Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sain Shushanov"'
Autor:
Sain Shushanov, Teresa L. Wood, Lauren Rota, Derek LeRoith, Marcus E Shin, Lidia Albanito, Emily J. Gallagher, Corey Goyeneche, Deborah A Lazzarino
Publikováno v:
Cancer Research. 74:5668-5679
Triple-negative breast cancer (TNBC) is an aggressive disease subtype that, unlike other subtypes, lacks an effective targeted therapy. Inhibitors of the insulin-like growth factor receptor (IGF1R) have been considered for use in treating TNBC. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4688e5eba5c020f1e74f4ef63cb1d8a
https://doi.org/10.1158/0008-5472.can-14-0970
https://doi.org/10.1158/0008-5472.can-14-0970
Publikováno v:
Endocrinology. 152:3233-3245
The IGFs and the IGF type 1 receptor (IGF-1R) are essential mediators of normal mammary gland development in mice. IGF-I and the IGF-1R have demonstrated functions in formation and proliferation of terminal end buds and in ductal outgrowth and branch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c305f92210d28b608929ad41fd0cd7e
https://doi.org/10.1210/en.2010-1296
https://doi.org/10.1210/en.2010-1296
Publikováno v:
Blood. 128:5144-5144
Multidrug resistance (MDR) is the biological phenomenon, significantly reduces the survival of patients with multiple myeloma (MM) to the conventional chemotherapy. Overexpression of MDR gene (MDR1, MRP1, LRP, BCRP) by plasma cells may be clinically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd49d7441bbd4610d8c211351870963b
https://doi.org/10.1182/blood.v128.22.5144.5144
https://doi.org/10.1182/blood.v128.22.5144.5144
Autor:
Kathryn F. LaNoue, Mark Kester, Sumathi Shanmugam, Paul F. Gomez, Thomas W. Gardner, Patrick G. Quinn, Sain Shushanov, Steve F. Abcouwer, Alistair J. Barber
Publikováno v:
Investigative ophthalmologyvisual science. 49(12)
Purpose Interleukin-(IL)1beta expression is increased in the retina during a variety of diseases involving the death of retinal neurons and contributes to neurodegenerative processes through an unknown mechanism. This study was conducted to examine t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf6a3ae047daad343b628411b1643f8
https://pubmed.ncbi.nlm.nih.gov/19037001
https://pubmed.ncbi.nlm.nih.gov/19037001
Autor:
Alla Stavrovskaya, Tamara Tchipysheva, Jocelyne Jacquemier, Sain Shushanov, Lotta Jussila, José Adélaïde, Aïda Karamysheva, Daniel Birnbaum, Maria Bronstein
Publikováno v:
International journal of cancer. 86(1)
In vertebrates, vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are major determinants of angiogenesis. In adults, the interaction between VEGFc and VEGFR3 (previously FLT4) is more specifically involved in the biology of lym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e57cee8a5cd94ac3a9a5de73d3adff
https://pubmed.ncbi.nlm.nih.gov/10728593
https://pubmed.ncbi.nlm.nih.gov/10728593