Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Saira Hussain"'
Autor:
Amanda Hall, Helen Pryce, Rachel Shaw, Jonathan Banks, Georgina Burns-O'Connell, Rosemary Greenwood, Sian Noble, Rebecca Knibb, Jean Straus, Sian Karen Smith, Saira Hussain
Publikováno v:
BMJ Open, Vol 13, Iss 11 (2023)
Introduction Hearing loss is a common chronic health condition and adversely affects communication and social function resulting in loneliness, social isolation and depression. We know little about the patient experience of living with hearing loss a
Externí odkaz:
https://doaj.org/article/cb6c06bbccfa4cb0b52090c6318776d1
Publikováno v:
British Journal of Biomedical Science, Vol 80 (2023)
Modern and effective patient care requires specialist healthcare professionals working together. Interprofessional learning (IPL) seeks to provide opportunities for different healthcare disciplines to learn with, from and about each other. This study
Externí odkaz:
https://doaj.org/article/69c816adf81d4a018f654cc8cdf29718
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-6 (2022)
Electron cryotomography expands our knowledge of SARS-CoV-2 virus architecture and reveals a distinct and uniform morphology for which interactions between RNP subunits within the nucleocapsid and between the nucleocapsid and the membrane are likely
Externí odkaz:
https://doaj.org/article/73585c3234a44c0eaf62d5d0210df3e5
Autor:
Amanda Hall, Helen Pryce, Rachel Shaw, Jonathan Banks, Georgina Burns-O'Connell, Rosemary Greenwood, Rebecca Knibb, Jean Straus, Sian Karen Smith, Saira Hussain
Publikováno v:
BMJ Open, Vol 13, Iss 6 (2023)
Introduction Worldwide, hearing loss is a significant public health issue and one of the most common chronic health conditions experienced by older adults. Hearing loss is associated with communication difficulties, social withdrawal, isolation and l
Externí odkaz:
https://doaj.org/article/67f7509ae30e436f907c1da31b86f74f
Autor:
Antoni G. Wrobel, Donald J. Benton, Chloë Roustan, Annabel Borg, Saira Hussain, Stephen R. Martin, Peter B. Rosenthal, John J. Skehel, Steven J. Gamblin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-7 (2022)
The SARS-CoV-2 spike has been evolving in the human population. The variants of concern alpha and beta evolved to optimise spike openness and so ability to bind its receptor ACE2, the affinity towards the receptor, and stability upon receptor binding
Externí odkaz:
https://doaj.org/article/b4dd4e7327c04cb0a388bbe45794406e
Autor:
Tiong Kit Tan, Pramila Rijal, Rolle Rahikainen, Anthony H. Keeble, Lisa Schimanski, Saira Hussain, Ruth Harvey, Jack W. P. Hayes, Jane C. Edwards, Rebecca K. McLean, Veronica Martini, Miriam Pedrera, Nazia Thakur, Carina Conceicao, Isabelle Dietrich, Holly Shelton, Anna Ludi, Ginette Wilsden, Clare Browning, Adrian K. Zagrajek, Dagmara Bialy, Sushant Bhat, Phoebe Stevenson-Leggett, Philippa Hollinghurst, Matthew Tully, Katy Moffat, Chris Chiu, Ryan Waters, Ashley Gray, Mehreen Azhar, Valerie Mioulet, Joseph Newman, Amin S. Asfor, Alison Burman, Sylvia Crossley, John A. Hammond, Elma Tchilian, Bryan Charleston, Dalan Bailey, Tobias J. Tuthill, Simon P. Graham, Helen M. E. Duyvesteyn, Tomas Malinauskas, Jiandong Huo, Julia A. Tree, Karen R. Buttigieg, Raymond J. Owens, Miles W. Carroll, Rodney S. Daniels, John W. McCauley, David I. Stuart, Kuan-Ying A. Huang, Mark Howarth, Alain R. Townsend
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Vaccines for SARS-COV-2 are needed in the ongoing pandemic. Here the authors characterize a vaccine candidate that presents the receptor-binding domain (RBD) of SARS-CoV-2 spike protein on a synthetic VLP platform using SpyTag/SpyCatcher technology a
Externí odkaz:
https://doaj.org/article/6b95639b85804b348dfe9af334fe3bcf
Autor:
Antoni G. Wrobel, Donald J. Benton, Saira Hussain, Ruth Harvey, Stephen R. Martin, Chloë Roustan, Peter B. Rosenthal, John J. Skehel, Steven J. Gamblin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-5 (2020)
Here, the authors characterise the binding and neutralisation properties of CR3022, a neutralising Ab isolated from a convalescent SARS patient, against SARS-CoV-2 spike trimers and show using Cryo-EM the disruption of SARS-CoV-2 spike by CR3022 Fab.
Externí odkaz:
https://doaj.org/article/d4d4b2a7e1194f45b301bc4c82ffd83f
Autor:
Kuan-Ying A. Huang, Tiong Kit Tan, Ting-Hua Chen, Chung-Guei Huang, Ruth Harvey, Saira Hussain, Cheng-Pin Chen, Adam Harding, Javier Gilbert-Jaramillo, Xu Liu, Michael Knight, Lisa Schimanski, Shin-Ru Shih, Yi-Chun Lin, Chien-Yu Cheng, Shu-Hsing Cheng, Yhu-Chering Huang, Tzou-Yien Lin, Jia-Tsrong Jan, Che Ma, William James, Rodney S. Daniels, John W. McCauley, Pramila Rijal, Alain R. Townsend
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12 (2021)
Externí odkaz:
https://doaj.org/article/07994aa424a748049a6a28635621c19d
Autor:
Nikhil Faulkner, Kevin W Ng, Mary Y Wu, Ruth Harvey, Marios Margaritis, Stavroula Paraskevopoulou, Catherine Houlihan, Saira Hussain, Maria Greco, William Bolland, Scott Warchal, Judith Heaney, Hannah Rickman, Moria Spyer, Daniel Frampton, Matthew Byott, Tulio de Oliveira, Alex Sigal, Svend Kjaer, Charles Swanton, Sonia Gandhi, Rupert Beale, Steve J Gamblin, John W McCauley, Rodney Stuart Daniels, Michael Howell, David Bauer, Eleni Nastouli, George Kassiotis
Publikováno v:
eLife, Vol 10 (2021)
Background: The degree of heterotypic immunity induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains is a major determinant of the spread of emerging variants and the success of vaccination campaigns, but remains incompletel
Externí odkaz:
https://doaj.org/article/53554e64b4f947678adda363fb937cb8
Autor:
Kuan-Ying A Huang, Tiong Kit Tan, Ting-Hua Chen, Chung-Guei Huang, Ruth Harvey, Saira Hussain, Cheng-Pin Chen, Adam Harding, Javier Gilbert-Jaramillo, Xu Liu, Michael Knight, Lisa Schimanski, Shin-Ru Shih, Yi-Chun Lin, Chien-Yu Cheng, Shu-Hsing Cheng, Yhu-Chering Huang, Tzou-Yien Lin, Jia-Tsrong Jan, Che Ma, William James, Rodney S Daniels, John W McCauley, Pramila Rijal, Alain R Townsend
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009352 (2021)
Serological and plasmablast responses and plasmablast-derived IgG monoclonal antibodies (MAbs) have been analysed in three COVID-19 patients with different clinical severities. Potent humoral responses were detected within 3 weeks of onset of illness
Externí odkaz:
https://doaj.org/article/7e9ce5b081804c2fbe263952aa0c1f4f