Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Saku, Ruohonen"'
Autor:
Behnoush Gustafsson, Suvi P. Rovio, Saku Ruohonen, Nina Hutri-Kähönen, Mika Kähönen, Jorma S. A. Viikari, Katja Pahkala, Olli T. Raitakari
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Epicardial adipose tissue (EAT) is the cardiac visceral fat depot proposed to play a role in the etiology of various cardiovascular disease outcomes. Little is known about EAT determinants in a general population. We examined cardiometabolic
Externí odkaz:
https://doaj.org/article/faa77fef5e5f454ea7b85c7d52929091
Autor:
Gabin Drouard, Juha Mykkänen, Jarkko Heiskanen, Joona Pohjonen, Saku Ruohonen, Katja Pahkala, Terho Lehtimäki, Xiaoling Wang, Miina Ollikainen, Samuli Ripatti, Matti Pirinen, Olli Raitakari, Jaakko Kaprio
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background Machine learning (ML) classifiers are increasingly used for predicting cardiovascular disease (CVD) and related risk factors using omics data, although these outcomes often exhibit categorical nature and class imbalances. However,
Externí odkaz:
https://doaj.org/article/90c753918c9f424a824506ed900513e9
Autor:
Jukka Pihlman, Costan G. Magnussen, Tomi T. Laitinen, Saku Ruohonen, Katja Pahkala, Eero Jokinen, Tomi P. Laitinen, Nina Hutri-Kähönen, Päivi Tossavainen, Leena Taittonen, Mika Kähönen, Jorma SA. Viikari, Olli T. Raitakari, Markus Juonala, Joel Nuotio
Publikováno v:
International Journal of Cardiology. Cardiovascular Risk and Prevention, Vol 20, Iss , Pp 200227- (2024)
To investigate the association of number of siblings with preclinical cardiovascular disease (CVD) markers in adulthood.The sample comprised 2776 participants (54 % female) from the Cardiovascular Risk in Young Finns Study who had CVD risk factor dat
Externí odkaz:
https://doaj.org/article/ec141f9cc8514fea936f07ce586b20e4
Autor:
Jarkko S. Heiskanen, Jussi A. Hernesniemi, Saku Ruohonen, Nina Hutri-Kähönen, Mika Kähönen, Eero Jokinen, Päivi Tossavainen, Merja Kallio, Tomi Laitinen, Terho Lehtimäki, Jorma Viikari, Markus Juonala, Jaakko Nevalainen, Olli T. Raitakari
Publikováno v:
Annals of Medicine, Vol 53, Iss 1, Pp 160-168 (2021)
AbstractBackground Increased left ventricular mass (LVM) predicts cardiovascular events and mortality. The objective of this study was to determine whether early-life exposures to body mass index (BMI) and systolic blood pressure (SPB) affects the le
Externí odkaz:
https://doaj.org/article/eec8b068ee4941df88902c8e4c639446
Autor:
Anni Suominen, Guillem Saldo Rubio, Saku Ruohonen, Zoltán Szabó, Lotta Pohjolainen, Bishwa Ghimire, Suvi T. Ruohonen, Karla Saukkonen, Jani Ijas, Sini Skarp, Leena Kaikkonen, Minying Cai, Sharon L. Wardlaw, Heikki Ruskoaho, Virpi Talman, Eriika Savontaus, Risto Kerkelä, Petteri Rinne
Backgroundα-Melanocyte-stimulating hormone (α-MSH) regulates diverse physiological functions by activating melanocortin receptors (MC-R). α-MSH is predominantly expressed in the pituitary gland, but it is also found in several peripheral tissues s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30016c0bf2a37facb0826939534ff5cf
https://doi.org/10.1101/2023.04.06.535956
https://doi.org/10.1101/2023.04.06.535956
Autor:
