Posttranslational modifications of proteins are key features in the identification of CSF biomarkers of multiple sclerosis.

Autor: Salazar IL; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.; Institute for Interdisciplinary Research, University of Coimbra, Coimbra, Portugal., Lourenço AST; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.; Institute for Interdisciplinary Research, University of Coimbra, Coimbra, Portugal., Manadas B; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.; Institute for Interdisciplinary Research, University of Coimbra, Coimbra, Portugal., Baldeiras I; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, Coimbra, Portugal., Ferreira C; Coimbra Chemistry Centre, Department of Chemistry, University of Coimbra, Coimbra, Portugal., Teixeira AC; Molecular Neurobiology Group, Instituto de Biologia Molecular e Celular (IBMC), Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal., Mendes VM; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal., Novo AM; Neurology Department, CHUC-Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal., Machado R; Neurology Department, CHUC-Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal., Batista S; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.; Neurology Department, CHUC-Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal., Macário MDC; Neurology Department, CHUC-Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal., Grãos M; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.; Institute for Interdisciplinary Research, University of Coimbra, Coimbra, Portugal.; Biocant-Associação de Transferência de Tecnologia, Cantanhede, Portugal., Sousa L; Neurology Department, CHUC-Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal., Saraiva MJ; Molecular Neurobiology Group, Instituto de Biologia Molecular e Celular (IBMC), Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal., Pais AACC; Coimbra Chemistry Centre, Department of Chemistry, University of Coimbra, Coimbra, Portugal., Duarte CB; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal. cbduarte@ci.uc.pt.; Department of Life Sciences, University of Coimbra, Coimbra, Portugal. cbduarte@ci.uc.pt.

Publikováno v: Journal of neuroinflammation [J Neuroinflammation] 2022 Feb 08; Vol. 19 (1), pp. 44. Date of Electronic Publication: 2022 Feb 08.

BDNF-Live-Exon-Visualization (BLEV) Allows Differential Detection of BDNF Transcripts in vitro and in vivo .

Autor: Singer W; Department of Otolaryngology, Tübingen Hearing Research Centre (THRC), Molecular Physiology of Hearing, University of Tübingen, Tübingen, Germany., Manthey M; Department of Otolaryngology, Tübingen Hearing Research Centre (THRC), Molecular Physiology of Hearing, University of Tübingen, Tübingen, Germany., Panford-Walsh R; Department of Otolaryngology, Tübingen Hearing Research Centre (THRC), Molecular Physiology of Hearing, University of Tübingen, Tübingen, Germany., Matt L; Department of Pharmacology, Institute of Pharmacy, Toxicology and Clinical Pharmacy, University of Tübingen, Tübingen, Germany., Geisler HS; Department of Otolaryngology, Tübingen Hearing Research Centre (THRC), Molecular Physiology of Hearing, University of Tübingen, Tübingen, Germany., Passeri E; Department of Otolaryngology, Tübingen Hearing Research Centre (THRC), Molecular Physiology of Hearing, University of Tübingen, Tübingen, Germany., Baj G; B.R.A.I.N. Centre for Neuroscience, Department of Life Sciences, University of Trieste, Trieste, Italy., Tongiorgi E; B.R.A.I.N. Centre for Neuroscience, Department of Life Sciences, University of Trieste, Trieste, Italy., Leal G; Centre for Neuroscience and Cell Biology (CNC), Department of Life Sciences, University of Coimbra, Coimbra, Portugal., Duarte CB; Centre for Neuroscience and Cell Biology (CNC), Department of Life Sciences, University of Coimbra, Coimbra, Portugal., Salazar IL; Centre for Neuroscience and Cell Biology (CNC), Department of Life Sciences, University of Coimbra, Coimbra, Portugal., Eckert P; Department of Otolaryngology, Tübingen Hearing Research Centre (THRC), Molecular Physiology of Hearing, University of Tübingen, Tübingen, Germany., Rohbock K; Department of Otolaryngology, Tübingen Hearing Research Centre (THRC), Molecular Physiology of Hearing, University of Tübingen, Tübingen, Germany., Hu J; Centre for Integrative Neuroscience (CIN), University of Tübingen, Tübingen, Germany., Strotmann J; Department of Physiology, Institute of Physiology, University of Hohenheim, Stuttgart, Germany., Ruth P; Department of Pharmacology, Institute of Pharmacy, Toxicology and Clinical Pharmacy, University of Tübingen, Tübingen, Germany., Zimmermann U; Department of Otolaryngology, Tübingen Hearing Research Centre (THRC), Molecular Physiology of Hearing, University of Tübingen, Tübingen, Germany., Rüttiger L; Department of Otolaryngology, Tübingen Hearing Research Centre (THRC), Molecular Physiology of Hearing, University of Tübingen, Tübingen, Germany., Ott T; Transgenic Facility Tübingen, University of Tübingen, Tübingen, Germany., Schimmang T; Instituto de Biologíay Genética Molecular, Universidad de Valladolid y Consejo Superior de Investigaciones Científicas, Valladolid, Spain., Knipper M; Department of Otolaryngology, Tübingen Hearing Research Centre (THRC), Molecular Physiology of Hearing, University of Tübingen, Tübingen, Germany.

