Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Saiphone Webb"'
Autor:
Lyndah Chow, Valerie Johnson, Dan Regan, William Wheat, Saiphone Webb, Peter Koch, Steven Dow
Publikováno v:
Stem Cell Research, Vol 25, Iss C, Pp 221-232 (2017)
Mesenchymal stem cells (MSCs) exhibit broad immune modulatory activity in vivo and can suppress T cell proliferation and dendritic cell activation in vitro. Currently, most MSC for clinical usage are derived from younger donors, due to ease of procur
Externí odkaz:
https://doaj.org/article/a2f87df7b2e240cea2958eaa5269780f
Autor:
Maddison N. Salois, Jessica A. Gugger, Saiphone Webb, Christina E. Sheldon, Shirley P. Parraga, G. Michael Lewitt, Dorothy K. Grange, Peter J. Koch, Maranke I. Koster
Publikováno v:
bioRxiv
The goal of this study was to investigate the molecular mechanisms responsible for the formation of skin erosions in patients affected by Ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (AEC). This ectodermal dysplasia is caused by mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc838e53f3faa03317137359ff5924a0
https://europepmc.org/articles/PMC10187256/
https://europepmc.org/articles/PMC10187256/
Publikováno v:
Current Protocols. 2
Investigating basic biological mechanisms underlying human diseases relies on the availability of sufficient quantities of patient cells. As most primary somatic cells have a limited lifespan, obtaining sufficient material for biological studies has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d1054506d844cc06793407fd1c16d5
https://doi.org/10.1002/cpz1.408
https://doi.org/10.1002/cpz1.408
Autor:
G. Scott Worthen, Benjamin T. Suratt, Gordon Keller, Saiphone Webb, Scott K. Young, Gary L. Johnson, Jonathan G. Lieber
Publikováno v:
Blood. 103:852-859
An embryonic stem (ES) cell/OP9 coculture system for the effective production of functional neutrophils is described. A 3-step differentiation strategy was developed that uses liquid culture, enabling reliable and abundant production of neutrophils a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0cd7caedba6772987562f636ca620b2
https://doi.org/10.1182/blood-2003-04-1030
https://doi.org/10.1182/blood-2003-04-1030
Autor:
Tamotsu Ishizuka, Gary L. Johnson, Spencer B. Gibson, Sue Sather, Gordon Keller, David M. Russell, Weiyong Sun, Kosuke Chayama, Philip J. Papst, Saiphone Webb, Toshiaki Yujiri, Timothy P. Garrington, Erwin W. Gelfand
Publikováno v:
The EMBO Journal. 19:5387-5395
Ligation of the high-affinity IgE receptor (FcepsilonRI) or of c-Kit stimulates cytokine production in mast cells. We show that MEK kinase 2 (MEKK2), a MAPK kinase kinase (MAP3K) that regulates the JNK and ERK5 pathways, is required for cytokine prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b69f620f12cc44c6026b8c5ac13ebd
https://doi.org/10.1093/emboj/19.20.5387
https://doi.org/10.1093/emboj/19.20.5387
Autor:
Dazhi Cen, Saiphone Webb, Lesley J. Murray, Robert S. Negrin, Janet Condino, Benjamin P. Chen, Anne Galy
Publikováno v:
Blood. 84:104-110
The present study compared the T-cell progenitor content of CD34+ lineage (Lin)- cells isolated from normal adult bone marrow (ABM) and mobilized peripheral blood (MPB). Both cell populations were found to differentiate into T cells when injected int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9045f0ec0f5b4a36c3b61eda85cd2b8c
https://doi.org/10.1182/blood.v84.1.104.104
https://doi.org/10.1182/blood.v84.1.104.104
Publikováno v:
Methods in molecular medicine. 63
Under appropriate culture conditions, ES cells will spontaneously differentiate and generate colonies known as embryoid bodies (EBs) that contain precursors of multiple lineages, including those of the hematopoietic system (1-7). Previous studies hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7095d14768352135b200528c4fc90d73
https://pubmed.ncbi.nlm.nih.gov/21437810
https://pubmed.ncbi.nlm.nih.gov/21437810
Autor:
Timothy P. Garrington, Razvan Lapadat, Weiyong Sun, Katherine E. Lobel-Rice, Kamala Kesavan, Gary L. Johnson, Saiphone Webb
Publikováno v:
Journal of cellular physiology. 199(1)
Mitogen-activated protein kinases (MAPKs) are regulated by MAPK kinases (MKKs), which are in turn regulated by MKK kinases (MKKKs). While a single MKKK can regulate several different MAPK family members, and several MKKKs can often activate the same
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2f83dd2188b9986f1644f5b465daa6
https://pubmed.ncbi.nlm.nih.gov/14978743
https://pubmed.ncbi.nlm.nih.gov/14978743
Autor:
Anthony Joetham, Gary L. Johnson, Erwin W. Gelfand, Weiyong Sun, Ruihua Fan, Timothy P. Garrington, Xudong Wei, Saiphone Webb, Joseph J. Lucas, Guiming Li, Joanne Hahn, Azzeddine Dakhama
Publikováno v:
European journal of immunology. 33(10)
Mitogen-activated protein kinase (MAPK) cascades play essential roles in the transduction of extracellular signals to cytoplasmic and nuclear effectors. The MAPK kinase kinase MEKK2 is essential for activation of c-Jun N-terminal kinase (JNK) and ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a2b9a2eb508e47ebc133c490adf607
https://pubmed.ncbi.nlm.nih.gov/14515274
https://pubmed.ncbi.nlm.nih.gov/14515274
Autor:
Soula Ganiatsas, Timothy P. Garrington, Philip J. Papst, Tamotsu Ishizuka, Gary L. Johnson, Kosuke Chayama, Saiphone Webb, Erwin W. Gelfand, Joanne C. Pratt, Leonard I. Zon, Weiyong Sun
Cross-linking of the high-affinity IgE receptor (FcepsilonRI) on mast cells with IgE and multivalent antigen triggers mitogen-activated protein (MAP) kinase activation and cytokine gene expression. We report here that MAP kinase kinase 4 (MKK4) gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::debe2f61be3667e139812f52c792e21c
https://europepmc.org/articles/PMC31880/
https://europepmc.org/articles/PMC31880/