Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Sakurako Goto-Ito"'
Autor:
Maiko Wakita, Atsushi Yamagata, Tomoko Shiroshima, Hironori Izumi, Asami Maeda, Mizuki Sendo, Ayako Imai, Keiko Kubota, Sakurako Goto-Ito, Yusuke Sato, Hisashi Mori, Tomoyuki Yoshida, Shuya Fukai
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Synaptic organizers are cell-adhesion molecules capable of inducing synaptic differentiation through transsynaptic interactions. Here the authors present the crystal structure of the intracellular interaction between the synaptic organizer PTPδ and
Externí odkaz:
https://doaj.org/article/f3a3b04487b0410792c518a75d28e75e
Autor:
Atsushi Yamagata, Sakurako Goto-Ito, Yusuke Sato, Tomoko Shiroshima, Asami Maeda, Masahiko Watanabe, Takashi Saitoh, Katsumi Maenaka, Tohru Terada, Tomoyuki Yoshida, Takeshi Uemura, Shuya Fukai
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) function as postsynaptic organizers that induce excitatory synapses. Here authors solve the crystal structure of LRRTM2 in complex with its ligand Nrxn1β and shed light on how selective bi
Externí odkaz:
https://doaj.org/article/6a3dc0e46ef84edea9ccf79ebc62bca0
Autor:
Atsushi Yamagata, Yuri Miyazaki, Norihiko Yokoi, Hideki Shigematsu, Yusuke Sato, Sakurako Goto-Ito, Asami Maeda, Teppei Goto, Makoto Sanbo, Masumi Hirabayashi, Mikako Shirouzu, Yuko Fukata, Masaki Fukata, Shuya Fukai
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
LGI1 is an epilepsy-related gene that encodes a secreted neuronal protein. Here the authors present the crystal structure of LGI1 bound to its receptor ADAM22, which provides structural insights into epilepsy-causing LGI1 mutations and might facilita
Externí odkaz:
https://doaj.org/article/c8d56a79c67b43399c581db013e3959e
Autor:
Sakurako Goto-Ito, Atsushi Yamagata, Yusuke Sato, Takeshi Uemura, Tomoko Shiroshima, Asami Maeda, Ayako Imai, Hisashi Mori, Tomoyuki Yoshida, Shuya Fukai
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Synaptic organizers are cell adhesion molecules that facilitate synapse formation through trans-synaptic interactions. Here the authors give molecular insights into synaptic differentiation by determining the structures of the synaptic adhesion-like
Externí odkaz:
https://doaj.org/article/419e3942d7884c3195337cfa2debe0b8
Autor:
Tomio S. Takahashi, Yoshihiro Hirade, Aya Toma, Yusuke Sato, Atsushi Yamagata, Sakurako Goto-Ito, Akiko Tomita, Shinichiro Nakada, Shuya Fukai
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
E3 ubiquitin ligase RNF168 is important for the repair of DNA double-strand breaks and recognizes ubiquitylated targets through two Ub-dependent DSB recruitment modules UDM1 and UDM2. Here the authors combine crystallography, cell biology and biochem
Externí odkaz:
https://doaj.org/article/844a6cbf8e1c4c36836921bf75e0a576
Autor:
Aya Toma, Tomio S Takahashi, Yusuke Sato, Atsushi Yamagata, Sakurako Goto-Ito, Shinichiro Nakada, Atsuhiko Fukuto, Yasunori Horikoshi, Satoshi Tashiro, Shuya Fukai
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120887 (2015)
Several ubiquitin-binding zinc fingers (UBZs) have been reported to preferentially bind K63-linked ubiquitin chains. In particular, the UBZ domain of FAAP20 (FAAP20-UBZ), a member of the Fanconi anemia core complex, seems to recognize K63-linked ubiq
Externí odkaz:
https://doaj.org/article/4ccb40b8a46a438cb79940c55d7059e7
Autor:
Jinglei Cheng, Ryutaro Shirakawa, Shonosuke Wakayama, Hiroshi Masumoto, Sakurako Goto-Ito, Haremaru Kubo, Duc Anh Trinh, Yusuke Sato, Hisanori Horiuchi, Toyoshi Fujimoto, Shuya Fukai, Kota Goto, Atsushi Yamagata, Natsumi Sakata
Publikováno v:
EMBO J
Protein prenylation is essential for many cellular processes including signal transduction, cytoskeletal reorganization, and membrane trafficking. Here, we identify a novel type of protein prenyltransferase, which we named geranylgeranyltransferase t
Autor:
Shuya Fukai, Atsushi Yamagata, Takeshi Uemura, Katsumi Maenaka, Takashi Saitoh, Sakurako Goto-Ito, Asami Maeda, Masahiko Watanabe, Tomoko Shiroshima, Tomoyuki Yoshida, Tohru Terada, Yusuke Sato
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) function as postsynaptic organizers that induce excitatory synapses. Neurexins (Nrxns) and heparan sulfate proteoglycans have been identified as presynaptic ligands for LRRTMs. Specifically
Publikováno v:
Biomolecules (2218-273X). Mar2017, Vol. 7 Issue 1, p32. 10p.
Autor:
Yasushi Saeki, Keiji Tanaka, Minoru Ishikawa, Sakurako Goto-Ito, Noriyuki Matsuda, Atsushi Yamagata, Yusuke Sato, Koji Yamano, Shuya Fukai, Kei Okatsu, Ai Kaiho, Yuichi Hashimoto
Publikováno v:
Nature Structural & Molecular Biology. 24:911-919
Parkin ubiquitin (Ub) ligase (also known as PARK2) ubiquitinates damaged mitochondria for their clearance and quality control. USP30 deubiquitinase opposes parkin-mediated Ub-chain formation on mitochondria by preferentially cleaving Lys6-linked Ub c