Zobrazeno 1 - 10
of 722
pro vyhledávání: '"Saintigny, P."'
Autor:
François Virard, Stéphane Giraud, Mélanie Bonnet, Léa Magadoux, Laetitia Martin, Thuy Ha Pham, Najwa Skafi, Sophie Deneuve, Rita Frem, Bruno O. Villoutreix, Nawal Hajj Sleiman, Jonathan Reboulet, Samir Merabet, Vincent Chaptal, Cédric Chaveroux, Nader Hussein, Nicolas Aznar, Tanguy Fenouil, Isabelle Treilleux, Pierre Saintigny, Stéphane Ansieau, Serge Manié, Serge Lebecque, Toufic Renno, Isabelle Coste
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The quest for targeted therapies is critical in the battle against cancer. The RAS/MAP kinase pathway is frequently implicated in neoplasia, with ERK playing a crucial role as the most distal kinase in the RAS signaling cascade. Our previous
Externí odkaz:
https://doaj.org/article/5f91f695de8442caa6ead3b1243c6294
Autor:
Armelle Dufresne, Valéry Attignon, Anthony Ferrari, Laurie Tonon, Sandrine Boyault, Séverine Tabone‐Eglinger, Philippe Cassier, Olivier Trédan, Nadège Corradini, Armelle Vinceneux, Aurélie Swalduz, Alain Viari, Sylvie Chabaud, David Pérol, Jean Yves Blay, Pierre Saintigny
Publikováno v:
Cancer Medicine, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Introduction The objective was to determine the added value of comprehensive molecular profile by whole‐exome and RNA sequencing (WES/RNA‐Seq) in advanced and refractory cancer patients who had no molecular‐based treatment recommendati
Externí odkaz:
https://doaj.org/article/9b729f0973334b92809d58a905b67735
Autor:
Anda Huna, Jean-Michel Flaman, Catalina Lodillinsky, Kexin Zhu, Gabriela Makulyte, Victoria Pakulska, Yohann Coute, Clémence Ruisseaux, Pierre Saintigny, Hector Hernandez-Vargas, Pierre-Antoine Defossez, Mathieu Boissan, Nadine Martin, David Bernard
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-16 (2023)
Abstract Background TGFβ induces several cell phenotypes including senescence, a stable cell cycle arrest accompanied by a secretory program, and epithelial-mesenchymal transition (EMT) in normal epithelial cells. During carcinogenesis cells lose th
Externí odkaz:
https://doaj.org/article/366dc4f5a8974d69aeb31558a29f5fe0
Autor:
Juliette Dessemon, Olivia Perol, Cécile Chauvel, Hugo Noelle, Thomas Coudon, Lény Grassot, Nicolas Foray, Elodie Belladame, Jérôme Fayette, Françoise Fournie, Aurélie Swalduz, Eve-Marie Neidhart, Pierre Saintigny, Mayeul Tabutin, Maxime Boussageon, Frédéric Gomez, Virginie Avrillon, Maurice Perol, Barbara Charbotel, Béatrice Fervers
Publikováno v:
Frontiers in Public Health, Vol 11 (2024)
IntroductionResidential exposure is estimated to be responsible for nearly 10% of lung cancers in 2015 in France, making it the second leading cause, after tobacco. The Auvergne-Rhône-Alpes region, in the southwest of France, is particularly affecte
Externí odkaz:
https://doaj.org/article/59eed2ed0592472bacd7aa9539ba0b7b
Autor:
Juliette Mainguené, Sophie Vacher, Maud Kamal, Abderaouf Hamza, Julien Masliah‐Planchon, Sylvain Baulande, Sabrina Ibadioune, Edith Borcoman, Wulfran Cacheux, Valentin Calugaru, Laura Courtois, Carole Crozes, Marc Deloger, Elodie Girard, Jean‐Pierre Delord, Antoine Dubray‐Vautrin, Linda Larbi Chérif, Celia Dupain, Emmanuelle Jeannot, Jerzy Klijanienko, Sonia Lameiras, Charlotte Lecerf, Anouchka Modesto, Alain Nicolas, Roman Rouzier, Esma Saada‐Bouzid, Pierre Saintigny, Anne Sudaka, Nicolas Servant, Christophe Le Tourneau, Ivan Bièche
Publikováno v:
Molecular Oncology, Vol 16, Iss 16, Pp 3001-3016 (2022)
A prevalence of around 26% of human papillomavirus (HPV) in head and neck squamous cell carcinoma (HNSCC) has been previously reported. HPV induced oncogenesis mainly involving E6 and E7 viral oncoproteins. In some cases, HPV viral DNA has been detec
Externí odkaz:
https://doaj.org/article/d06dd36b1af84cd3acb67648ff2cbc2c
Autor:
Benjamin Solomon, Ana Callejo, Jair Bar, Guy Berchem, Lyudmila Bazhenova, Pierre Saintigny, Fanny Wunder, Jacques Raynaud, Nicolas Girard, J. Jack Lee, Raed Sulaiman, Bruce Prouse, Catherine Bresson, Hila Ventura, Shai Magidi, Eitan Rubin, Brandon Young, Amir Onn, Brian Leyland‐Jones, Richard L. Schilsky, Vladimir Lazar, Enriqueta Felip, Razelle Kurzrock
Publikováno v:
Cancer Medicine, Vol 11, Iss 14, Pp 2790-2800 (2022)
Abstract Background The Worldwide Innovative Network (WIN) Consortium has developed the Simplified Interventional Mapping System (SIMS) to better define the cancer molecular milieu based on genomics/transcriptomics from tumor and analogous normal tis
Externí odkaz:
https://doaj.org/article/9a1795592c8e42cab3df58cfe6f8ac80
Akademický článek
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Akademický článek
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Autor:
Amine Bouhamama, Benjamin Leporq, Khuram Faraz, Jean-Philippe Foy, Maxime Boussageon, Maurice Pérol, Sandra Ortiz-Cuaran, François Ghiringhelli, Pierre Saintigny, Olivier Beuf, Frank Pilleul
Publikováno v:
Frontiers in Radiology, Vol 3 (2023)
IntroductionIn this study, we aim to build radiomics and multiomics models based on transcriptomics and radiomics to predict the response from patients treated with the PD-L1 inhibitor.Materials and methodsOne hundred and ninety-five patients treated
Externí odkaz:
https://doaj.org/article/d51f1dbd8d0c49318bdb70da0d9c489c
Autor:
Tan Mai Nguyen, Chloé Bertolus, Paul Giraud, Anita Burgun, Pierre Saintigny, Jean-Emmanuel Bibault, Jean-Philippe Foy
Publikováno v:
Cancers, Vol 15, Iss 22, p 5369 (2023)
Background: We recently developed a gene-expression-based HOT score to identify the hot/cold phenotype of head and neck squamous cell carcinomas (HNSCCs), which is associated with the response to immunotherapy. Our goal was to determine whether radio
Externí odkaz:
https://doaj.org/article/0e121870c5b94d55bac79ef6cddcb9a9