit AB3-03, Level 3, Wellcome Genome Campus, Hinxton, Cambridge CB10 1DR, UK.; Division of Cancer & Genetics School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK., Guilbaud G; Division of Protein & Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK., Sale JE; Division of Protein & Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.

Publikováno v: Science advances [Sci Adv] 2022 Nov 11; Vol. 8 (45), pp. eadd3686. Date of Electronic Publication: 2022 Nov 09.

Creation and resolution of non-B-DNA structural impediments during replication.

Autor: Mellor C; Division of Protein & Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Cambridge, UK., Perez C; Division of Protein & Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Cambridge, UK., Sale JE; Division of Protein & Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Cambridge, UK.

Publikováno v: Critical reviews in biochemistry and molecular biology [Crit Rev Biochem Mol Biol] 2022 Aug; Vol. 57 (4), pp. 412-442. Date of Electronic Publication: 2022 Sep 28.