Attenuation of the activated mammalian target of rapamycin pathway might be associated with renal function reserve by a low-protein diet in the rat remnant kidney model

Autor: Hiromichi Kumagai, Sakae Ohkawa, Tsuyoshi Uchikawa, Momoko Yanagida, Takuya Yoshida, Naoki Ikegaya

Publikováno v: Nutrition Research. 33:761-771

The mammalian target of rapamycin (mTOR), a regulator of cellular protein synthesis and cell growth, plays an important role in the progression of renal hypertrophy and renal dysfunction in experimental chronic kidney disease models. Because the mTOR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0556651b40c144ecca484c2e9208f3a
https://doi.org/10.1016/j.nutres.2013.06.003

Relaxin ameliorates salt-sensitive hypertension and renal fibrosis

Autor: Mari Odamaki, Takuya Yoshida, Natsuki Kobayashi, Hiromichi Kumagai, Tetsuya Kohsaka, Ayumi Suzuki, Naoki Ikegaya, Tatsuo Yamamoto, Sakae Ohkawa

Publikováno v: Nephrology Dialysis Transplantation. 27:2190-2197

Background Although relaxin (RLX) has potent vasodilatory and anti-fibrotic properties, there is no information on its effects on salt-sensitive hypertension. Methods We investigated the effects of short-term treatment with RLX on blood pressure (BP)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc8d0c582d9aa2d6734e5e7887c7232
https://doi.org/10.1093/ndt/gfr618

Annual Congress of the Chinese Blood Purification Center Administration Committee. March 20–23, 2008, Beijing

Autor: Roland M. Schmid, Hiromichi Kumagai, Kenji Arizono, Hiroyoshi Fukui, Polizo Kazila, Andreas Umgelter, Efi Yiannaki, Theodoros Eleftheriadis, Jia-qi Qian, Wieslawa Lysiak-Szydlowska, Mari Odamaki, Yoshiki Shiohira, Junichi Kadota, Bulent Altun, Jadranka Buturović-Ponikvar, Ester DeCostanzi, Jonas Axelsson, Ewa Aleksandrowicz, Tao Wang, Ryuichi Furuya, Vassilios Liakopoulos, Leszek Tylicki, Bolesław Rutkowski, Hui-Min Chen, Mustafa Arici, Bostjan Cebular, Takako Shimazu, Tomi Takamiya, Tomoko Sakata, Li-Juan Guo, Shigeki Toma, Ewa Król, Ai-wu Lin, Le-yi Gu, Bernhard Kreymann, Li-Jun Tang, Mehmet Bakkaloglu, Alper Kirkpantur, Barbaros Cil, Helga Frank, Saad Al Shohaib, Tuncay Aki, Dimitra Markala, Satonori Ueyama, Li-Tao Cheng, Jakob Gubensek, Enrico Sabbioni, Georgia Antoniadi, Kazuhiro Matsuyama, Wei Fang, Charalambos Kartsios, Qiang Yao, Abdelkarim Waness, Przemysław Rutkowski, Mahmut Ilker Yilmaz, Bengt Lindholm, Claudio Ronco, Nobuhiko Koga, Robert M. Kalicki, Marcin Renke, Dominik E. Uehlinger, Takeshi Nakata, Piero Stratta, Gerhard Lonnemann, Wolfgang Reindl, Makoto Matsuyama, Rafael Ponikvar, Caterina Canavese, Daniela Bergamo, Wolfgang Huber, Jens Lutz, Xiao-Yan Sun, Uwe Heemann, Yoshinao Uezu, Wojciech Larczyński, Yue Gu, Sakae Ohkawa, Akira Higa, Zhao-hui Ni, Zan-zhe Yu, Tadashi Tomo, Sami Bahlas, Cetin Turgan

Publikováno v: Blood Purification. 26:361-370

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac753879cb55e4108ebf05aa845b2d5e
https://doi.org/10.1159/000134287

Optimum dietary protein requirement in nondiabetic maintenance hemodialysis patients

Autor: Hiromichi Kumagai, Sakae Ohkawa, Yukiko Kaizu, Ikuo Hibi, Mari Odamaki, Naoki Ikegaya, Kunihiko Miyaji

Publikováno v: American Journal of Kidney Diseases. 43:454-463

Background: There is controversy about whether the dietary protein requirement of 1.2 g/kg/d for hemodialysis (HD) patients, in the nutritional guidelines recommended by the National Kidney Foundation-Kidney Disease Outcomes Quality Initiative (NKF-K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::307fe670d6ed5cbbec7235315ae8c333
https://doi.org/10.1053/j.ajkd.2003.10.042

Muscle mass index in haemodialysis patients: a comparison of indices obtained by routine clinical examinations

Autor: Yukiko Kaizu, Hiromichi Kumagai, Sakae Ohkawa

Publikováno v: Nephrology Dialysis Transplantation. 17:442-448

Background. Measurement of muscle mass is useful for evaluating protein nutritional status. Various methods for estimating muscle mass in haemodialysis patients have recently been developed. Methods. The validity of the estimate of creatinine product

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb54d235d1c95ef9ba94690456015b86
https://doi.org/10.1093/ndt/17.3.442