Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sakeenah L Hicks"'
Autor:
James R. Rose, Bagdeser Akdogan-Ozdilek, Andrew R. Rahmberg, Michael D. Powell, Sakeenah L. Hicks, Christopher D. Scharer, Jeremy M. Boss
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-19 (2023)
An integrated analysis uncovers transcriptional and epigenetic differences of human circulating memory T cell subsets and identifies unique transcription factor networks associated with memory subset differentiation.
Externí odkaz:
https://doaj.org/article/a067bd43035a480cbc06a1f70910044e
Autor:
Zhihong Zuo, Anna K. Kania, Dillon G. Patterson, Sakeenah L. Hicks, Jeffrey Maurer, Mansi Gupta, Jeremy M. Boss, Christopher D. Scharer
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e17527- (2023)
The transcription factor Interferon regulatory factor 8 (IRF8) is involved in maintaining B cell identity. However, how IRF8 regulates T cell independent B cell responses are not fully characterized. Here, an in vivo CRISPR/Cas9 system was optimized
Externí odkaz:
https://doaj.org/article/e2d535e0932a4c759017e58be7c52fae
Autor:
Christopher D. Scharer, Dillon G. Patterson, Tian Mi, Madeline J. Price, Sakeenah L. Hicks, Jeremy M. Boss
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The development of activated B cells into antibody-secreting cells (ASC) is a critical step for humoral immunity. Here the authors show, using adoptive transfers and single cell RNA sequencing, that commitment to ASC occurs soon following B cell acti
Externí odkaz:
https://doaj.org/article/279286b32b4a46bfa72d332ce28e2321
Autor:
Naohiko Ikegaki, Audrey E. Evans, Robert C. Seeger, Nai-Kong Cheung, Susan L. Cohn, Sakeenah L. Hicks, David Y. Kim, Bing Kung, Huaqing Zhao, Xao X. Tang
Supplementary Data from The MYCN Enigma: Significance of MYCN Expression in Neuroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652056c5b3922a554fe20fcf3394b41e
https://doi.org/10.1158/0008-5472.22366418.v1
https://doi.org/10.1158/0008-5472.22366418.v1
Autor:
Naohiko Ikegaki, Audrey E. Evans, Robert C. Seeger, Nai-Kong Cheung, Susan L. Cohn, Sakeenah L. Hicks, David Y. Kim, Bing Kung, Huaqing Zhao, Xao X. Tang
MYCN amplification strongly predicts adverse outcome of neuroblastoma. However, the significance of MYCN expression in the clinical and biological behavior of neuroblastoma has been unclear. To address this question, we first examined the expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbd8367ff3bc6103d8d2cb79ab1462f
https://doi.org/10.1158/0008-5472.c.6495131
https://doi.org/10.1158/0008-5472.c.6495131
Autor:
Anna K. Kania, Madeline J. Price, Lou-Ella George-Alexander, Dillon G. Patterson, Sakeenah L. Hicks, Christopher D. Scharer, Jeremy M. Boss
Publikováno v:
J Immunol
B cell differentiation is associated with substantial transcriptional, metabolic, and epigenetic remodeling, including redistribution of histone 3 lysine 27 trimethylation (H3K27me3), which is associated with a repressive chromatin state and gene sil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31bf75340854ccc07015a3a9e912776
https://pubmed.ncbi.nlm.nih.gov/35346967
https://pubmed.ncbi.nlm.nih.gov/35346967
Autor:
Chungwen Wei, Benjamin G. Barwick, Jeremy M. Boss, Christopher D. Scharer, Bridget E. Neary, Tsuneo Deguchi, Iñaki Sanz, Tian Mi, Arezou Khosroshahi, F. Eun-Hyung Lee, Scott A. Jenks, Dillon G. Patterson, Emily L. Blalock, Sakeenah L. Hicks, Kevin S. Cashman
Publikováno v:
Nature immunology
Systemic lupus erythematosus (SLE) is characterized by the expansion of extrafollicular pathogenic B cells derived from newly activated naive cells. Although these cells express distinct markers, their epigenetic architecture and how it contributes t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34abb8857af29ee011d71c48ba95799c
http://europepmc.org/articles/PMC6642679
http://europepmc.org/articles/PMC6642679
Autor:
Madeline J. Price, Christopher D. Scharer, Tian Mi, Jeremy M. Boss, Sakeenah L. Hicks, Dillon G. Patterson
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Upon stimulation, B cells assume heterogeneous cell fates, with only a fraction differentiating into antibody-secreting cells (ASC). Here we investigate B cell fate programming and heterogeneity during ASC differentiation using T cell-independent mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd0bf8e7311aa4aed3c3632c618f6827
http://europepmc.org/articles/PMC7417592
http://europepmc.org/articles/PMC7417592
Autor:
Rachelle L Stammen, Maria M Crane, Joyce Cohen, Jerrold S. Meyer, Kelly F Ethun, Rama Rao Amara, Sakeenah L. Hicks, Tracy L Meeker
Publikováno v:
Journal of the American Association for Laboratory Animal Science. 57:357-367
Because tetanus can cause significant morbidity and mortality in NHP, colonywide vaccination with tetanus toxoid is recommended for outdoor breeding colonies of rhesus macaques, with primary immunizations commonly given to infants at 6 mo of age foll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26103a53d737f985cf8d92f0c8aad834
https://doi.org/10.30802/aalas-jaalas-17-000102
https://doi.org/10.30802/aalas-jaalas-17-000102
Autor:
Smita S. Iyer, Steven E. Bosinger, Hadia M. Abdelaal, Daniel Rios, Sakeenah L. Hicks, Rafi Ahmed, Ifor R. Williams, Gregory K. Tharp, Geetha H. Mylvaganam, Maud Mavigner, Ann Chahroudi, Vijayakumar Velu, Rama Rao Amara, Pamela J. Skinner
Publikováno v:
Proceedings of the National Academy of Sciences. 114:1976-1981
A significant challenge to HIV eradication is the elimination of viral reservoirs in germinal center (GC) T follicular helper (Tfh) cells. However, GCs are considered to be immune privileged for antiviral CD8 T cells. Here, we show a population of si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49899f60159a758d8cda4610ed76d343
https://doi.org/10.1073/pnas.1621418114
https://doi.org/10.1073/pnas.1621418114