Výsledky vyhledávání - "Sakina Mhaouty"

Akademický článek

Lithium and endocrine disruption: A concern for human health?

Autor: Nicolas Chevalier, Pauline Guillou, Catherine Viguié, Jean-Baptiste Fini, Laurent M. Sachs, Cécile Michel-Caillet, Sakina Mhaouty-Kodja

Publikováno v: Environment International, Vol 190, Iss , Pp 108861- (2024)

Lithium is a key medication for the treatment of psychiatric disorders and is also used in various industrial applications (including battery production and recycling). Here, we review published data on the endocrine-disrupting potential of lithium,

Externí odkaz: https://doaj.org/article/02c0c732896e4811a0462e7a28e7218d

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Akademický článek

Reproductive function and behaviors: an update on the role of neural estrogen receptors alpha and beta

Autor: Thomas Torres, Nolwenn Adam, Sakina Mhaouty-Kodja, Lydie Naulé

Publikováno v: Frontiers in Endocrinology, Vol 15 (2024)

Infertility is becoming a major public health problem, with increasing frequency due to medical, environmental and societal causes. The increasingly late age of childbearing, growing exposure to endocrine disruptors and other reprotoxic products, and

Externí odkaz: https://doaj.org/article/8d206a03f2cb49b592966af2e1827ce6

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Akademický článek

Deletion of neural estrogen receptor alpha induces sex differential effects on reproductive behavior in mice

Autor: Anne-Charlotte Trouillet, Suzanne Ducroq, Lydie Naulé, Daphné Capela, Caroline Parmentier, Sally Radovick, Hélène Hardin-Pouzet, Sakina Mhaouty-Kodja

Publikováno v: Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)

Neural deletion of the estrogen receptor, ERα, inhibits sexual behavior in female mice, but only has moderately effect in male mice. These results contrast with previous studies using global ERα knockouts, which found that ERα is mandatory for rep

Externí odkaz: https://doaj.org/article/40a06df77732447d91c0df9fcd9d3e29

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Akademický článek

Effects of neural estrogen receptor beta deletion on social and mood-related behaviors and underlying mechanisms in male mice

Autor: Carlos Dombret, Lydie Naulé, Anne-Charlotte Trouillet, Caroline Parmentier, Hélène Hardin-Pouzet, Sakina Mhaouty-Kodja

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)

Abstract Estradiol derived from neural aromatization of testosterone plays a key role in the organization and activation of neural structures underlying male behaviors. This study evaluated the contribution of the estrogen receptor (ER) β in estradi

Externí odkaz: https://doaj.org/article/13c62b1ac1494c4b928cf5b5ac50dba2

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Akademický článek

Roadbumps at the Crossroads of Integrating Behavioral and In Vitro Approaches for Neurotoxicity Assessment

Autor: G. Jean Harry, Sandra McBride, Shannah K. Witchey, Sakina Mhaouty-Kodja, Alain Trembleau, Matthew Bridge, Anna Bencsik

Publikováno v: Frontiers in Toxicology, Vol 4 (2022)

With the appreciation that behavior represents the integration and complexity of the nervous system, neurobehavioral phenotyping and assessment has seen a renaissance over the last couple of decades, resulting in a robust database on rodent performan

Externí odkaz: https://doaj.org/article/28cfb7f2d7684740b3264d52e4501e01

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Akademický článek

Perinatal Exposure to Methoxychlor Affects Reproductive Function and Sexual Behavior in Mice

Autor: Mariangela Martini, Pascal Froment, Isabelle Franceschini, Delphine Pillon, Edith Guibert, Claude Cahier, Sakina Mhaouty-Kodja, Matthieu Keller

Publikováno v: Frontiers in Endocrinology, Vol 11 (2020)

Numerous chemicals derived from human activity are now disseminated in the environment where their exert estrogenic endocrine disrupting effects, and therefore represent major health concerns. The present study explored whether Methoxychlor (MXC), an

Externí odkaz: https://doaj.org/article/11cefa61d731468bb5fa541a6b8627fe

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Akademický článek

Neural Androgen Receptor Deletion Impairs the Temporal Processing of Objects and Hippocampal CA1-Dependent Mechanisms.

Autor: Marie Picot, Jean-Marie Billard, Carlos Dombret, Christelle Albac, Nida Karameh, Stéphanie Daumas, Hélène Hardin-Pouzet, Sakina Mhaouty-Kodja

Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0148328 (2016)

We studied the role of testosterone, mediated by the androgen receptor (AR), in modulating temporal order memory for visual objects. For this purpose, we used male mice lacking AR specifically in the nervous system. Control and mutant males were gona

Externí odkaz: https://doaj.org/article/bc26a2aabf214b059cf623b2ce71d509

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