Publikováno v: Frontiers in molecular neuroscience [Front Mol Neurosci] 2018 Sep 27; Vol. 11, pp. 325. Date of Electronic Publication: 2018 Sep 27 (Print Publication: 2018).

Erratum to "Calpains and neuronal damage in the ischemic brain: The swiss knife in synaptic injury" [Progress in Neurobiology 143 (2016) 1-35].

Autor: Curcio M; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Salazar IL; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal; Doctoral Programme in Experimental Biology and Biomedicine, Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal; Institute for Interdisciplinary Research, University of Coimbra (IIIUC), 3030-789 Coimbra, Portugal., Mele M; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Canzoniero LM; Department of Science and Technology, University of Sannio, 82100 Benevento, Italy., Duarte CB; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal; Department of Life Sciences, University of Coimbra, 3000-456 Coimbra, Portugal. Electronic address: cbduarte@ci.uc.pt.

Publikováno v: Progress in neurobiology [Prog Neurobiol] 2016 Dec; Vol. 147, pp. 20. Date of Electronic Publication: 2016 Sep 05.

The Role of Proteases in Hippocampal Synaptic Plasticity: Putting Together Small Pieces of a Complex Puzzle.

Autor: Salazar IL; Faculty of Medicine (Polo I), Center for Neuroscience and Cell Biology, University of Coimbra, Rua Larga, 3004-504, Coimbra, Portugal.; Doctoral Programme in Experimental Biology and Biomedicine, Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504, Coimbra, Portugal.; Institute for Interdisciplinary Research (IIIUC), University of Coimbra, 3030-789, Coimbra, Portugal., Caldeira MV; Faculty of Medicine (Polo I), Center for Neuroscience and Cell Biology, University of Coimbra, Rua Larga, 3004-504, Coimbra, Portugal.; Institute for Interdisciplinary Research (IIIUC), University of Coimbra, 3030-789, Coimbra, Portugal., Curcio M; Faculty of Medicine (Polo I), Center for Neuroscience and Cell Biology, University of Coimbra, Rua Larga, 3004-504, Coimbra, Portugal.; Laboratory for Axon Growth and Regeneration, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Duarte CB; Faculty of Medicine (Polo I), Center for Neuroscience and Cell Biology, University of Coimbra, Rua Larga, 3004-504, Coimbra, Portugal. cbduarte@ci.uc.pt.; Department of Life Sciences, University of Coimbra, 3000-456, Coimbra, Portugal. cbduarte@ci.uc.pt.

Publikováno v: Neurochemical research [Neurochem Res] 2016 Feb; Vol. 41 (1-2), pp. 156-82. Date of Electronic Publication: 2015 Nov 07.

Brain ischemia downregulates the neuroprotective GDNF-Ret signaling by a calpain-dependent mechanism in cultured hippocampal neurons.

Autor: Curcio M; 1] CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra 3004-504, Portugal [2] Department of Science and Technology, University of Sannio, Benevento 82100, Italy., Salazar IL; 1] CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra 3004-504, Portugal [2] Doctoral Programme in Experimental Biology and Biomedicine, Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal [3] Institute for Interdisciplinary Research, University of Coimbra (IIIUC), Coimbra, Portugal., Inácio AR; Wallenberg Neuroscience Center, Lund University, Lund 221 84, Sweden., Duarte EP; 1] CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra 3004-504, Portugal [2] Department of Life Sciences, University of Coimbra, Coimbra 3004-517, Portugal., Canzoniero LM; Department of Science and Technology, University of Sannio, Benevento 82100, Italy., Duarte CB; 1] CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra 3004-504, Portugal [2] Department of Life Sciences, University of Coimbra, Coimbra 3004-517, Portugal.

Publikováno v: Cell death & disease [Cell Death Dis] 2015 Feb 12; Vol. 6, pp. e1645. Date of Electronic Publication: 2015 Feb 12.