Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Saiyu Hang"'
Autor:
Audrey S Vanhove, Saiyu Hang, Vidhya Vijayakumar, Adam Cn Wong, John M Asara, Paula I Watnick
Publikováno v:
PLoS Pathogens, Vol 13, Iss 6, p e1006428 (2017)
Vibrio cholerae is a diarrheal pathogen that induces accumulation of lipid droplets in enterocytes, leading to lethal infection of the model host Drosophila melanogaster. Through untargeted lipidomics, we provide evidence that this process is the pro
Externí odkaz:
https://doaj.org/article/44bb72083947434aba1a99ae53ccc492
Publikováno v:
mBio, Vol 4, Iss 3 (2013)
ABSTRACT Vibrio cholerae is an estuarine bacterium and an intestinal pathogen of humans that causes severe epidemic diarrhea. In the absence of adequate mammalian models in which to study the interaction of V. cholerae with the host intestinal innate
Externí odkaz:
https://doaj.org/article/b8e4838e21f34963b52675c28363f6fd
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11498 (2010)
A hallmark of genes that are subject to developmental regulation of transcriptional elongation is association of the negative elongation factor NELF with the paused RNA polymerase complex. Here we use a combination of biochemical and genetic experime
Externí odkaz:
https://doaj.org/article/1c2cabc2fbe74e1cb61e25feb9566a81
Autor:
Lina Yao, Gabriel D. D’Agostino, Jinseok Park, Saiyu Hang, Arijit A. Adhikari, Yancong Zhang, Wei Li, Julian Avila-Pacheco, Sena Bae, Clary B. Clish, Eric A. Franzosa, Curtis Huttenhower, Jun R. Huh, A. Sloan Devlin
Publikováno v:
Nature Microbiology. 7:1404-1418
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd5b0768390a14cd19d037b3ed172615
https://doi.org/10.1038/s41564-022-01176-y
https://doi.org/10.1038/s41564-022-01176-y
Autor:
Meng Wu, Wen Zheng, Xinyang Song, Bin Bao, Yuanyou Wang, Deepshika Ramanan, Daping Yang, Rui Liu, John C. Macbeth, Elyza A. Do, Warrison A Andrade, Tiandi Yang, Hyoung-Soo Cho, Francesca S. Gazzaniga, Marit Ilves, Daniela Coronado, Charlotte Thompson, Saiyu Hang, Isaac M. Chiu, Jeffrey R. Moffitt, Ansel Hsiao, John J. Mekalanos, Christophe Benoist, Dennis L. Kasper
Publikováno v:
bioRxiv
Canonically, complement is a serum-based host defense system that protects against systemic microbial invasion. Little is known about the production and function of complement components on mucosal surfaces. Here we show gut complement component 3 (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e123493ed381fc22f2f57e2ae0c488
https://europepmc.org/articles/PMC9915568/
https://europepmc.org/articles/PMC9915568/
Autor:
Lina, Yao, Gabriel D, D'Agostino, Jinseok, Park, Saiyu, Hang, Arijit A, Adhikari, Yancong, Zhang, Wei, Li, Julian, Avila-Pacheco, Sena, Bae, Clary B, Clish, Eric A, Franzosa, Curtis, Huttenhower, Jun R, Huh, A Sloan, Devlin
Publikováno v:
Nature microbiology. 7(9)
Members of the human gut microbiome enzymatically process many bioactive molecules in the gastrointestinal tract. Most gut bacterial modifications characterized so far are hydrolytic or reductive in nature. Here we report that abundant human gut bact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::21ceb851381655c497dcd5544c1af305
https://pubmed.ncbi.nlm.nih.gov/35982309
https://pubmed.ncbi.nlm.nih.gov/35982309
Autor:
Yancong Zhang, Curtis Huttenhower, Megan D. McCurry, Gang Wang, Wei Li, Munhyung Bae, Yuan Fang, Sena Bae, A. Sloan Devlin, Eric A. Franzosa, Saiyu Hang, Jun R. Huh, Lina Yao
SUMMARYBile acids act as signaling molecules that regulate immune homeostasis, including the differentiation of CD4+T cells into distinct T cell subsets. The bile acid metabolite isoallolithocholic acid (isoalloLCA) enhances the differentiation of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::567c2c0acb2a265cea700bf987d32b5e
https://doi.org/10.1101/2021.01.08.425963
https://doi.org/10.1101/2021.01.08.425963
Autor:
Michael A. Fischbach, Ye Zheng, Lina Yao, Jun R. Huh, Fraydoon Rastinejad, A. Sloan Devlin, Samantha P. Kelly, Dan R. Littman, Jingping Lu, Randy S. Longman, Saiyu Hang, Eunha Kim, Soyoung Ha, Donggi Paik, Michael R. Krout, Brandon N. Nelson, Jamma Trinath, Lin Wu
Bile acids are abundant in the mammalian gut, where they undergo bacteria-mediated transformation to generate a large pool of bioactive molecules. Although bile acids are known to affect host metabolism, cancer progression and innate immunity, it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e6ca6e8892e89ae36b99e90f5f6de3
https://doi.org/10.1038/s41586-019-1785-z
https://doi.org/10.1038/s41586-019-1785-z
Autor:
Saiyu, Hang, Donggi, Paik, Lina, Yao, Eunha, Kim, Jamma, Trinath, Jingping, Lu, Soyoung, Ha, Brandon N, Nelson, Samantha P, Kelly, Lin, Wu, Ye, Zheng, Randy S, Longman, Fraydoon, Rastinejad, A Sloan, Devlin, Michael R, Krout, Michael A, Fischbach, Dan R, Littman, Jun R, Huh
Publikováno v:
Nature
Bile acids are abundant in the mammalian gut where they undergo bacteria-mediated transformation, generating a large pool of bioactive molecules. Although bile acids are known to affect host metabolism, cancer progression and innate immunity, it is u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dd0063fbf3004d30884f00cba3003eb3
https://pubmed.ncbi.nlm.nih.gov/31776512
https://pubmed.ncbi.nlm.nih.gov/31776512
Autor:
Saiyu Hang, Jun R. Huh
Publikováno v:
Cell. 179:803-805
How does stress promote anxiety? In this issue of Cell, Fan et al. report that immune cells have a direct role in this process. They show that chronic stress promotes mitochondrial fission in CD4+ T cells, causing increased synthesis of xanthine, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3de0c289182d83ae54d58304669a7253
https://doi.org/10.1016/j.cell.2019.10.012
https://doi.org/10.1016/j.cell.2019.10.012