Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Saket J. Thaker"'
Autor:
Saket J. Thaker, Prajakta P. Gandhe, Charuta J. Godbole, Shital R. Bendkhale, Nitin B. Mali, Urmila M. Thatte, Nithya J. Gogtay
Publikováno v:
Journal of Ayurveda and Integrative Medicine, Vol 8, Iss 1, Pp 37-41 (2017)
Background: Genetic polymorphisms in drug metabolizing enzymes (DMEs) impart distinct drug metabolizing capacity and a unique phenotype to an individual. Phenytoin has large inter-individual variability in metabolism due to polymorphisms in CYP2C9 an
Externí odkaz:
https://doaj.org/article/031a6e1331a14920b1291f112aea32d5
Autor:
Mansij Biswas, Shital R. Bendkhale, Siddharth P. Deshpande, Saket J. Thaker, Dwarkanath V. Kulkarni, Shobna J. Bhatia, Anjali G. Rajadhyaksha, Nithya J. Gogtay, Urmila M. Thatte
Publikováno v:
Indian Heart Journal, Vol 70, Iss , Pp S13-S19 (2018)
Objective: Genetic polymorphisms of CYP2C9 and VKORC1 play major role in pharmacokinetics and pharmacodynamics of warfarin, respectively. Purpose of our study was to assess the utility of pretesting patients for the above mutations in predicting tend
Externí odkaz:
https://doaj.org/article/742f466fe19d404a8fcb6280c551ceb4
Autor:
Brinal H Figer, Jeffrey Pradeep Raj, Saket J Thaker, Nithya Jaideep Gogtay, Urmila Mukund Thatte
Publikováno v:
Perspectives in Clinical Research, Vol 12, Iss 4, Pp 193-198 (2021)
Background: Abnormal laboratory values are a common reason for the exclusion of participants in clinical studies, increasing the recruitment time and cost during conduct. The use of sample-specific reference intervals (RIs) may help to address this i
Externí odkaz:
https://doaj.org/article/e19c36581146418fac9bb85953e9c79d
Autor:
Charuta J. Godbole, Urmila M Thatte, Milind Y Nadkar, Saket J. Thaker, Prafulla Kerkar, Nithya J Gogtay
Publikováno v:
Future Cardiology. 17:119-126
Background: The present case–control study evaluated the association of PON1 gene polymorphisms and enzyme activity in the western Indian population. Materials & methods: Angiographically proven coronary artery disease (CAD) formed the cases. PON1
Publikováno v:
Clinical Ethics. 13:189-193
Background Informed consent confers upon participants the right to decline or accept participation in a study in equal measure. Consent declines can be used as a potential metric to assess the adequacy of the informed consent process. Limited literat
Autor:
Nithya J Gogtay, Prasad S. Kulkarni, Peter S. Cheslock, Rajeev M. Dhere, Varsha Parulekar, B J Mahendra, D H Ashwath Narayana, B R Harish, William C. Blackwelder, Deborah C. Molrine, Renuka Munshi, Dipti Kumbhar, Sambhaji Shankar Pisal, Sunil Karande, Saket J. Thaker, Vikas D. Kshirsagar, Bhagwat Gunale, H S Ravish, Siddharth P Deshpande, Susan M. Moore
Publikováno v:
Clinical Infectious Diseases. 66:387-395
Background Lack of access to rabies immunoglobulin (RIG) contributes to high rabies mortality. A recombinant human monoclonal antibody (SII RMAb) was tested in a postexposure prophylaxis (PEP) regimen in comparison with a human RIG (HRIG)-containing
Autor:
Nithya J Gogtay, Urmila M Thatte, Shital R. Bendkhale, Prajakta Gandhe, Nitin B Mali, Charuta J. Godbole, Saket J. Thaker
Publikováno v:
Journal of Ayurveda and Integrative Medicine
Journal of Ayurveda and Integrative Medicine, Vol 8, Iss 1, Pp 37-41 (2017)
Journal of Ayurveda and Integrative Medicine, Vol 8, Iss 1, Pp 37-41 (2017)
Background Genetic polymorphisms in drug metabolizing enzymes (DMEs) impart distinct drug metabolizing capacity and a unique phenotype to an individual. Phenytoin has large inter-individual variability in metabolism due to polymorphisms in CYP2C9 and
Publikováno v:
The National medical journal of India. 31(2)
Background. The Consolidated Standards of Reporting Trials (CONSORT) statement has been developed to improve the quality of reporting of clinical trials. There is possibly suboptimal adherence to the CONSORT statement in published trials. We evaluate
Publikováno v:
The National medical journal of India. 30(5)
Background. The Central Standard Drugs Control Organization (CDSCO) issued an administrative order in November 201 3 mandating audiovisual (AV) recording of the informed consent process for all regulatory studies. At this point, a phase 2/3 trial ong
Publikováno v:
Clinical Epidemiology and Global Health. 3:52-57
Aim It is useful for a clinician to have a working knowledge of this science and hence this article reviews the essentials of pharmacoepidemiology for the practicing clinician. Methods This article is a compilation of information and examples from te