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Akademický článek

Discovery of SARS-CoV-2 papain-like protease (PL ^pro ) inhibitors with efficacy in a murine infection model.

Autor: Garnsey MR; Pfizer Global Research and Development, Cambridge, MA 02139, USA., Robinson MC; PostEra, 1 Broadway, 14th floor, Cambridge, MA 02142, USA., Nguyen LT; PostEra, 1 Broadway, 14th floor, Cambridge, MA 02142, USA., Cardin R; Pfizer Global Research and Development, Pearl River, NY 10965, USA., Tillotson J; Pfizer Global Research and Development, Cambridge, MA 02139, USA., Mashalidis E; Pfizer Global Research and Development, Groton, CT 06340, USA., Yu A; WuXi, WuXi AppTec (Shanghai) Co. Ltd. Shanghai 200131, China., Aschenbrenner L; Pfizer Global Research and Development, Groton, CT 06340, USA., Balesano A; Pfizer Global Research and Development, Groton, CT 06340, USA., Behzadi A; Pfizer Global Research and Development, Pearl River, NY 10965, USA., Boras B; Pfizer Global Research and Development, La Jolla, CA 92121, USA., Chang JS; Pfizer Global Research and Development, Groton, CT 06340, USA., Eng H; Pfizer Global Research and Development, Groton, CT 06340, USA., Ephron A; Pfizer Global Research and Development, Groton, CT 06340, USA., Foley T; Pfizer Global Research and Development, Groton, CT 06340, USA., Ford KK; Pfizer Global Research and Development, Groton, CT 06340, USA., Frick JM; PostEra, 1 Broadway, 14th floor, Cambridge, MA 02142, USA., Gibson S; Institute for Antiviral Research, Department of Animal, Dairy, and Veterinary Sciences,Utah State University, Logan, UT 84322, USA., Hao L; Pfizer Global Research and Development, Pearl River, NY 10965, USA., Hurst B; Institute for Antiviral Research, Department of Animal, Dairy, and Veterinary Sciences,Utah State University, Logan, UT 84322, USA., Kalgutkar AS; Pfizer Global Research and Development, Cambridge, MA 02139, USA., Korczynska M; Pfizer Global Research and Development, Cambridge, MA 02139, USA., Lengyel-Zhand Z; Pfizer Global Research and Development, Groton, CT 06340, USA., Gao L; WuXi, WuXi AppTec (Shanghai) Co. Ltd. Shanghai 200131, China., Meredith HR; Pfizer Global Research and Development, Cambridge, MA 02139, USA., Patel NC; Pfizer Global Research and Development, Cambridge, MA 02139, USA., Polivkova J; Pfizer Global Research and Development, Groton, CT 06340, USA., Rai D; Pfizer Global Research and Development, Groton, CT 06340, USA., Rose CR; Pfizer Global Research and Development, Groton, CT 06340, USA., Rothan H; Pfizer Global Research and Development, Pearl River, NY 10965, USA., Sakata SK; Pfizer Global Research and Development, La Jolla, CA 92121, USA., Vargo TR; PostEra, 1 Broadway, 14th floor, Cambridge, MA 02142, USA., Qi W; WuXi, WuXi AppTec (Shanghai) Co. Ltd. Shanghai 200131, China., Wu H; Pfizer Global Research and Development, Groton, CT 06340, USA., Liu Y; WuXi, WuXi AppTec (Shanghai) Co. Ltd. Shanghai 200131, China., Yurgelonis I; Pfizer Global Research and Development, Pearl River, NY 10965, USA., Zhang J; Pfizer Global Research and Development, Shanghai 201210, China., Zhu Y; Pfizer Global Research and Development, Pearl River, NY 10965, USA., Zhang L; Pfizer Global Research and Development, Cambridge, MA 02139, USA., Lee AA; PostEra, 1 Broadway, 14th floor, Cambridge, MA 02142, USA.

Publikováno v: Science advances [Sci Adv] 2024 Aug 30; Vol. 10 (35), pp. eado4288. Date of Electronic Publication: 2024 Aug 30.

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Akademický článek

Sandwich-like electrochemical aptasensing of heat shock protein 70 kDa (HSP70): Application in diagnosis/prognosis of coronavirus disease 2019 (COVID-19).

Autor: Negahdary M; Department of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, Av. Prof. Lineu Prestes, 748, 05508-000, São Paulo, Brazil. Electronic address: mnegahdary@iq.usp.br., Hirata MH; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of Sao Paulo, Av Prof Lineu Prestes 580, 05508-000, São Paulo, Brazil., Sakata SK; Nuclear and Energy Research Institute, National Commission of Nuclear Energy (IPEN/CNEN - SP), São Paulo, SP, 05508-000, Brazil., Ciconelli RM; Research and Education Division, Hospital A Beneficência Portuguesa de São Paulo, São Paulo, Brazil., Bastos GM; Research and Education Division, Hospital A Beneficência Portuguesa de São Paulo, São Paulo, Brazil., Borges JB; Research and Education Division, Hospital A Beneficência Portuguesa de São Paulo, São Paulo, Brazil., Thurow HS; Research and Education Division, Hospital A Beneficência Portuguesa de São Paulo, São Paulo, Brazil., Junior ATS; Department of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, Av. Prof. Lineu Prestes, 748, 05508-000, São Paulo, Brazil., Sampaio MF; Research and Education Division, Hospital A Beneficência Portuguesa de São Paulo, São Paulo, Brazil., Guimarães LB; Research and Education Division, Hospital A Beneficência Portuguesa de São Paulo, São Paulo, Brazil., Maeda BS; Research and Education Division, Hospital A Beneficência Portuguesa de São Paulo, São Paulo, Brazil., Angnes L; Department of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, Av. Prof. Lineu Prestes, 748, 05508-000, São Paulo, Brazil. Electronic address: luangnes@iq.usp.br.

