Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Saki Omote"'
Autor:
Yuki Asai, Hiroki Arihara, Saki Omote, Ena Tanio, Saena Yamashita, Takashi Higuchi, Ei Hashimoto, Momoko Yamada, Hinako Tsuji, Yoshihiro Kondo, Makoto Hayashi, Yoshiaki Yamamoto
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract Background Polypharmacy, defined as the concurrent use of over six drugs, is common in the treatment of heart failure (HF); however, unpredictable drug interactions with bepridil may occur. In this study, we have elucidated the influence of
Externí odkaz:
https://doaj.org/article/8e3faa6f94db45fcbd442b0f63b17647
Autor:
Yuki Asai, Takumi Tashiro, Yoshihiro Kondo, Makoto Hayashi, Hiroki Arihara, Saki Omote, Ena Tanio, Saena Yamashita, Takashi Higuchi, Ei Hashimoto, Momoko Yamada, Hinako Tsuji, Yuji Hayakawa, Ryohei Suzuki, Hiroya Muro, Yoshiaki Yamamoto
Publikováno v:
Biological and Pharmaceutical Bulletin. 46:614-620
Publikováno v:
Journal of Pharmaceutical Sciences. 106:2899-2903
Crizotinib, a tyrosine kinase inhibitor, exhibits some cases of an increase in serum creatinine levels. Creatinine is excreted by not only glomerular filtration but also active secretion by organic cation transporters such as organic cation transport
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Creatinine is actively secreted across tubular epithelial cells via organic cation transporter 2 (OCT2) and multidrug and toxin extrusion 1 (MATE1). We previously showed that the tyrosine kinase inhibitor (TKI) crizotinib inhibits OCT2-mediated trans