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Dihydroazolopyrimidines: Past, Present and Perspectives in Synthesis, Green Chemistry and Drug Discovery.

Autor: Desenko SM; Department of Organic and Bioorganic Chemistry, State Scientific Institution 'Institute for Single Crystals' NAS of Ukraine, Nauky ave. 60, Kharkiv, Ukraine, 61072., Gorobets MY; Department of Organic and Bioorganic Chemistry, State Scientific Institution 'Institute for Single Crystals' NAS of Ukraine, Nauky ave. 60, Kharkiv, Ukraine, 61072., Lipson VV; Department of Organic and Bioorganic Chemistry, State Scientific Institution 'Institute for Single Crystals' NAS of Ukraine, Nauky ave. 60, Kharkiv, Ukraine, 61072.; Faculty of Chemistry, V.N. Karazin Kharkiv National University, Svobody sq. 4, Kharkiv, Ukraine, 61022.; Department of Medicinal Chemistry, State Institution 'V. Ya. Danilevsky Institute for Endocrine Pathology Problems' NAMS of Ukraine, Alchevskikh St. 10, Kharkiv, Ukraine, 61002., Sakhno YI; Department of Organic and Bioorganic Chemistry, State Scientific Institution 'Institute for Single Crystals' NAS of Ukraine, Nauky ave. 60, Kharkiv, Ukraine, 61072., Chebanov VA; Department of Organic and Bioorganic Chemistry, State Scientific Institution 'Institute for Single Crystals' NAS of Ukraine, Nauky ave. 60, Kharkiv, Ukraine, 61072.; Faculty of Chemistry, V.N. Karazin Kharkiv National University, Svobody sq. 4, Kharkiv, Ukraine, 61022.

Publikováno v: Chemical record (New York, N.Y.) [Chem Rec] 2024 Feb; Vol. 24 (2), pp. e202300244. Date of Electronic Publication: 2023 Sep 05.

Aminoalkoxycarbonyloxymethyl Ether Prodrugs with a pH-Triggered Release Mechanism: A Case Study Improving the Solubility, Bioavailability, and Efficacy of Antimalarial 4(1 H )-Quinolones with Single Dose Cures.

Autor: Monastyrskyi A; Department of Chemistry, University of South Florida, CHE 205, 4202 E. Fowler Avenue, Tampa, Florida 33620, United States., Brockmeyer F; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, 102 Hurtig Hall, Boston, Massachusetts 02115, United States., LaCrue AN; Department of Global Health, College of Public Health, University of South Florida, 3720 Spectrum Blvd, Suite 304, Tampa, Florida 33612, United States., Zhao Y; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, 102 Hurtig Hall, Boston, Massachusetts 02115, United States., Maher SP; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Coverdell Center, Rm 370B, 500 DW Brooks Drive, Athens, Georgia 30602, United States., Maignan JR; Department of Chemistry, University of South Florida, CHE 205, 4202 E. Fowler Avenue, Tampa, Florida 33620, United States., Padin-Irizarry V; Department of Biology, Clayton State University, 2000 Clayton State Boulevard, Morrow, Georgia 30260, United States.; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Coverdell Center, Rm 370B, 500 DW Brooks Drive, Athens, Georgia 30602, United States., Sakhno YI; Department of Chemistry, University of South Florida, CHE 205, 4202 E. Fowler Avenue, Tampa, Florida 33620, United States., Parvatkar PT; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, 102 Hurtig Hall, Boston, Massachusetts 02115, United States., Asakawa AH; Department of Pharmaceutical Sciences, Northeastern University, 102 Hurtig Hall, 360 Huntington Avenue, Boston, Massachusetts 02115, United States., Huang L; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, 102 Hurtig Hall, Boston, Massachusetts 02115, United States., Casandra D; Department of Global Health, College of Public Health, University of South Florida, 3720 Spectrum Blvd, Suite 304, Tampa, Florida 33612, United States., Mashkouri S; Department of Global Health, College of Public Health, University of South Florida, 3720 Spectrum Blvd, Suite 304, Tampa, Florida 33612, United States., Kyle DE; Department of Global Health, College of Public Health, University of South Florida, 3720 Spectrum Blvd, Suite 304, Tampa, Florida 33612, United States.; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Coverdell Center, Rm 370B, 500 DW Brooks Drive, Athens, Georgia 30602, United States., Manetsch R; Department of Chemistry, University of South Florida, CHE 205, 4202 E. Fowler Avenue, Tampa, Florida 33620, United States.; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, 102 Hurtig Hall, Boston, Massachusetts 02115, United States.; Department of Pharmaceutical Sciences, Northeastern University, 102 Hurtig Hall, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2021 May 27; Vol. 64 (10), pp. 6581-6595. Date of Electronic Publication: 2021 May 12.

