Isolation, chemistry, and biology of pyrrolo[1,4]benzodiazepine natural products.

Autor: Sakaine G; Latvian Institute of Organic Synthesis, Riga, Latvia., Ture A; Latvian Institute of Organic Synthesis, Riga, Latvia., Pedroni J; Latvian Institute of Organic Synthesis, Riga, Latvia., Smits G; Latvian Institute of Organic Synthesis, Riga, Latvia.

Publikováno v: Medicinal research reviews [Med Res Rev] 2022 Jan; Vol. 42 (1), pp. 5-55. Date of Electronic Publication: 2021 Apr 13.

Lead Optimization of Phthalazinone Phosphodiesterase Inhibitors as Novel Antitrypanosomal Compounds.

Autor: Salado IG; Laboratory of Medicinal Chemistry, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium., Singh AK; School of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, United Kingdom., Moreno-Cinos C; Laboratory of Medicinal Chemistry, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium., Sakaine G; Laboratory of Medicinal Chemistry, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium., Siderius M; Medicinal Chemistry, Amsterdam Institute of Molecules, Medicines & Systems, Faculty of Science, Vrije Universiteit Amsterdam, 1081 Amsterdam, The Netherlands., Van der Veken P; Laboratory of Medicinal Chemistry, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium., Matheeussen A; Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium., van der Meer T; Medicinal Chemistry, Amsterdam Institute of Molecules, Medicines & Systems, Faculty of Science, Vrije Universiteit Amsterdam, 1081 Amsterdam, The Netherlands., Sadek P; Medicinal Chemistry, Amsterdam Institute of Molecules, Medicines & Systems, Faculty of Science, Vrije Universiteit Amsterdam, 1081 Amsterdam, The Netherlands., Gul S; Fraunhofer-IME SP, Schnackenburgallee 114, Hamburg 22525, Germany., Maes L; Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium., Sterk GJ; Medicinal Chemistry, Amsterdam Institute of Molecules, Medicines & Systems, Faculty of Science, Vrije Universiteit Amsterdam, 1081 Amsterdam, The Netherlands., Leurs R; Medicinal Chemistry, Amsterdam Institute of Molecules, Medicines & Systems, Faculty of Science, Vrije Universiteit Amsterdam, 1081 Amsterdam, The Netherlands., Brown D; School of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, United Kingdom., Augustyns K; Laboratory of Medicinal Chemistry, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2020 Apr 09; Vol. 63 (7), pp. 3485-3507. Date of Electronic Publication: 2020 Mar 26.

Modified Julia-Kocienski Reagents for a Stereoselective Introduction of Trisubstituted Double Bonds: A Formal Total Synthesis of Limazepine E and Barmumycin.

Autor: Sakaine G; Latvian Institute of Organic Synthesis , Aizkraukles 21 , Riga LV-1006 , Latvia., Smits G; Latvian Institute of Organic Synthesis , Aizkraukles 21 , Riga LV-1006 , Latvia.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2018 May 04; Vol. 83 (9), pp. 5323-5330. Date of Electronic Publication: 2018 Apr 18.

Julia‐Kocienski Olefination in the Synthesis of Trisubstituted Alkenes: Recent Progress.

Autor: Ouzounthanasis, Konstantinos A.¹ (AUTHOR), Rizos, Stergios R.² (AUTHOR), Koumbis, Alexandros E.¹ (AUTHOR) akoumbis@chem.auth.gr

Publikováno v: European Journal of Organic Chemistry. 9/21/2023, Vol. 26 Issue 36, p1-34. 34p.

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