Publikováno v: Analytica chimica acta [Anal Chim Acta] 2023 Feb 15; Vol. 1242, pp. 340716. Date of Electronic Publication: 2022 Dec 08.

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Akademický článek

Disposable electrochemical microfluidic device for ultrasensitive detection of egg allergen in wine samples.

Autor: Baldo TA; Departamento de Química, Universidade Federal de São Carlos, 13565-905, São Carlos, São Paulo, Brazil., Proença CDA; Departamento de Química, Universidade Federal de São Carlos, 13565-905, São Carlos, São Paulo, Brazil., Felix FDS; Departamento de Química, Universidade Federal de Lavras, CEP, 37200-900, Lavras, Minas Gerais, Brazil., Freitas TA; Departamento de Química, Universidade Federal de São Carlos, 13565-905, São Carlos, São Paulo, Brazil., Sakata SK; Centro de Tecnologia das Radiaçõs - Instituto de Pesquisa Energéticas e Nucleares (IPEN/CNEN-SP), CEP, 05508-000, São Paulo, São Paulo, Brazil., Angnes L; Instituto de Química, Universidade de São Paulo, CEP, 05508-000, São Paulo, São Paulo, Brazil., Faria RC; Departamento de Química, Universidade Federal de São Carlos, 13565-905, São Carlos, São Paulo, Brazil. Electronic address: rcfaria@ufscar.br.

Publikováno v: Talanta [Talanta] 2021 Sep 01; Vol. 232, pp. 122447. Date of Electronic Publication: 2021 May 01.

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Akademický článek

Employing Photocatalysis for the Design and Preparation of DNA-Encoded Libraries: A Case Study.

Autor: Kölmel DK; Worldwide Research and Development, Pfizer Inc, Eastern Point Road, Groton, CT 06340, United States., Zhu H; Worldwide Research and Development, Pfizer Inc, Eastern Point Road, Groton, CT 06340, United States., Flanagan ME; Worldwide Research and Development, Pfizer Inc, Eastern Point Road, Groton, CT 06340, United States., Sakata SK; Worldwide Research and Development, Pfizer Inc, 10770 Science Center Drive, San Diego, CA 92121, United States., Harris AR; Worldwide Research and Development, Pfizer Inc, Eastern Point Road, Groton, CT 06340, United States., Wan J; HitGen Inc Building 6, No. 8, Huigu first East Road, Tianfu International, Bio-Town, Shuangliu District, Chengdu City, Sichuan Province, P. R. China., Morgan BA; HitGen Inc Building 6, No. 8, Huigu first East Road, Tianfu International, Bio-Town, Shuangliu District, Chengdu City, Sichuan Province, P. R. China.; HitGen Pharmaceuticals Inc, PO Box 88240, Houston, TX 77288, United States.

Publikováno v: Chemical record (New York, N.Y.) [Chem Rec] 2021 Apr; Vol. 21 (4), pp. 616-630. Date of Electronic Publication: 2021 Feb 11.

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Akademický článek

Introduction of a Crystalline, Shelf-Stable Reagent for the Synthesis of Sulfur(VI) Fluorides.

Autor: Zhou H; BioDuro , No. 233 North FuTe Road, WaiGaoQiao Free Trade Zone, Shanghai 200131, P. R. China., Mukherjee P; Pfizer Worldwide Research and Development , Eastern Point Road, Groton, Connecticut 06340, United States., Liu R; BioDuro , No. 233 North FuTe Road, WaiGaoQiao Free Trade Zone, Shanghai 200131, P. R. China., Evrard E; Pfizer Worldwide Research and Development , 1 Portland Street, Cambridge, Massachusetts 02139, United States., Wang D; BioDuro , No. 233 North FuTe Road, WaiGaoQiao Free Trade Zone, Shanghai 200131, P. R. China., Humphrey JM; Pfizer Worldwide Research and Development , Eastern Point Road, Groton, Connecticut 06340, United States., Butler TW; Pfizer Worldwide Research and Development , Eastern Point Road, Groton, Connecticut 06340, United States., Hoth LR; Pfizer Worldwide Research and Development , Eastern Point Road, Groton, Connecticut 06340, United States., Sperry JB; Pfizer Worldwide Research and Development , Eastern Point Road, Groton, Connecticut 06340, United States., Sakata SK; Pfizer Worldwide Research and Development , 10770 Science Center Drive, San Diego, California 92121, United States., Helal CJ; Pfizer Worldwide Research and Development , Eastern Point Road, Groton, Connecticut 06340, United States., Am Ende CW; Pfizer Worldwide Research and Development , Eastern Point Road, Groton, Connecticut 06340, United States.

Publikováno v: Organic letters [Org Lett] 2018 Feb 02; Vol. 20 (3), pp. 812-815. Date of Electronic Publication: 2018 Jan 12.

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