Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sakura Saito"'
Autor:
Yoshiyuki Nagai, Sakura Saito, Masayoshi Kohase, Michiko Hishiyama, Yukano Ohnishi, Masato Tashiro, Atsushi Kato
Publikováno v:
Journal of Virology. 76:7114-7124
The Sendai virus C proteins, C′, C, Y1, and Y2, are a nested set of independently initiated carboxy-coterminal proteins translated from a reading frame overlapping the P frame on the P mRNA. The C proteins are extremely versatile and have been show
Publikováno v:
Virology. 293(2):205-209
Sendai virus C protein (SeV C) has been reported to counteract the antiviral activities of interferons (IFNs) by inhibiting the expression of IFN-stimulated gene products. In SeV C-expressing cells, formation of an active ISGF3 complex and translocat
Autor:
Sakura Saito, Yoshiyuki Nagai, Atsushi Kato, Yukano Ohnishi, Masato Tashiro, Masayoshi Kohase
Publikováno v:
Journal of Virology. 75:3802-3810
An open reading frame (ORF) overlapping the amino-terminal portion of the Sendai virus (SeV) P ORF in the +1 frame produces a nested set of carboxy-coterminal proteins, C′, C, Y1, and Y2, which are referred to collectively as the C proteins. The C
Publikováno v:
Journal of Virology. 73:2425-2433
A short model genome RNA and also the genome RNA of influenza A virus bearing both 5′- and 3′-terminal common sequences activated the interferon-induced double-stranded-RNA-dependent protein kinase, PKR, by stimulating autophosphorylation in vitr
Autor:
Yoshihiro Hayakawa, Sakura Saito, Seiya Kohno, Ryoji Noyori, Akihiro Tominaga, Katsukiyo Sakurai
Publikováno v:
Microbiology and Immunology. 34:737-747
Dephosphorylated "core" of 2',5'-oligoadenylate (2-5A) dimer (A2'p5'A), exogenously added to nonpermeabilized FL cells, inhibited the multiplication of Sindbis virus and vesicular stomatitis virus (VSV). The compound was shown to inhibit viral protei
Publikováno v:
Journal of biochemistry. 135(4)
Eukaryotic initiation factor 2 (eIF2) is a heterotrimeric protein composed of alpha, beta, and gamma subunits, of which the alpha subunit (eIF2 alpha) plays a crucial role in regulation of protein synthesis through phosphorylation at Ser51. All three
Autor:
Sakura Saito, Naoko Miyajima, Masayoshi Kohase, Yoshiharu Matsuura, Tatsuo Miyamura, Hideki Aizaki, Toshio Ogino, Takashi Harada
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 20(12)
To elucidate the mechanism of the persistent nature of hepatitis C virus (HCV) infection, we examined whether the expression of HCV proteins affect the antiviral activity of interferon (IFN). Antiviral activity of IFN in HepG2 cells expressing all HC
Autor:
Sakura Saito, Masao Kawakita
Publikováno v:
Microbiology and immunology. 35(12)
In FL cells, interferon (IFN)-induced dsRNA-dependent protein kinase (PK-I) was found to be present in a form complexed with a potent inhibitor of its dsRNA-dependent activation. The inhibitor was readily dissociated from PK-I by DEAE-cellulose chrom
Publikováno v:
Journal of General Virology. 64:2017-2020
Summary The presence of a low level of interferon (IFN) activity was demonstrated in aged culture medium of primary chick embryo (CE) cells. The endogenous cytoplasmic level of 2′,5′-oligoadenylate (2′,5′-A) synthetase activity also increased
Autor:
Yasuyuki Ogura, Sakura Saito-Wakiyama
Publikováno v:
Japanese Journal of Medical Science and Biology. 30:125-135
Presence of chloramphenicol in the growth medium for mycelia of Aspergillus oryzae was without effect on the oxidative activity, respiratory control, or P/O ratio of isolated mitochondria. The mitochondria oxidized Krebs cycle intermediates even in t