Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Salah, Amasheh"'
Publikováno v:
Materials Today Bio, Vol 23, Iss , Pp 100808- (2023)
Cannabis-based biomaterials have the potential to deliver anti-inflammatory therapeutics specifically to desired cells, tissues, and organs, enhancing drug delivery and the effectiveness of anti-inflammatory treatment while minimizing toxicity. As a
Externí odkaz:
https://doaj.org/article/87da1bd29932411aacd4fc4a6b023a85
Publikováno v:
Membranes, Vol 14, Iss 2, p 40 (2024)
Analysis of secondary plant compounds for the development of novel therapies is a common focus of experimental biomedicine. Currently, multiple health-supporting properties of plant-derived molecules are known but still information on many mechanisms
Externí odkaz:
https://doaj.org/article/b855cd3a04494ff4a12c232741e3ed3a
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1530 (2024)
Peyer’s patches (PPs) are part of the gut-associated lymphatic tissue (GALT) and represent the first line of the intestinal immunological defense. They consist of follicles with lymphocytes and an overlying subepithelial dome with dendritic cells a
Externí odkaz:
https://doaj.org/article/fb102ca6d8cc401ea0d314d2aa84bb29
Publikováno v:
Membranes, Vol 14, Iss 1, p 18 (2024)
Cannabidiol (CBD), the non-psychoactive compound derived from the cannabis plant, has gained attention in recent years as a remedy against gastrointestinal disorders ranging from nausea and inflammation to abdominal pain. Recent advances demonstrated
Externí odkaz:
https://doaj.org/article/a470aad62c454fcfbb484fbd00f8e2e0
Autor:
Alexander G. Markov, Anastasia E. Bikmurzina, Arina A. Fedorova, Ekaterina P. Vinogradova, Natalia M. Kruglova, Igor I. Krivoi, Salah Amasheh
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 276 (2023)
Endothelial cells in brain capillaries are crucial for the function of the blood–brain barrier (BBB), and members of the tight junction protein family of claudins are regarded to be primarily responsible for barrier properties. Thus, the analysis o
Externí odkaz:
https://doaj.org/article/c89420c740f1491fa1150c60711f9ef5
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The proinflammatory cytokine tumor necrosis factor (TNF) has been described as one of the main mediators of intestinal inflammatory diseases, affecting the composition of tight junction (TJ) proteins and leading to a disruption of the epithelial barr
Externí odkaz:
https://doaj.org/article/ec60639bd78243f586abcf5a846f8e5f
Publikováno v:
Physiological Reports, Vol 10, Iss 7, Pp n/a-n/a (2022)
Abstract The plant alkaloid berberine has been shown to have many beneficial effects on human health. This has led to its use as a treatment for various cancer types, obesity, and diabetes. Moreover, a described barrier‐strengthening effect in huma
Externí odkaz:
https://doaj.org/article/7f6917dc894d41e5b6394ec6a9d561f3
Autor:
Viktoria Bekusova, Tatiana Zudova, Ilyas Fatyykhov, Arina Fedorova, Salah Amasheh, Alexander G. Markov
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15610 (2022)
Recently it has been reported that the tumor adjacent colon tissues of 1,2-dymethylhydrazine induced (DMH)-rats revealed a high paracellular permeability. We hypothesized that the changes might be induced by cytokines. Colorectal cancer is accompanie
Externí odkaz:
https://doaj.org/article/fbb6a697f7da434d80a5320d8691f640
Publikováno v:
Membranes, Vol 12, Iss 8, p 731 (2022)
The epithelial barrier is crucial for proper gastrointestinal function, preventing the unwanted passage of solutes and therefore representing a prerequisite for vectorial transport. Claudin-4 and claudin-18.2, two critical tight junction proteins of
Externí odkaz:
https://doaj.org/article/517538fd0ec44a618322b73ffa3894f2
Autor:
Nora Brunner, Laura Stein, Valeria Cornelius, Ria Knittel, Petra Fallier-Becker, Salah Amasheh
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Claudin-5 determines the sealing properties of blood-brain barrier tight junctions and its function is impaired in neurodegenerative and neuroinflammatory disorders. Focusing on the contribution of claudin-5 to the trans-interaction within the tight
Externí odkaz:
https://doaj.org/article/31a92232b95844b29ba0e8ad39c4460a