Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sakina Zaïdi"'
Autor:
Yaw Asante, Katharina Benischke, Issra Osman, Quy A. Ngo, Jakob Wurth, Dominik Laubscher, Hyunmin Kim, Bhavatharini Udhayakumar, Md Imdadul H. Khan, Diana H. Chin, Jadon Porch, Maharshi Chakraborty, Richard Sallari, Olivier Delattre, Sakina Zaidi, Sarah Morice, Didier Surdez, Sara G. Danielli, Beat W. Schäfer, Berkley E. Gryder, Marco Wachtel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Activation of oncogenic gene expression from long-range enhancers is initiated by the assembly of DNA-binding transcription factors (TF), leading to recruitment of co-activators such as CBP/p300 to modify the local genomic context and facili
Externí odkaz:
https://doaj.org/article/8b11c89f44b84a3f89f0cbe46cf89665
Autor:
Audrey Astori, Gabriel Matherat, Isabelle Munoz, Emilie-Fleur Gautier, Didier Surdez, Yaël Zermati, Frédérique Verdier, Sakina Zaidi, Vincent Feuillet, Amir Kadi, Evelyne Lauret, Olivier Delattre, Carine Lefèvre, Michaela Fontenay, Evelyne Ségal-Bendirdjian, Isabelle Dusanter-Fourt, Didier Bouscary, Olivier Hermine, Patrick Mayeux, Frédéric Pendino
Publikováno v:
Haematologica, Vol 107, Iss 1 (2020)
The gene CXXC5, encoding a retinoid-inducible nuclear factor (RINF), is located within a region at 5q31.2 commonly deleted in myelodysplastic syndrome and adult acute myeloid leukemia. RINF may act as an epigenetic regulator and has been proposed as
Externí odkaz:
https://doaj.org/article/2dd159ffad414e7599e33471931871d4
Autor:
Cécile Thirant, Agathe Peltier, Simon Durand, Amira Kramdi, Caroline Louis-Brennetot, Cécile Pierre-Eugène, Margot Gautier, Ana Costa, Amandine Grelier, Sakina Zaïdi, Nadège Gruel, Irène Jimenez, Eve Lapouble, Gaëlle Pierron, Déborah Sitbon, Hervé J. Brisse, Arnaud Gauthier, Paul Fréneaux, Sandrine Grossetête, Laura G. Baudrin, Virginie Raynal, Sylvain Baulande, Angela Bellini, Jaydutt Bhalshankar, Angel M. Carcaboso, Birgit Geoerger, Hermann Rohrer, Didier Surdez, Valentina Boeva, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Noradrenergic and mesenchymal identities have been characterized in neuroblastoma cell lines according to their epigenetic landscapes and core regulatory circuitries. However, their relationship and relative contribution in patient tumors re
Externí odkaz:
https://doaj.org/article/04ed19984e944c97b2d0494d3dadfd31
Autor:
Marie-Ming Aynaud, Olivier Mirabeau, Nadege Gruel, Sandrine Grossetête, Valentina Boeva, Simon Durand, Didier Surdez, Olivier Saulnier, Sakina Zaïdi, Svetlana Gribkova, Aziz Fouché, Ulykbek Kairov, Virginie Raynal, Franck Tirode, Thomas G.P. Grünewald, Mylene Bohec, Sylvain Baulande, Isabelle Janoueix-Lerosey, Jean-Philippe Vert, Emmanuel Barillot, Olivier Delattre, Andrei Zinovyev
Publikováno v:
Cell Reports, Vol 30, Iss 6, Pp 1767-1779.e6 (2020)
Summary: EWSR1-FLI1, the chimeric oncogene specific for Ewing sarcoma (EwS), induces a cascade of signaling events leading to cell transformation. However, it remains elusive how genetically homogeneous EwS cells can drive the heterogeneity of transc
Externí odkaz:
https://doaj.org/article/17c804ad436946fd839b98dcb2674815
Publikováno v:
In Heliyon July 2023 9(7)
Autor:
