Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Saki Nishi"'
Autor:
Saki Nishikawa, Gaku Sato, Sakura Takada, Shunshi Kohyama, Gen Honda, Miho Yanagisawa, Yutaka Hori, Nobuhide Doi, Natsuhiko Yoshinaga, Kei Fujiwara
Publikováno v:
Advanced Science, Vol 11, Iss 6, Pp n/a-n/a (2024)
Abstract Cells are small, closed spaces filled with various types of macromolecules. Although it is shown that the characteristics of biochemical reactions in vitro are quite different from those in living cells, the role of the co‐existence of var
Externí odkaz:
https://doaj.org/article/f1fe95f794bb4244bc6b0b8052d83b5d
Autor:
Peter A. Savage, Nicholas D. Socci, Saki Nishi, Daniel S. Leventhal, Victoria Lee, Sven Malchow
Publikováno v:
Immunity. 44:1102-1113
The promiscuous expression of tissue-restricted antigens in the thymus, driven in part by autoimmune regulator (Aire), is critical for the protection of peripheral tissues from autoimmune attack. Aire-dependent processes are thought to promote both c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a6e7ca3cddff7e0c378a46bae60287
https://doi.org/10.1016/j.immuni.2016.02.009
https://doi.org/10.1016/j.immuni.2016.02.009
Autor:
Haochu Huang, Douglas E. Kline, Peter A. Savage, Julian M. Berger, Nicholas D. Socci, Donald J. Vander Griend, Sven Malchow, Saki Nishi, Daniel S. Leventhal, Victoria Lee, Dana C. Gilmore, Justin Kline
Publikováno v:
Immunity. 44:847-859
Although antigen recognition mediated by the T cell receptor (TCR) influences many facets of Foxp3(+) regulatory T (Treg) cell biology, including development and function, the cell types that present antigen to Treg cells in vivo remain largely undef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09fa976a17f6da7f27400b8b0c89b9ea
https://doi.org/10.1016/j.immuni.2016.01.025
https://doi.org/10.1016/j.immuni.2016.01.025
Autor:
Dominick Fosco, Justin Kline, Peter A. Savage, Douglas E. Kline, Saki Nishi, Xiufen Chen, Liping Meng
Publikováno v:
European Journal of Immunology. 44:2603-2616
Treg cells and the programed death-1/programed death ligand-1 (PD-1/PD-L1) pathway are both critical for maintaining peripheral tolerance to self-Ags. A significant subset of Treg cells constitutively expresses PD-1, which prompted an investigation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54e4ba6d5a0495068928686115545a20
https://doi.org/10.1002/eji.201344423
https://doi.org/10.1002/eji.201344423
Autor:
Xiufen, Chen, Dominick, Fosco, Douglas E, Kline, Liping, Meng, Saki, Nishi, Peter A, Savage, Justin, Kline
Publikováno v:
European journal of immunology. 44(9)
Regulatory T (Treg) cells and the programmed death-1/programmed death ligand-1 (PD-1/PD-L1) pathway are both critical for maintaining peripheral tolerance to self antigens. A significant subset of Treg cells constitutively expresses PD-1, which promp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fba96eabf6d11d63e3c5252be2c09d05
https://pubmed.ncbi.nlm.nih.gov/24975127
https://pubmed.ncbi.nlm.nih.gov/24975127
Publikováno v:
Surgical Case Reports, Vol 7, Iss 1, Pp 1-4 (2021)
Abstract Background Cyclic neutropenia is a disease that causes a neutropenic decrease in peripheral blood in a cycle of about 21 days. It is a rare hereditary disorder with an estimated incidence of 0.5–1 cases per million population. The absolute
Externí odkaz:
https://doaj.org/article/9a1950a2a7014c4e9d73cbf3eb5aaf1e
Publikováno v:
The Journal of Immunology. 190:111.15-111.15
The enrichment of Foxp3+ regulatory T cells (Tregs) constitutes a central mechanism of immune regulation, but has also been associated with poor patient prognosis in a variety of human cancers. Previous studies have suggested that Treg development, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::456cd679b16ebec0a43d97de5aaa810d
https://doi.org/10.4049/jimmunol.190.supp.111.15
https://doi.org/10.4049/jimmunol.190.supp.111.15
Publikováno v:
The Journal of Immunology. 190:170.52-170.52
For some human cancers, elevated densities of Foxp3+ regulatory T cells (Tregs) in the tumor tissue correlate with poor prognosis, suggesting that Tregs may play a functional role in cancer progression. Despite considerable interest in the modulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4313bd5b5b189756d5964011d1263c33
https://doi.org/10.4049/jimmunol.190.supp.170.52
https://doi.org/10.4049/jimmunol.190.supp.170.52
Publikováno v:
The Journal of Immunology. 190:50.35-50.35
While the transcription factor Autoimmune Regulator (AIRE) has been shown to play a critical role in establishing immune tolerance through the negative selection of T cells reactive to peripheral antigens, the role of AIRE in the thymic development o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7546bed2e07e689272276b2cf590449b
https://doi.org/10.4049/jimmunol.190.supp.50.35
https://doi.org/10.4049/jimmunol.190.supp.50.35
Autor:
Motoki Isawa, Akiko Karakawa, Nobuhiro Sakai, Saki Nishina, Miku Kuritani, Masahiro Chatani, Takako Negishi-Koga, Masashi Sato, Mitsuko Inoue, Yukie Shimada, Masamichi Takami
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract The anti-bone resorptive drugs denosumab, an anti-human-RANKL antibody, and zoledronic acid (ZOL), a nitrogen-containing bisphosphonate, have recently been applied for treatment of pediatric patients with bone diseases, though details regard
Externí odkaz:
https://doaj.org/article/b70533e1eb9249e487693f5b7a41ef4c