Doebner-type pyrazolopyridine carboxylic acids in an Ugi four-component reaction.

Autor: Murlykina MV; Division of Chemistry of Functional Materials, State Scientific Institution 'Institute for Single Crystals' of National Academy of Sciences of Ukraine, Nauky Ave., 60, 61072, Kharkiv, Ukraine.; Faculty of Chemistry, V. N. Karazin Kharkiv National University, Svobody sq., 4, 61077, Kharkiv, Ukraine.; Laboratory for Organic & Microwave-Assisted Chemistry (LOMAC), KU Leuven, Celestijnenlaan 200F, B-3001, Leuven, Belgium., Kolomiets OV; Division of Chemistry of Functional Materials, State Scientific Institution 'Institute for Single Crystals' of National Academy of Sciences of Ukraine, Nauky Ave., 60, 61072, Kharkiv, Ukraine.; Faculty of Chemistry, V. N. Karazin Kharkiv National University, Svobody sq., 4, 61077, Kharkiv, Ukraine., Kornet MM; Laboratory of Biotechnology of Physiologically Active Substances, Zaporizhzhia National University, Zhukovsky str., 66, Zaporizhzhya, Ukraine, 69600., Sakhno YI; Division of Chemistry of Functional Materials, State Scientific Institution 'Institute for Single Crystals' of National Academy of Sciences of Ukraine, Nauky Ave., 60, 61072, Kharkiv, Ukraine., Desenko SM; Division of Chemistry of Functional Materials, State Scientific Institution 'Institute for Single Crystals' of National Academy of Sciences of Ukraine, Nauky Ave., 60, 61072, Kharkiv, Ukraine.; Faculty of Chemistry, V. N. Karazin Kharkiv National University, Svobody sq., 4, 61077, Kharkiv, Ukraine., Dyakonenko VV; Division of Chemistry of Functional Materials, State Scientific Institution 'Institute for Single Crystals' of National Academy of Sciences of Ukraine, Nauky Ave., 60, 61072, Kharkiv, Ukraine., Shishkina SV; Division of Chemistry of Functional Materials, State Scientific Institution 'Institute for Single Crystals' of National Academy of Sciences of Ukraine, Nauky Ave., 60, 61072, Kharkiv, Ukraine.; Faculty of Chemistry, V. N. Karazin Kharkiv National University, Svobody sq., 4, 61077, Kharkiv, Ukraine., Brazhko OA; Laboratory of Biotechnology of Physiologically Active Substances, Zaporizhzhia National University, Zhukovsky str., 66, Zaporizhzhya, Ukraine, 69600., Musatov VI; Division of Chemistry of Functional Materials, State Scientific Institution 'Institute for Single Crystals' of National Academy of Sciences of Ukraine, Nauky Ave., 60, 61072, Kharkiv, Ukraine., Tsygankov AV; National Technical University 'Kharkiv Polytechnic Institute', Kyrpychova str., 2, 61002, Kharkiv, Ukraine., Van der Eycken EV; Laboratory for Organic & Microwave-Assisted Chemistry (LOMAC), KU Leuven, Celestijnenlaan 200F, B-3001, Leuven, Belgium.; Peoples' Friendship University of Russia, Miklukho-Maklya str., 6, 117198, Moscow, Russia., Chebanov VA; Division of Chemistry of Functional Materials, State Scientific Institution 'Institute for Single Crystals' of National Academy of Sciences of Ukraine, Nauky Ave., 60, 61072, Kharkiv, Ukraine.; Faculty of Chemistry, V. N. Karazin Kharkiv National University, Svobody sq., 4, 61077, Kharkiv, Ukraine.; Laboratory for Organic & Microwave-Assisted Chemistry (LOMAC), KU Leuven, Celestijnenlaan 200F, B-3001, Leuven, Belgium.

Publikováno v: Beilstein journal of organic chemistry [Beilstein J Org Chem] 2019 Jun 12; Vol. 15, pp. 1281-1288. Date of Electronic Publication: 2019 Jun 12 (Print Publication: 2019).

High regioselective ultrasonic-assisted synthesis of 2,7-diaryl-4,7-dihydropyrazolo[1,5-a]pyrimidine-5-carboxylic acids.

Autor: Chebanov VA; SSI, Institute for Single Crystals, NAS of Ukraine, Lenin Ave 60, Kharkiv 61001, Ukraine. chebanov@isc.kharkov.com, Sakhno YI, Desenko SM

Publikováno v: Ultrasonics sonochemistry [Ultrason Sonochem] 2012 May; Vol. 19 (3), pp. 707-9. Date of Electronic Publication: 2011 Aug 17.