Erika Brunet, Didier Surdez, Olivier Delattre, Thomas G.P. Grünewald, Maria Jasin, Mark Tomishima, Sophie Kaltenbach, Lucile Couronné, Isabelle Janoueix-Lerosey, Cécile Pierre-Eugène, Carine Giovannangeli, Anne De Cian, Benjamin Renouf, Patrick Revy, Sakina Zaïdi, Loelia Babin, Maxime Heintzé, Sandrine Grossetête, Anna Sole
Ewing sarcoma is characterized by pathognomonic translocations, most frequently fusing EWSR1 with FLI1. An estimated 30% of Ewing sarcoma tumors also display genetic alterations in STAG2, TP53, or CDKN2A (SPC). Numerous attempts to develop relevant E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23b462046e012718bca74554bcfef791
https://doi.org/10.1158/0008-5472.c.6513129.v1
https://doi.org/10.1158/0008-5472.c.6513129.v1
Autor:
Erika Brunet, Didier Surdez, Olivier Delattre, Thomas G.P. Grünewald, Maria Jasin, Mark Tomishima, Sophie Kaltenbach, Lucile Couronné, Isabelle Janoueix-Lerosey, Cécile Pierre-Eugène, Carine Giovannangeli, Anne De Cian, Benjamin Renouf, Patrick Revy, Sakina Zaïdi, Loelia Babin, Maxime Heintzé, Sandrine Grossetête, Anna Sole
SupReferences+SupMAt&Met+Suptables+SupFig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8a17d1c9f12fd5960c967e79eef0e6
https://doi.org/10.1158/0008-5472.22428768
https://doi.org/10.1158/0008-5472.22428768
Autor:
Matthieu Ribon, Lorenzo Schiaffino, Christian S Lobsiger, Michel Mallat, Pierre de la Grange, Félix Berriat, Danielle Seilhean, Delphine Bohl, Charlène Iltis, Séverine Boillée, Aude Chiot, Sakina Zaïdi, Ariane Jolly, Stéphanie Millecamps
Publikováno v:
Nature Neuroscience
Nature Neuroscience, 2020, 23 (11), pp.1339-1351. ⟨10.1038/s41593-020-00718-z⟩
Nature Neuroscience, 2020, 23 (11), pp.1339-1351. ⟨10.1038/s41593-020-00718-z⟩
International audience; Microglia and peripheral macrophages have both been implicated in amyotrophic lateral sclerosis (ALS), although their respective roles have yet to be determined. We now show that macrophages along peripheral motor neuron axons
Autor:
Olivier, Saulnier, Katia, Guedri-Idjouadiene, Marie-Ming, Aynaud, Alina, Chakraborty, Jonathan, Bruyr, Joséphine, Pineau, Tina, O'Grady, Olivier, Mirabeau, Sandrine, Grossetête, Bartimée, Galvan, Margaux, Claes, Zahra, Al Oula Hassoun, Benjamin, Sadacca, Karine, Laud, Sakina, Zaïdi, Didier, Surdez, Sylvain, Baulande, Xavier, Rambout, Franck, Tirode, Martin, Dutertre, Olivier, Delattre, Franck, Dequiedt
Publikováno v:
Nucleic Acids Research
ERG family proteins (ERG, FLI1 and FEV) are a subfamily of ETS transcription factors with key roles in physiology and development. In Ewing sarcoma, the oncogenic fusion protein EWS-FLI1 regulates both transcription and alternative splicing of pre-me
Autor:
Aude, Chiot, Sakina, Zaïdi, Charlène, Iltis, Matthieu, Ribon, Félix, Berriat, Lorenzo, Schiaffino, Ariane, Jolly, Pierre, de la Grange, Michel, Mallat, Delphine, Bohl, Stéphanie, Millecamps, Danielle, Seilhean, Christian S, Lobsiger, Séverine, Boillée
Publikováno v:
Nature neuroscience. 23(11)
Microglia and peripheral macrophages have both been implicated in amyotrophic lateral sclerosis (ALS), although their respective roles have yet to be determined. We now show that macrophages along peripheral motor neuron axons in mouse models and pat