Francine Z. Marques, Priscilla R. Prestes, Sean G. Byars, Scott C. Ritchie, Peter Würtz, Sheila K. Patel, Scott A. Booth, Indrajeetsinh Rana, Yosuke Minoda, Stuart P. Berzins, Claire L. Curl, James R. Bell, Bryan Wai, Piyush M. Srivastava, Antti J. Kangas, Pasi Soininen, Saku Ruohonen, Mika Kähönen, Terho Lehtimäki, Emma Raitoharju, Aki Havulinna, Markus Perola, Olli Raitakari, Veikko Salomaa, Mika Ala‐Korpela, Johannes Kettunen, Maree McGlynn, Jason Kelly, Mary E. Wlodek, Paul A. Lewandowski, Lea M. Delbridge, Louise M. Burrell, Michael Inouye, Stephen B. Harrap, Fadi J. Charchar
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 6 (2017)
BackgroundCardiac hypertrophy increases the risk of developing heart failure and cardiovascular death. The neutrophil inflammatory protein, lipocalin‐2 (LCN2/NGAL), is elevated in certain forms of cardiac hypertrophy and acute heart failure. Howeve
Externí odkaz:
https://doaj.org/article/f5430b2a41554e029fc2eb74411dd1ef
Publikováno v:
Toxicologic pathology. 50(6)
As regulators of homeostasis, astrocytes undergo morphological changes after injury to limit the insult in central nervous system (CNS). Trimethyltin (TMT) is a known neurotoxicant that induces reactive astrogliosis in rat CNS. To evaluate the degree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a64cbe39a861311ef9ac237758626d
https://pubmed.ncbi.nlm.nih.gov/36125102
https://pubmed.ncbi.nlm.nih.gov/36125102
Autor:
Yoriko Heianza, Hao Ma, Lu Qi, Vivian Fonseca, Xiang Li, Jarkko S. Heiskanen, Lydia A. Bazzano, Olli T. Raitakari, Saku Ruohonen, Emily W. Harville, Yajun Guo, Hua He, Tanika N. Kelly, Nina Hutri-Kähönen, Wei Chen
Publikováno v:
Journal of Hypertension. 39:961-969
OBJECTIVES Heart disease is the most common cause of death in patients with nonalcoholic fatty liver disease (NAFLD). Emerging data have shown that NAFLD may affect subclinical myocardial remodeling, mainly left ventricular hypertrophy; however, evid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79aeccb5dc7b7e6410a6057cbfab43df
https://doi.org/10.1097/hjh.0000000000002716
https://doi.org/10.1097/hjh.0000000000002716
Autor:
Nina Hutri-Kähönen, Merja Kallio, Terho Lehtimäki, Markus Juonala, Jarkko S. Heiskanen, Jorma Viikari, Jussi Hernesniemi, Eero Jokinen, Mika Kähönen, Tomi Laitinen, Olli T. Raitakari, Päivi Tossavainen, Saku Ruohonen, Jaakko Nevalainen
Publikováno v:
Annals of Medicine
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Background Increased left ventricular mass (LVM) predicts cardiovascular events and mortality. The objective of this study was to determine whether early-life exposures to body mass index (BMI) and systolic blood pressure (SPB) affects the left ventr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7753e9fe0a86e120ba0ff43673630a5
http://europepmc.org/articles/PMC7877918
http://europepmc.org/articles/PMC7877918
Autor:
Tuija Tammelin, Kaisla Komulainen, Laura Pulkki-Råback, Olli T. Raitakari, Markus Juonala, Katja Pahkala, Saku Ruohonen, Mika Kähönen, Tomi T. Laitinen, Marko Elovainio, Murray A. Mittleman, Markus Jokela, Liisa Keltikangas-Järvinen
Publikováno v:
American Journal of Preventive Medicine. 57:e195-e202
Introduction: This study used causal mediation analysis to assess the life-course associations of a favorable childhood psychosocial environment with left ventricular mass and diastolic function in adulthood and the extent to which adult health behav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d35effff66170e4ac591da04708ca6
https://doi.org/10.1016/j.amepre.2019.08.018
https://doi.org/10.1016/j.amepre.2019.08.018