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Akademický článek

Polar lipids modify Alzheimer’s Disease pathology by reducing astrocyte pro-inflammatory signaling through platelet-activating factor receptor (PTAFR) modulation

Autor: Sakshi Hans, Janelle E. Stanton, Ann Katrin Sauer, Katie Shiels, Sushanta Kumar Saha, Ronan Lordan, Alexandros Tsoupras, Ioannis Zabetakis, Andreas M. Grabrucker

Publikováno v: Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-15 (2024)

Abstract Background Pro-inflammatory processes triggered by the accumulation of extracellular amyloid beta (Aβ) peptides are a well-described pathology in Alzheimer's disease (AD). Activated astrocytes surrounding Aβ plaques contribute to inflammat

Externí odkaz: https://doaj.org/article/3a74b145ab744594a7c353d4a6830522

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Akademický článek

Oil from Mullet Roe Byproducts: Effect of Oil Extraction Method on Human Erythrocytes and Platelets

Autor: Ioannis Tsamesidis, Paraskevi Tzika, Despoina Georgiou, Aggelos Charisis, Sakshi Hans, Ronan Lordan, Ioannis Zabetakis, Eleni P. Kalogianni

Publikováno v: Foods, Vol 13, Iss 1, p 79 (2023)

Background: The valorization of byproducts to obtain high nutritional value foods is of utmost importance for our planet where the population is booming. Among these products are oils rich in ω-3 fatty acids produced from fishery byproducts. Recentl

Externí odkaz: https://doaj.org/article/6eeb3f06f85541d0941451db14a0be4b

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Akademický článek

The Ex Vivo and In Vitro Antithrombotic Properties of Fermented Irish Ovine Yogurt Drink

Autor: Sakshi Hans, Harishkumar Rajendran, Katie Shiels, Sushanta Kumar Saha, Alexandros Tsoupras, Ronan Lordan, Ioannis Zabetakis

Publikováno v: Biology and Life Sciences Forum, Vol 26, Iss 1, p 91 (2023)

Platelet function is closely linked to cardiovascular health. Functional foods such as yogurt and oily fish are enriched in bioactive polar lipids, which can reduce platelet activation and the incidence of cardiovascular disease. This pilot project i

Externí odkaz: https://doaj.org/article/4a101161f18e42b48d2091db5ae6ff32

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Akademický článek

The Role of Dietary Lipids in Cognitive Health: Implications for Neurodegenerative Disease

Autor: Sakshi Hans, Alexandra Karadimou, John J. E. Mulvihill, Andreas M. Grabrucker, Ioannis Zabetakis

Publikováno v: Biomedicines, Vol 10, Iss 12, p 3250 (2022)

Neurodegenerative diseases are a group of disorders characterised by progressive loss of brain function. The most common of these is Alzheimer’s disease, a form of dementia. Intake of macro- and micro-nutrients impacts brain function, including mem

Externí odkaz: https://doaj.org/article/5d31eef1ff9549c8b491fb2b54bc7fda

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