Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Saki, Ariizumi"'
Autor:
Hiroyuki Koide, Anna Okishima, Yu Hoshino, Yuri Kamon, Keiichi Yoshimatsu, Kazuhiro Saito, Ikumi Yamauchi, Saki Ariizumi, Yuqi Zhou, Ting-Hui Xiao, Keisuke Goda, Naoto Oku, Tomohiro Asai, Kenneth J. Shea
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Sepsis caused by the release of inflammatory mediators into the blood is a life threatening disease. Here, the authors report on the development of hydrogel nanoparticles for the capture and neutralisation of histones, major inflammatory mediators, a
Externí odkaz:
https://doaj.org/article/eb612ef6ea67468793984170be09b6f2
Autor:
Kenneth J. Shea, Hiroyuki Koide, Saki Ariizumi, Tomohiro Asai, Keiichi Yoshimatsu, Yu Hoshino, Yuri Kamon, Yuqi Zhou, Ikumi Yamauchi, Naoto Oku, Anna Okishima, Kazuhiro Saito, Keisuke Goda, Ting Hui Xiao
Publikováno v:
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Sepsis is a life-threatening condition caused by the extreme release of inflammatory mediators into the blood in response to infection (e.g., bacterial infection, COVID-19), resulting in the dysfunction of multiple organs. Currently, there is no dire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b15baf338ab028849426107cd7f214c
https://escholarship.org/uc/item/152483pj
https://escholarship.org/uc/item/152483pj
Autor:
Tatsuya Fukuta, Anna Okishim, Naoto Oku, Hiroki Tsuchida, Hidenori Ando, Keiichi Yoshimatsu, Yu Hoshino, Takehisa Dewa, Kenneth J. Shea, Hiroyuki Koide, Chiaki Kiyokawa, Tomohiro Asai, Saki Ariizumi, Masahiko Nakamoto
Publikováno v:
Biomacromolecules. 20:3648-3657
The affinity of a synthetic polymer nanoparticle (NP) to a target biomacromolecule is determined by the association and dissociation rate constants (kon, koff) of the interaction. The individual rates and their sensitivity to local environmental infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::533fc9330cb6027afc027b6cf41d1df8
https://doi.org/10.1021/acs.biomac.9b00611
https://doi.org/10.1021/acs.biomac.9b00611
Autor:
Hiroyuki Koide, Yu Hoshino, Saki Ariizumi, Anna Okishima, Hiroki Tsuchida, Chiaki Kiyokawa, Masahiko Nakamoto, Tomohiro Asai, Naoto Oku
Publikováno v:
Journal of Controlled Release. 268:335-342
Many of macromolecular toxins induce cell death by directly interacting with cells or induction of inflammatory cytokines. Abiotic polymer ligands (PLs) composed of functional monomers are able to bind and neutralize toxins in vivo and are of great i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58776405d267c128b28d644d317d54a9
https://doi.org/10.1016/j.jconrel.2017.10.028
https://doi.org/10.1016/j.jconrel.2017.10.028
Autor:
Yoshiko Miura, Saki Ariizumi, Yuri Nishimura, Naoto Oku, Kenneth J. Shea, Ai Okajima, Adam Weisman, Yudai Narita, Yusuke Yonamine, Hiroyuki Koide, Shih Hui Lee, Keiichi Yoshimatsu, Yu Hoshino
Publikováno v:
Nature Chemistry. 9:715-722
Protein affinity reagents are widely used in basic research, diagnostics and separations and for clinical applications, the most common of which are antibodies. However, they often suffer from high cost, and difficulties in their development, product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb8c93e3c1789eef5d009ef6f1e69205
https://doi.org/10.1038/nchem.2749
https://doi.org/10.1038/nchem.2749
Autor:
Yuichiro Maekawa, Saki Ariizumi, Masao Saotome, Kohei Hoshikawa, Takafumi Naito, Shunta Akutsu, Junichi Kawakami
Publikováno v:
Journal of Chromatography B. 1146:122121
Edoxaban is mainly enzymatically converted to a 4-carboxylic acid form (4CA-EDX) and an N-desmethyl form (ND-EDX) in humans. This study aimed to establish a simple liquid chromatography-tandem mass spectrometry method using core-shell octadecyl silic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4ff6619cb60a6f816f3754016f3795
http://hdl.handle.net/10271/00004154
http://hdl.handle.net/10271/00004154
Autor:
Naoto Oku, Yoshiko Miura, Keiichi Yoshimatsu, Hiroaki Kanazawa, Yu Hoshino, Yuri Nishimura, Yoshitaka Hamashima, Kenneth J. Shea, Tomohiro Asai, Saki Ariizumi, Hiroyuki Koide, Anna Okishima, Takafumi Ide, Hiromichi Egami
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 295
Protein affinity reagents (PARs), frequently antibodies, are essential tools for basic research, diagnostics, separations and for clinical applications. However, there is growing concern about the reproducibility, quality and cost of recombinant and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4891ccb0c9b0ce7713ecc17c88aa5260
https://pubmed.ncbi.nlm.nih.gov/30578808
https://pubmed.ncbi.nlm.nih.gov/30578808
Autor:
Takehisa Dewa, Naoto Oku, Saki Ariizumi, Masahiro Hashimoto, Tomohiro Asai, Hiroki Tsuchida, Ayaka Okamoto, Chiaki Kiyokawa, Hidenori Ando, Hiroyuki Koide
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 228
Small interfering RNA (siRNA) has the potential to be a candidate as a cure for intractable diseases. However, an appropriate vector is required for siRNA delivery because of the low transfection efficiency of siRNA without a vector and its easy degr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9cbd6d1eb5f655ddb89b6f86dc7c7d6
https://pubmed.ncbi.nlm.nih.gov/26826309
https://pubmed.ncbi.nlm.nih.gov/26826309
Autor:
Hiroyuki, Koide, Keiichi, Yoshimatsu, Yu, Hoshino, Shih-Hui, Lee, Ai, Okajima, Saki, Ariizumi, Yudai, Narita, Yusuke, Yonamine, Adam C, Weisman, Yuri, Nishimura, Naoto, Oku, Yoshiko, Miura, Kenneth J, Shea
Publikováno v:
Nature chemistry. 9(7)
Protein affinity reagents are widely used in basic research, diagnostics and separations and for clinical applications, the most common of which are antibodies. However, they often suffer from high cost, and difficulties in their development, product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da7c7c17d7f1b2eb09a1280bd89ae6e2
https://pubmed.ncbi.nlm.nih.gov/28644480
https://pubmed.ncbi.nlm.nih.gov/28644480
Autor:
Hiroyuki Koide, Tatsuya Fukuta, Anna Okishim, Saki Ariizumi, Chiaki Kiyokawa, Hiroki Tsuchida, Masahiko Nakamoto, Keiichi Yoshimatsu, Hidenori Ando, Takehisa Dewa, Tomohiro Asai, Naoto Oku, Yu Hoshino, Shea, Kenneth J.
Publikováno v:
Biomacromolecules; Oct2019, Vol. 20 Issue 10, p3648-3657, 10p