Metabolomic Profiling of Red Blood Cells to Identify Molecular Markers of Methotrexate Response in the Collagen Induced Arthritis Mouse Model.

Autor: Salamoun, Yezan M.¹ ymsalamoun@ku.edu, Polireddy, Kishore¹, Cho, Yu Kyoung¹, Funk, Ryan Sol^1,2 ymsalamoun@ku.edu

Publikováno v: Future Pharmacology. Dec2022, Vol. 2 Issue 4, p625-641. 17p.

Methotrexate Disposition, Anti-Folate Activity, and Metabolomic Profiling to Identify Molecular Markers of Disease Activity and Drug Response in the Collagen-Induced Arthritis Mouse Model.

Autor: Salamoun YM; Department of Pharmacy Practice, University of Kansas Medical Center, Kansas City, KS 66160, USA., Polireddy K; Department of Pharmacy Practice, University of Kansas Medical Center, Kansas City, KS 66160, USA., Cho YK; Department of Pharmacy Practice, University of Kansas Medical Center, Kansas City, KS 66160, USA., Medcalf MR; Department of Pharmacy Practice, University of Kansas Medical Center, Kansas City, KS 66160, USA., Funk RS; Department of Pharmacy Practice, University of Kansas Medical Center, Kansas City, KS 66160, USA.; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA.

Publikováno v: Metabolites [Metabolites] 2021 Dec 28; Vol. 12 (1). Date of Electronic Publication: 2021 Dec 28.