Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sakthivignesh Ponandai-srinivasan"'
Autor:
Thomas E. Bartlett, Iona Evans, Allison Jones, James E. Barrett, Shaun Haran, Daniel Reisel, Kiriaki Papaikonomou, Louise Jones, Chiara Herzog, Nora Pashayan, Bruno M. Simões, Robert B. Clarke, D. Gareth Evans, Talayeh S. Ghezelayagh, Sakthivignesh Ponandai-Srinivasan, Nageswara R. Boggavarapu, Parameswaran G. Lalitkumar, Sacha J. Howell, Rosa Ana Risques, Angelique Flöter Rådestad, Louis Dubeau, Kristina Gemzell-Danielsson, Martin Widschwendter
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-18 (2022)
Abstract Background Breast cancer is a leading cause of death in premenopausal women. Progesterone drives expansion of luminal progenitor cells, leading to the development of poor-prognostic breast cancers. However, it is not known if antagonising pr
Externí odkaz:
https://doaj.org/article/3c4f667ea36343489d62c2a38deb1ee7
Autor:
Yiqun Tang, Sakthivignesh Ponandai-srinivasan, Caroline Frisendahl, Johanna K. Andersson, Dora Pavone, Elizabeth A. Stewart, Parameswaran Grace Luther Lalitkumar, Eberhard Korsching, Nageswara Rao Bogavarappu, Kristina Gemzell-Danielsson
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
ObjectiveBromocriptine treatment has been shown to reduce menstrual bleeding and pain in women with adenomyosis in a pilot clinical trial. The underlying mechanism contributing to the treatment effect is however unknown. The purpose of this study was
Externí odkaz:
https://doaj.org/article/0f679915a00e4bccac00cb5d833d71b2
Autor:
Thomas E. Bartlett, Iona Evans, Allison Jones, James E. Barrett, Shaun Haran, Daniel Reisel, Kiriaki Papaikonomou, Louise Jones, Chiara Herzog, Nora Pashayan, Bruno M. Simões, Robert B. Clarke, D. Gareth Evans, Talayeh S. Ghezelayagh, Sakthivignesh Ponandai-Srinivasan, Nageswara R. Boggavarapu, Parameswaran G. Lalitkumar, Sacha J. Howell, Rosa Ana Risques, Angelique Flöter Rådestad, Louis Dubeau, Kristina Gemzell-Danielsson, Martin Widschwendter
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/e33dc40c9a65449694cb3d0e780845d4
Autor:
Merli Saare, Pablo Angel García-Uribe, Andres Salumets, Jasmin Rettkowski, P.G.L. Lalitkumar, Caroline Frisendahl, Sakthivignesh Ponandai-Srinivasan, Aditi Iyengar, Christoph Riethmüller, Nageswara Rao Boggavarapu, Sophia Ehrström, Martin Götte, Kristina Gemzell-Danielsson
Publikováno v:
Human Reproduction
STUDY QUESTION What is the physiological role of transforming growth factor-beta (TGF-β1) and syndecans (SDC1, SDC4) in endometriotic cells in women with endometriosis? SUMMARY ANSWER We observed an abnormal, pro-invasive phenotype in a subgroup of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab235f8cdaf6212b4e3a564bc19ec849
https://doi.org/10.1093/humrep/deaa164
https://doi.org/10.1093/humrep/deaa164
Autor:
Laura Garcia, Suby Jo Varghese, Sakthivignesh Ponandai-Srinivasan, P.G.L. Lalitkumar, Angelique Flöter Rådestad, Joseph W. Carlson, Kristina Gemzell-Danielsson
Publikováno v:
Acta Obstetricia et Gynecologica Scandinavica. 98:250-261
Introduction Women with hereditary mutation in breast cancer-associated genes (BRCA1-/2- ) have a higher lifetime risk of developing ovarian cancer. Here, we aimed to investigate the effect of mifepristone, a selective progesterone receptor modulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf7a560e0ba0dbde5345a9f3baa62465
https://doi.org/10.1111/aogs.13485
https://doi.org/10.1111/aogs.13485
Autor:
S Ehström, Merli Saare, Kristina Gemzell-Danielsson, Sakthivignesh Ponandai-Srinivasan, NR Boggavarapu, PG Lalitkumar, M Götte, Andres Salumets, PA Garcìa-Uribe
Publikováno v:
Regional plenary.
Objectives Transforming growth factor-beta (TGF-β) is abundantly expressed in peritoneal fluid and endometrioma of women with endometriosis. Similarly, transmembrane proteoglycans of the Syndecan family (SDC), act as co-receptors for growth signalli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81eb305828654939081098c719eff9ad
https://doi.org/10.1136/ijgc-2019-igcs.58
https://doi.org/10.1136/ijgc-2019-igcs.58
Autor:
Sakthivignesh, Ponandai-Srinivasan, Parameswaran G, Lalitkumar, Laura, Garcia, Suby Jo, Varghese, Joseph W, Carlson, Kristina, Gemzell-Danielsson, Angelique, Floter Radestad
Publikováno v:
Acta obstetricia et gynecologica Scandinavica. 98(2)
Women with hereditary mutation in breast cancer-associated genes (BRCAOvarian BRCAThe dose response with mifepristone treatment suggested an optimal effect with 10 μm mifepristone, exhibiting90% viability and significantly reducing growth signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c76f32e41a21d9e8d440194125401b91
https://pubmed.ncbi.nlm.nih.gov/30325501
https://pubmed.ncbi.nlm.nih.gov/30325501
Autor:
Kertu Liis Krigul, Sakthivignesh Ponandai-Srinivasan, Andres Salumets, Parameswaran Grace Lalit Kumar, Maire Peters, Nilufer Rahmioglu, Merli Saare, Krina T. Zondervan, Triin Laisk-Podar
Publikováno v:
Biology of Reproduction
Alterations in the DNA methylation pattern of endometriotic lesions and endometrium of endometriosis patients have been proposed as one potential factor accompanying the endometriosis development. Although many differentially methylated genes have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcba3c1e18a72c60491c03101157ab43
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
Sakthivignesh Ponandai-Srinivasan, Merli Saare, Andres Salumets, Halima A Hassan, K.L. Andersson, Kristina Gemzell-Danielsson, Monica Nistér, P.G.L. Lalitkumar, Maire Peters, Suby Jo Varghese
Publikováno v:
Human Reproduction
STUDY QUESTION Is there molecular evidence for a link between endometriosis and endometriosis-associated ovarian cancers (EAOC)? STUDY ANSWER We identified aberrant gene expression signatures associated with malignant transformation in a small subgro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba5b0ff2676dc9b11d38adb6e0720b6
https://pubmed.ncbi.nlm.nih.gov/30020448
https://pubmed.ncbi.nlm.nih.gov/30020448