Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Sakari Savolainen"'
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 102095- (2023)
Externí odkaz:
https://doaj.org/article/c108c5fe36f1446d906f7f68168cd4c4
Cerebrospinal fluid biomarker and brain biopsy findings in idiopathic normal pressure hydrocephalus.
Autor:
Okko T Pyykkö, Miikka Lumela, Jaana Rummukainen, Ossi Nerg, Toni T Seppälä, Sanna-Kaisa Herukka, Anne M Koivisto, Irina Alafuzoff, Lakshman Puli, Sakari Savolainen, Hilkka Soininen, Juha E Jääskeläinen, Mikko Hiltunen, Henrik Zetterberg, Ville Leinonen
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91974 (2014)
BackgroundThe significance of amyloid precursor protein (APP) and neuroinflammation in idiopathic normal pressure hydrocephalus (iNPH) and Alzheimer's disease (AD) is unknown.ObjectiveTo investigate the role of soluble APP (sAPP) and amyloid beta (A
Externí odkaz:
https://doaj.org/article/2474efa1786747989d060d4f63d44cbd
Preoperative MRI findings predict two-year postoperative clinical outcome in lumbar spinal stenosis.
Autor:
Pekka Kuittinen, Petri Sipola, Ville Leinonen, Tapani Saari, Sanna Sinikallio, Sakari Savolainen, Heikki Kröger, Veli Turunen, Olavi Airaksinen, Timo Aalto
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106404 (2014)
To study the predictive value of preoperative magnetic resonance imaging (MRI) findings for the two-year postoperative clinical outcome in lumbar spinal stenosis (LSS).84 patients (mean age 63±11 years, male 43%) with symptoms severe enough to indic
Externí odkaz:
https://doaj.org/article/2cdedc4c7afc4dfca3c4a66180043df5
Publikováno v:
Quality of Life Research. 27:3013-3020
Pain has a negative impact on life satisfaction (LS). Our primary aims were to compare LS in on-opioid and opioid-naive spine surgery patients and to evaluate whether surgery affects LS during the first 3 weeks after surgery. After informed consent 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12cc1f7b69cb4a74d2d62c6a2e80f8dc
https://doi.org/10.1007/s11136-018-1961-x
https://doi.org/10.1007/s11136-018-1961-x
Autor:
Sakari Savolainen, Timo Nyyssönen, Merja Kokki, Ira Pikkarainen, Hannu Kokki, Toivo Naaranlahti, Moona Kuronen
Publikováno v:
Advances in Therapy
Introduction Opioids are needed for postoperative pain in spine surgery patients, but opioid-induced constipation is a harmful adverse event. The aim of this clinical trial was to compare the use of a controlled-release oxycodone-naloxone combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e9dbb41dd6ba48977466e9d4078ab8
https://doi.org/10.1007/s12325-016-0456-9
https://doi.org/10.1007/s12325-016-0456-9
Autor:
Timo Nyyssönen, Kenneth M.C. Cheung, Juhani H Määttä, Juha Pesälä, Pirkka Mäkelä, Tatu Koskelainen, Eero Kyllönen, Jaro Karppinen, Ville Leinonen, Salme Järvenpää, Sakari Savolainen, Jaakko Niinimäki, Olavi Airaksinen, Hannu Kautiainen
Publikováno v:
Scandinavian Journal of Pain. 5:36-40
Background and purpose Modic changes (MC) are bone marrow and vertebral endplate lesions seen in magnetic resonance imaging (MRI) which have been found to be associated with low back pain (LBP), but the association between MC and health-related quali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a68cdc1941f1b01a4ba5158e0aa037f
https://doi.org/10.1016/j.sjpain.2013.08.003
https://doi.org/10.1016/j.sjpain.2013.08.003
Autor:
Ville Leinonen, Irina Alafuzoff, Jaana Rummukainen, Mitja I. Kurki, Anne M. Koivisto, Sakari Savolainen, Hilkka Soininen, Jaakko Rinne, Anna Sutela, Juha E. Jääskeläinen
Publikováno v:
Neurosurgery. 72:1-8
Idiopathic normal pressure hydrocephalus (iNPH) causes cognitive decline that can be alleviated by shunting, but long-term outcome studies are scarce.To elucidate the long-term cognitive condition of shunt-responsive iNPH patients.The follow-up data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9fafce63816c404fd4638ca8e30b73
https://doi.org/10.1227/neu.0b013e31827414b3
https://doi.org/10.1227/neu.0b013e31827414b3
Autor:
Irina Alafuzoff, Anne M. Koivisto, Jaana Rummukainen, Mitja I. Kurki, Ritva Vanninen, Sakari Savolainen, Ville Leinonen, Juha E. Jääskeläinen, Hilkka Soininen, Anna Sutela
Publikováno v:
Journal of Alzheimer's disease : JAD. 52(2)
Background Differential diagnosis of ventricular enlargement with normal pressure hydrocephalus (NPH) related symptoms is challenging. Patients with enlarged ventricles often manifest cognitive deterioration but their long-term outcome is not well kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cab2bc069afa1baa2c9674789f22f3f
https://pubmed.ncbi.nlm.nih.gov/27031474
https://pubmed.ncbi.nlm.nih.gov/27031474
Autor:
Tommi Kääriäinen, Sakari Savolainen, Ville Leinonen, Timo Aalto, Markku Kankaanpää, Arto Herno, Simo Taimela, Olavi Airaksinen, Veli Turunen, Heikki Kröger
Publikováno v:
European Spine Journal. 22:788-793
Impaired muscle function and lumbar proprioception have been observed in lumbar spinal stenosis (LSS) but those have not been studied in LSS patients with age-matched controls. We assessed lumbar movement perception and paraspinal and biceps brachii
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c55a06bb420c4cf947cfd75e01eade4
https://doi.org/10.1007/s00586-012-2563-x
https://doi.org/10.1007/s00586-012-2563-x
Autor:
Hilkka Soininen, Juhani A A Mölsä, Ville Leinonen, Juha E. Jääskeläinen, Anne M. Koivisto, Jaakko Rinne, Sakari Savolainen, Jaana Rummukainen, Irina Alafuzoff, Okko T. Pyykkö, Seppo Helisalmi, Ossi Nerg, Mikko Hiltunen
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 83:1119-1124
Objective To investigate the association of apolipoprotein E ( APOE ) genotype, especially the APOE4 allele, to (1) idiopathic normal pressure hydrocephalus (iNPH) and (2) amyloid-β (Aβ) plaques in cortical brain biopsies of presumed NPH patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11b215d5d3f00da8fc924136903a76d
https://doi.org/10.1136/jnnp-2011-303849
https://doi.org/10.1136/jnnp-2011-303849