Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sakina Orkhis"'
Autor:
Madhuparna Nandi, Mitterrand Muamba Moyo, Sakina Orkhis, Jeanne Masunga Faida Mobulakani, Marc-André Limoges, Fjolla Rexhepi, Marian Mayhue, Anny Armas Cayarga, Gisela Cofino Marrero, Subburaj Ilangumaran, Alfredo Menendez, Sheela Ramanathan
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Interleukin-15, produced by hematopoietic and parenchymal cells, maintains immune cell homeostasis and facilitates activation of lymphoid and myeloid cell subsets. IL-15 interacts with the ligand-binding receptor chain IL-15Rα during biosynthesis, a
Externí odkaz:
https://doaj.org/article/9d34f11efbbe4603ac7f330ed52290e6
Autor:
Sheela Ramanathan, Yi-Guang Chen, Alfredo Menendez, Gregory Lacraz, Farnaz Ghobadi, Yuneivy Cepero-Donates, Marian Mayhue, Subburaj Ilangumaran, Sakina Orkhis, Volatiana Rakotoarivelo, Marek Rola-Pleszczynski
Publikováno v:
Cytokine, 82, 102. Academic Press Inc.
Cytokine, 82, 102
Cytokine, 82, 102
Interleukin-15 (IL-15) is essential for the homeostasis of lymphoid cells particularly memory CD8(+) T cells and NK cells. These cells are abundant in the liver, and are implicated in obesity-associated pathogenic processes. Here we characterized obe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a6d04aea1c5ae7b025ce6e1747342b
https://dspace.library.uu.nl/handle/1874/360160
https://dspace.library.uu.nl/handle/1874/360160
Publikováno v:
Cytokine. 85
IL-21 promotes autoimmune type-1 diabetes (T1D) in NOD mice by facilitating CD4(+) T cell help to CD8(+) T cells. IL-21 also enables autoreactive CD8(+) T cells to respond to weak TCR ligands and induce T1D. Here, we assessed whether IL-21 is essenti