Early Neuro-Deterioration and Mortality Among Neurology Inpatients in a Zambian Referral Hospital: A Prospective Cohort Study.

Autor: Prust ML; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Kaunda K; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Salasky V; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Mateyo K; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Bwalya M; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Chilando M; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Luchembe M; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Nassoro D; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Munkombwe D; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Namangala C; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Mwamba J; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Simushi F; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Yankae L; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Kinkata M; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Perez G; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Pradhyuman H; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Awaris M; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Braun S; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Chishimba L; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Chomba M; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Peloso A; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Zimba S; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Mumba N; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD., Saylor DR; From the Department of Neurology (M.L.P.), Yale School of Medicine, New Haven, CT; University Teaching Hospital (K.K., M.K.), Lusaka, Zambia; Department of Neurology (V.S.), University of Maryland School of Medicine, Baltimore, MD; Department of Medicine (K.M., M.B., M. Chilando, M.L., D.N., D.M., C.N., J.M., F.S., L.Y., M.A., S.B., L.C., M. Chomba, S.Z., N.M., D.R.S.), University of Zambia School of Medicine, Lusaka; University of Miami School of Medicine (G.P., H.P.), FL; Queen's University (A.P.), Kingston, Ontario, Canada; and Department of Neurology (D.R.S.), Johns Hopkins University School of Medicine, Baltimore, MD.

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